| Cluster | HMM | Locus | Description | COG | Pfam | Smart | Swiss-Prot |
|---|
| 2320 |
|
| putative toxin subunit|Rhs family protein [Cell envelope biogenesis, outer membrane]; COG3209|Dual specificity phosphatase, catalytic domain. Ser/Thr and Tyr protein phosphatases. The enzyme's tertiary fold is highly similar to that of tyrosine-specific phosphatases, except for a 'recognition' region; pfam00782|hypothetical protein; PRK12361 | COG3209(22) | PF00782(5), PF03497(6) | | |
| 2360 |
|
| putative non-ribosomal peptide synthase|Beta-ketoacyl synthase, N-terminal domain. The structure of beta-ketoacyl synthase is similar to that of the thiolase family (Pfam::PF00108) and also chalcone synthase; pfam00109|polyketide synthases (PKSs) polymerize simple fatty acids into a large variety of different products, called polyketides, by successive decarboxylating Claisen condensations; cd00833|Polyketide synthase modules and related proteins [Secondary metabolites biosynthesis, transport, and catabolism]; COG3321|AMP-binding enzyme; pfam00501|D-alanine--D-alanyl carrier protein ligase; PRK04813 | COG3321(3)|COG1020(3), COG3433(9)|COG1020(9), COG1022(2)|COG1020(2), COG1020(9) | PF00668(5)|PF08415(5)|PF00501(5)|PF08242(5)|PF00550(5)|PF00975(5), PF00109(3)|PF00550(3)|PF00668(3)|PF08415(3)|PF00501(3), PF00668(4)|PF08415(4)|PF00501(4)|PF00550(4), PF00668(1)|PF08415(1)|PF00501(1)|PF08242(1), PF00550(2)|PF00109(2)|PF00668(2)|PF08415(2)|PF00501(2), PF00668(8)|PF08415(8)|PF00501(8)|PF08242(8)|PF00550(8) | | |
| 2401 |
|
| putative hemolysin activator HlyB|Hemolysin activation/secretion protein [Intracellular trafficking and secretion]; COG2831|POTRA domain, ShlB-type. The POTRA domain (for polypeptide-transport-associated domain) is found towards the N-terminus of ShlB family proteins (pfam03865). ShlB is important in the secretion and activation of the haemolysin ShlA; pfam08479|Haemolysin secretion/activation protein ShlB/FhaC/HecB. This family represents a group of sequences that are related to ShlB from Serratia marcescens; pfam03865 | COG2831(24) | PF08479(24)|PF03865(24) | | |
| 2686 |
|
| putative membrane proteins|Peptidase family M23. Members of this family are zinc metallopeptidases with a range of specificities. The peptidase family M23 is included in this family, these are Gly-Gly endopeptidases. Peptidase family M23 are also endopeptidases; pfam01551|related to metalloendopeptidases | COG3179(12) | PF01551(17) | | |
| 2865 |
|
| putative exported protein|Pertactin-like passenger domains (virulence factors), C-terminal, subgroup 2, of autotransporter proteins of the type V secretion system of Gram-negative bacteria; cd01344|Autotransporter beta-domain. Secretion of protein products occurs by a number of different pathways in bacteria. One of these pathways known as the type V pathway was first described for the IgA1 protease; pfam03797|highly similar to Yersinia pestis CO92 YPO0309 and Yersinia pestis KIM y0567. Contains Autotransporter beta-domain (Interpro|IPR005546). Contains Outer membrane autotransporter barrel (Interpro|IPR006315) | | PF03797(19) | | |
| 2996 |
|
| putative integrase protein|Integrase core domain. Integrase mediates integration of a DNA copy of the viral genome into the host chromosome. Integrase is composed of three domains. The amino-terminal domain is a zinc binding domain pfam02022; pfam00665 | COG2801(5) | PF00665(23) | | |
| 3287 |
|
| putative inner membrane ABC-transporter (YbtP)|ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; COG1132|ABC transporter transmembrane region. This family represents a unit of six transmembrane helices. Many members of the ABC transporter family (pfam00005) have two such regions; pfam00664|MsbA is an essential ABC transporter, closely related to eukaryotic MDR proteins; cd03251|The catalytic domains of Rad50 are similar to the ATP-binding cassette of ABC transporters, but are not associated with membrane-spanning domains; cd03240 | COG1132(15) | PF00664(15) | | |
| 3293 |
|
| Putative exported protein|Similar to Yersinia pestis putative exported protein ypo2884 SWALL:Q8ZCT1 (EMBL:AJ414154) (806 aa) fasta scores: E(): 5.6e-49, 38.06 38d in 444 aa | COG1247(1) | PF09101(6), PF00583(7) | SM00247(8) | |
| 3355 |
|
| putative flagellin|Flagellin and related hook-associated proteins [Cell motility and secretion]; COG1344|Bacterial flagellin N-terminus. Flagellins polymerise to form bacterial flagella. This family includes flagellins and hook associated protein 3; pfam00669 | COG1344(9) | PF00669(9) | | |
| 3372 |
|
| hypothetical protein|Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; cd00093 | | | | |
| 3374 |
|
| probable hemagglutinin-related protein|haemagglutination activity domain. This domain is suggested to be a carbohydrate- dependent haemagglutination activity site. It is found in a range of haemagglutinins and haemolysins; pfam05860 | COG3210(12) | PF05860(15) | | |
| 3438 |
|
| probable amidase|Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases [Translation, ribosomal structure and biogenesis]; COG0154|amidase; PRK06170 | COG0154(9) | | | |
| 3443 |
|
| exopolygalacturonate lyase|Periplasmic pectate lyase. This family consists of several Enterobacterial periplasmic pectate lyase proteins (EC:4.2.2.2); pfam06917 | | PF06917(14) | | P11278(1) |
| 3454 |
|
| putative transporter, permease protein|Binding-protein-dependent transport system inner membrane component. The alignments cover the most conserved region of the proteins, which is thought to be located in a cytoplasmic loop between two transmembrane domains. The members of this family have...; cl00427 | | | | |
| 3489 |
|
| putative cation transport protein|Cation transporter/ATPase, N-terminus. Members of this families are involved in Na+/K+, H+/K+, Ca++ and Mg++ transport; pfam00690|E1-E2 ATPase; pfam00122|haloacid dehalogenase-like hydrolase. This family are structurally different from the alpha/ beta hydrolase family (pfam00561). This family includes L-2-haloacid dehalogenase, epoxide hydrolases and phosphatases; pfam00702 | COG0474(9) | PF00690(7)|PF00122(7)|PF00702(7)|PF08282(7)|PF00689(7), PF00690(2)|PF00122(2)|PF00702(2)|PF00689(2) | | |
| 3517 |
|
| PapA|Fimbrial protein; cl01416 | | PF00419(1) | | |
| 3573 |
|
| hypothetical TonB dependent receptor|Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; COG1629|TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; cd01347 | COG1629(11) | | | |
| 3585 |
|
| hypothetical protein|HNH endonuclease; pfam01844|highly similar to Yersinia pestis CO92 YPO0639 and Yersinia pestis KIM y3543. Contains HNH endonuclease (Interpro|IPR002711, (GO:0004519)) | | PF01844(9) | | |
| 3589 |
|
| putative transposase-related protein|Transposase. Transposase proteins are necessary for efficient DNA transposition. This family consists of various E. coli insertion elements and other bacterial transposases some of which are members of the IS3 family; pfam01527 | | PF01527(7) | | |
| 3606 |
|
| putative ABC transporter transporter, ATP-binding protein|The ABC transporter subfamily specific for the transport of dipeptides, oligopeptides (OppD), and nickel (NikDE). The NikABCDE system of E; cd03257|The pleiotropic drug resistance (PDR) family of ATP-binding cassette (ABC) transporters. PDR is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes; cd03233 | COG1124(8) | | | |
| 3607 |
|
| putative ABC transporter ATP-binding protein|ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; COG1124|The ABC transporter subfamily specific for the transport of dipeptides, oligopeptides (OppD), and nickel (NikDE). The NikABCDE system of E; cd03257 | COG1124(11) | | | |
| 3656 |
|
| hypothetical protein,,,, | | | | |
| 3659 |
|
| Putative oligogalacturonide transporter|Na+/melibiose symporter and related transporters [Carbohydrate transport and metabolism]; COG2211|Residues 16 to 496 of 504 are 56.93 pct identical to residues 13 to 495 of 508 from GenPept.129 : >emb|CAC44457.1| (AJ305143) oligogalacturonide transporter [Pectobacterium chrysanthemi] | COG2211(10) | | | |
| 3668 |
|
| putative exported protein|highly similar to Yersinia pestis CO92 YPO0901 and Yersinia pestis KIM y3286. | | | | |
| 3731 |
|
| sugar ABC transporter, permease protein|Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components [Carbohydrate transport and metabolism]; COG1172|identified by match to protein family HMM PF02653 | COG1172(12) | PF02653(1) | | |
| 3732 |
|
| sugar ABC transporter, permease protein|Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components [Carbohydrate transport and metabolism]; COG1172|identified by match to protein family HMM PF02653 | COG1172(12) | PF02653(1) | | |
| 3733 |
|
| sugar ABC transporter, periplasmic sugar-binding protein|ABC-type xylose transport system, periplasmic component [Carbohydrate transport and metabolism]; COG4213 | COG4213(5), COG1879(4)|COG4213(4), COG4213(3)|COG1879(3) | | | |
| 3749 |
|
| putative sugar phosphate isomerases/epimerases|Sugar phosphate isomerases/epimerases [Carbohydrate transport and metabolism]; COG1082|AP endonuclease family 2; These endonucleases play a role in DNA repair; cd00019 | COG1082(9) | PF01261(8) | | |
| 3762 |
|
| putative hemolysin|haemagglutination activity domain. This domain is suggested to be a carbohydrate- dependent haemagglutination activity site. It is found in a range of haemagglutinins and haemolysins; pfam05860 | COG3210(5) | PF05860(12) | | |
| 3772 |
|
| putative endolysin | | | | |
| 3844 |
|
| putative aldehyde dehydrogenase|1-pyrroline-5-carboxylate dehydrogenase; PRK03137|Aldehyde dehydrogenase family. This family of dehydrogenases act on aldehyde substrates. Members use NADP as a cofactor. The family includes the following members: The prototypical members are the aldehyde dehydrogenases EC:1.2.1.3; pfam00171 | COG1012(1) | PF00171(7) | | |
| 3847 |
|
| Putative glucosidase|Glycosyl hydrolases family 31. Glycosyl hydrolases are key enzymes of carbohydrate metabolism. Family 31 comprises of enzymes that are, or similar to, alpha- galactosidases; cl01320|Residues 13 to 581 of 594 are 74.86 pct identical to residues 213 to 781 of 792 from GenPept.129 : >emb|CAC89695.1| (AJ414145) putative glucosidase [Yersinia pestis] | COG1501(9) | | | |
| 3848 |
|
| Putative transcriptional regulator|helix_turn _helix lactose operon repressor; smart00354|Transcriptional regulators [Transcription]; COG1609|Residues 9 to 364 of 364 are 54.03 pct identical to residues 1 to 359 of 360 from GenPept.129 : >emb|CAC89693.1| (AJ414145) LacI-family regulatory protein [Yersinia pestis] | COG1609(10) | | SM00354(10) | |
| 3858 |
|
| hypothetical protein|Dehydroquinase (DHQase), type II. Dehydroquinase (or 3-dehydroquinate dehydratase) catalyzes the reversible dehydration of 3-dehydroquinate to form 3-dehydroshikimate; cd00466 | | | | |
| 3859 |
|
| putative siderophore biosynthetic enzyme|Siderophore synthetase component [Secondary metabolites biosynthesis, transport, and catabolism]; COG4264|highly similar to Yersinia pestis CO92 YPO1538 | COG4264(11) | | | |
| 3860 |
|
| putative peptidase|Xaa-Pro aminopeptidase [Amino acid transport and metabolism]; COG0006|Creatinase/Prolidase N-terminal domain. This family includes the N-terminal non-catalytic domains from creatinase and prolidase. The exact function of this domain is uncertain; pfam01321 | COG0006(7) | PF01321(6) | | |
| 3861 |
|
| putative adhesin|Autotransporter adhesin [Intracellular trafficking and secretion / Extracellular structures]; COG5295|Haemagglutinin. This short motif is found in invasins and haemagglutinins, normally associated with (pfam05658); pfam05662|YadA-like C-terminal region. This region represents the C-terminal 120 amino acids of a family of surface-exposed bacterial proteins. YadA, an adhesin from Yersinia, was the first member of this family to be characterised. UspA2 from Moraxella was...; pfam03895 | COG5295(9) | PF03895(5), PF05662(2)|PF03895(2) | | |
| 3868 |
|
| hypothetical protein|Enterobacterial putative membrane protein (DUF943). This family consists of several hypothetical putative membrane proteins from Escherichia coli, Yersinia pestis and Salmonella typhi; pfam06092 | | PF06092(11) | | |
| 3870 |
|
| putative transketolase|Transketolase, C-terminal subunit [Carbohydrate transport and metabolism]; COG3958|Transketolase, pyrimidine binding domain. This family includes transketolase enzymes, pyruvate dehydrogenases, and branched chain alpha-keto acid decarboxylases; pfam02779 | COG3958(8) | PF02779(8)|PF02780(8) | | |
| 3919 |
|
| putative urease accessory protein G|Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase [Posttranslational modification, protein turnover, chaperones / Transcription]; COG0378 | COG0378(11) | | | P69993(1) |
| 3920 |
|
| putative urease structural subunit C (alpha)|Urea amidohydrolase (urease) alpha subunit [Amino acid transport and metabolism]; COG0804|Urease alpha-subunit; Urease is a nickel-dependent metalloenzyme that catalyzes the hydrolysis of urea to form ammonia and carbon dioxide. Nickel-dependent ureases are found in bacteria, fungi and plants; cd00375 | COG0804(11) | | | P52313(1) |
| 3921 |
|
| putative urease structural subunit B (beta)|Urease beta-subunit; Urease is a nickel-dependent metalloenzyme that catalyzes the hydrolysis of urea to form ammonia and carbon dioxide. Nickel-dependent ureases are found in bacteria, archaea, fungi and plants; cd00407 | | | | P69991(1) |
| 3925 |
|
| putative carbohydrate kinase|Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB) [Carbohydrate transport and metabolism]; COG1105|2-keto-3-deoxygluconate kinase (KdgK) phosphorylates 2-keto-3-deoxygluconate (KDG) to form 2-keto-3-deoxy-6-phosphogluconate (KDGP); cd01166|Uncharacterized protein conserved in bacteria [Function unknown]; COG3892 | COG3892(6), COG1105(1)|COG3892(1) | | | |
| 3929 |
|
| flagellar biosynthetic protein FliR|Flagellar biosynthesis pathway, component FliR [Cell motility and secretion / Intracellular trafficking and secretion]; COG1684 | COG1684(6) | | | |
| 3930 |
|
| flagellar basal-body rod protein FlgB | COG1815(2) | | | |
| 3931 |
|
| general substrate transport|Sugar phosphate permease [Carbohydrate transport and metabolism]; COG2271|Major Facilitator Superfamily; pfam07690 | COG2271(8) | PF07690(8) | | |
| 3935 |
|
| putative Zn-dependent carboxypeptidase|Zn-dependent carboxypeptidase [Amino acid transport and metabolism]; COG2317|Carboxypeptidase Taq (M32) metallopeptidase; pfam02074 | COG2317(7) | PF02074(8) | | |
| 3937 |
|
| putative zinc-containing alcohol dehydrogenase superfamily|NADPH:quinone reductase and related Zn-dependent oxidoreductases [Energy production and conversion / General function prediction only]; COG0604|Alcohol dehydrogenase GroES-like domain. This is the catalytic domain of alcohol dehydrogenases. Many of them contain an inserted zinc binding domain. This domain has a GroES-like structure; pfam08240|Zinc-binding dehydrogenase; pfam00107 | COG0604(8) | PF08240(8)|PF00107(8) | | |
| 3949 |
|
| putative hemolysin activator protein|POTRA domain, ShlB-type. The POTRA domain (for polypeptide-transport-associated domain) is found towards the N-terminus of ShlB family proteins (pfam03865). ShlB is important in the secretion and activation of the haemolysin ShlA; pfam08479|Haemolysin secretion/activation protein ShlB/FhaC/HecB. This family represents a group of sequences that are related to ShlB from Serratia marcescens; pfam03865 | COG2831(6) | PF08479(10)|PF03865(10) | | |
| 3955 |
|
| putative carbonic anhydrase|Carbonic anhydrases (CA) are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism in which the nucleophilic attack of a zinc-bound hydroxide ion on carbon dioxide is followed by the regeneration of an ac; cd03378 | | | | |
| 3956 |
|
| putative tight adherance operon protein | | PF00437(6) | | |
| 3959 |
|
| hypothetical protein|YCII-related domain. The majority of proteins in this family consist of a single copy of this domain, though it is also found as a repeat. A strongly conserved histidine and a aspartate suggest that the domain has an enzymatic function; pfam03795 | COG2350(7) | PF03795(1) | | |
| 3960 |
|
| hypothetical protein | | | | |
| 3962 |
|
| glucosyl transferase|Glycosyl transferase family 2. Diverse family, transferring sugar from UDP-glucose, UDP-N-acetyl- galactosamine, GDP-mannose or CDP-abequose, to a range of substrates including cellulose, dolichol phosphate and teichoic acids; pfam00535 | | PF00535(8) | | |
| 3974 |
|
| Putative oligogalacturonide lyase|Periplasmic component of the Tol biopolymer transport system [Intracellular trafficking and secretion]; COG0823|Residues 1 to 386 of 390 are 65.02 pct identical to residues 1 to 386 of 388 from SwissProt.40 : >sp|Q59418|OGL_ERWCA OLIGOGALACTURONIDE LYASE | COG0823(9) | | | |
| 3975 |
|
| Hypothetical protein|Coenzyme F390 synthetase [Coenzyme metabolism]; COG1541|Residues 1 to 424 of 428 are 66.03 pct identical to residues 1 to 424 of 428 from GenPept.129 : >emb|CAC90794.1| (AJ414150) putative coenzyme synthetase [Yersinia pestis] | COG1541(6) | | | |
| 3976 |
|
| Putative gumP homolog|Zn-dependent hydrolases, including glyoxylases [General function prediction only]; COG0491|Residues 1 to 268 of 268 are 69.02 pct identical to residues 1 to 268 of 268 from GenPept.129 : >emb|CAC90793.1| (AJ414150) conserved hypothetical protein [Yersinia pestis] | COG1237(5), COG0491(3) | | | |
| 3977 |
|
| Hypothetical protein ybjS|Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; COG0451|3-beta hydroxysteroid dehydrogenase/isomerase family; pfam01073|Escherichia coli K-12 ortholog: b0868; Escherichia coli O157:H7 ortholog: z1102 | COG0451(7) | PF01073(7) | | |
| 4017 |
|
| putative urease structural subunit A (gamma)|Urease gamma-subunit; Urease is a nickel-dependent metalloenzyme that catalyzes the hydrolysis of urea to form ammonia and carbon dioxide. Nickel-dependent ureases are found in bacteria, archaea, fungi and plants; cd00390 | | | | P69995(1) |
| 4018 |
|
| putative acetolactate synthase large subunit|Acetolactate synthase [Amino acid transport and metabolism]; COG3962|Thiamine pyrophosphate enzyme, N-terminal TPP binding domain; pfam02776|Thiamine pyrophosphate enzyme, central domain. The central domain of TPP enzymes contains a 2-fold Rossman fold; pfam00205|Thiamine pyrophosphate (TPP) family, IolD subfamily, TPP-binding module; composed of proteins similar to Rhizobium leguminosarum bv. viciae IolD. IolD plays an important role in myo-inositol catabolism; cd02003 | COG3962(8) | PF02776(8)|PF00205(8) | | |
| 4019 |
|
| putative transcriptional regulator|Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; COG0745|Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; contains; cd00156|Residues 9 to 240 of 241 are 41.52 pct identical to residues 2 to 234 of 238 from GenPept 118 : gi|152259|gb|AAA74221.1| (M38698) lcrB gene product [Rhizobium sp.] | COG0745(10) | | | |
| 4020 |
|
| putative kinase|Adenosine kinase (AK) catalyzes the phosphorylation of ribofuranosyl-containing nucleoside analogues at the 5'-hydroxyl using ATP or GTP as the phosphate donor; cd01168|Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB) [Carbohydrate transport and metabolism]; COG1105|Residues 2 to 327 of 333 are 24.35 pct identical to residues 1 to 316 of 320 from GenPept 118 : gi|2632930|emb|CAB12436.1| (Z99107) similar to fructokinase [Bacillus subtilis] | COG1105(1)|COG0524(1), COG1105(3) | | | |
| 4021 |
|
| putative periplasmic ribose-binding protein of ABC transport system|ABC-type xylose transport system, periplasmic component [Carbohydrate transport and metabolism]; COG4213|Residues 6 to 309 of 313 are 35.04 pct identical to residues 348 to 651 of 651 from GenPept 118 : gi|6714794|emb|CAB66286.1| (AL136519) bifunctional carbohydrate binding and transport protein. [Streptomyces coelicolor A3(2)] | COG4213(2), COG1879(5)|COG4213(5), COG4213(2)|COG1879(2) | PF00532(3) | | |
| 4022 |
|
| putative permease of ribose ABC transport system|Predicted ABC-type sugar transport system, permease component [General function prediction only]; COG4158|Residues 2 to 318 of 324 are 43.78 pct identical to residues 3 to 321 of 322 from GenPept 118 : gi|2636120|emb|CAB15612.1| (Z99122) ribose ABC transporter (permease) [Bacillus subtilis] | COG4158(10) | | | |
| 4026 |
|
| predicted periplasmic chaperone protein|Gram-negative pili assembly chaperone, N-terminal domain. C2 domain-like beta-sandwich fold; pfam00345|putative chaperone; GO_process: protein folding | | PF00345(8)|PF02753(8), PF00345(1) | | |
| 4027 |
|
| predicted outer membrane protein|Fimbrial Usher protein. This protein is involved in biogenesis of gram negative bacterial pili; pfam00577 | COG3188(6) | PF00577(2) | | |
| 4028 |
|
| putative flagellar L-ring protein | | | | Q666C4(1) |
| 4029 |
|
| putative response regulator; hexosephosphate transport|Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; COG2197|Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; contains; cd00156|Bacterial regulatory proteins, luxR family; pfam00196|Residues 1 to 202 of 209 are 49.00 pct identical to residues 1 to 194 of 196 from GenPept 118 : gi|154408|gb|AAA27243.1| (M89480) hexosephosphate utilization protein [Salmonella typhimurium] | COG2197(9) | PF00196(10) | | |
| 4039 |
|
| colicin Js-sensitive receptor protein|Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; COG1629|TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; cd01347|Code: P; COG: COG1629 | COG1629(8) | | | |
| 4040 |
|
| colicin Js-sensitive putative membrane protein|Periplasmic protein TonB, links inner and outer membranes [Cell envelope biogenesis, outer membrane]; COG0810|Code: M; COG: COG0810 | COG0810(8) | | | |
| 4048 |
|
| putative O-antigen biosynthesis protein|Lipid A core - O-antigen ligase and related enzymes [Cell envelope biogenesis, outer membrane]; COG3307|O-Antigen Polymerase. This group of bacterial proteins is involved in the synthesis of O-antigen, a lipopolysaccharide found in the outer membrane in gram-negative bacteria; pfam04932 | COG3307(8) | PF04932(8) | | |
| 4050 |
|
| hypothetical protein|Putative phospholipid-binding domain. This domain is found in a family of osmotic shock protection proteins. It is also found in some Secretins and a group of potential haemolysins. Its likely function is attachment to phospholipid membranes; pfam04972 | | PF04972(8) | | |
| 4051 |
|
| hypothetical protein|Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of substrates, such as, amino acids, peptides, sugars, vitamins and inorganic i; cd00134 | | | | |
| 4052 |
|
| putative AcrB, Cation/multidrug efflux pump|Predicted exporter [General function prediction only]; COG4258 | COG0841(1)|COG4258(1), COG0841(8) | | | |
| 4056 |
|
| putative HlyD family secretion protein|macrolide transporter subunit MacA; PRK11578 | | | | |
| 4061 |
|
| putative D-isomer specific 2-hydroxyacid dehydrogenase family protein|Lactate dehydrogenase and related dehydrogenases [Energy production and conversion / Coenzyme metabolism / General function prediction only]; COG1052|D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain. This domain is inserted into the catalytic domain, the large dehydrogenase and D-lactate dehydrogenase families in SCOP. N-terminal portion of which is represented by family pfam00389; pfam02826 | COG1052(7) | PF02826(7) | | |
| 4123 |
|
| putative helix-turn-helix protein|Transcriptional regulators [Transcription]; COG1737|Helix-turn-helix domain, rpiR family. This domain contains a helix-turn-helix motif. The best characterised member of this family is RpiR, a regulator of the expression of rpiB gene; pfam01418 | COG1737(8) | PF01418(8)|PF01380(8) | | |
| 4124 |
|
| hypothetical protein|Uncharacterized enzyme involved in inositol metabolism [Carbohydrate transport and metabolism]; COG3718 | COG3718(7) | | | |
| 4125 |
|
| putative histidine kinase|HAMP domain; pfam00672|His Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via trans-autophosphorylat; cd00082|Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; cd00075|Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; contains; cd00156|Residues 389 to 752 of 756 are 43.60 pct identical to residues 286 to 663 of 671 from GenPept 118 : gi|5052340|gb|AAD38510.1|AF133262_2 (AF133262) histidine protein kinase-response regulator hybrid protein CvgSY [Pseudomonas syringae pv. syringae] | COG0642(3) | PF00672(10) | | |
| 4127 |
|
| putative fumarylacetoacetate (FAA) hydrolase|2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) [Secondary metabolites biosynthesis, transport, and catabolism]; COG0179|Fumarylacetoacetate (FAA) hydrolase family. This family consists of fumarylacetoacetate (FAA) hydrolase, or fumarylacetoacetate hydrolase (FAH) and it also includes HHDD isomerase/OPET decarboxylase from E. coli strain W; pfam01557 | COG0179(7) | PF01557(7) | | |
| 4128 |
|
| putative ornithine cyclodeaminase|Predicted ornithine cyclodeaminase, mu-crystallin homolog [Amino acid transport and metabolism]; COG2423 | COG2423(7) | | | |
| 4129 |
|
| flagellar basal-body rod protein FlgC|Domain of unknown function (DUF1078). This family consists of a number of C-terminal domains of unknown function; pfam06429 | | PF06429(6) | | |
| 4131 |
|
| conserved hypothetical protein|CRISPR-associated protein (Cas_Csy4). CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) is a widespread family of prokaryotic direct repeats with spacers of unique sequence between consecutive repeats; pfam09618 | | PF09618(7) | | |
| 4134 |
|
| cold shock protein E|Cold-shock DNA-binding domain; pfam00313 | | PF00313(6) | | |
| 4144 |
|
| putative lipoprotein|Membrane-bound lytic murein transglycosylase B [Cell envelope biogenesis, outer membrane]; COG2951 | COG2951(7) | | | |
| 4145 |
|
| putative glutamine-dependent NAD|Predicted amidohydrolase [General function prediction only]; COG0388|NAD+ synthase is a homodimer, which catalyzes the final step in de novo nicotinamide adenine dinucleotide (NAD+) biosynthesis, an amide transfer from either ammonia or glutamine to nicotinic acid adenine dinucleotide (NaAD); cd00553 | COG0388(7) | | | |
| 4146 |
|
| putative AMP-binding enzyme-family protein|Long-chain acyl-CoA synthetases (AMP-forming) [Lipid metabolism]; COG1022 | COG1022(7) | PF00501(7) | | |
| 4147 |
|
| putative 3',5'-cyclic-nucleotide phosphodiesterase|Low-affinity cAMP phosphodiesterase [Signal transduction mechanisms]; COG5212 | COG5212(7) | | | |
| 4148 |
|
| proline iminopeptidase|alpha/beta hydrolase fold. This catalytic domain is found in a very wide range of enzymes; pfam00561 | | PF00561(7) | | |
| 4149 |
|
| putative fimbrial biogenesis protein|Tfp pilus assembly protein PilF [Cell motility and secretion / Intracellular trafficking and secretion]; COG3063|Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi, pl; cd00189 | COG3063(7) | | | |
| 4150 |
|
| conserved hypothetical protein|Uncharacterized protein conserved in bacteria [Function unknown]; COG4517 | COG4517(7) | | | |
| 4151 |
|
| putative two-component system sensor kinase|HAMP domain; pfam00672|His Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via trans-autophosphorylat; cd00082|Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; cd00075 | | PF00672(7) | | |
| 4153 |
|
| putative LysE type translocator|Putative threonine efflux protein [Amino acid transport and metabolism]; COG1280 | COG1280(7) | | | |
| 4154 |
|
| Biotin carboxylase|hypothetical protein; PRK07206|Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain. Phosphoribosylglycinamide synthetase catalyses the second step in the de novo biosynthesis of purine; pfam01071|highly similar to Yersinia pestis CO92 YPO4021 and Yersinia pestis KIM y4042. | | PF01071(6) | | |
| 4155 |
|
| putative carbon-nitrogen hydrolase|Predicted amidohydrolase [General function prediction only]; COG0388 | COG0388(7) | | | |
| 4156 |
|
| conserved hypothetical protein|Peptidylarginine deiminase and related enzymes [Amino acid transport and metabolism]; COG2957 | COG2957(7) | | | Q666N7(1) |
| 4157 |
|
| hypothetical protein|Fic family protein [Function unknown]; COG3177|Fic protein family. This family consists of the Fic (filamentation induced by cAMP) protein and its relatives; pfam02661|HTH domain. This family includes helix-turn-helix domains in a wide variety of proteins; pfam08279|induced in stationary phase, recognized by rpoS, affects cell division | COG3177(8) | PF02661(7), PF02661(1)|PF08279(1) | | |
| 4158 |
|
| putative binding-protein-dependent transport systems inner membrane component|ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; COG0395 | COG0395(8) | | | |
| 4159 |
|
| hypothetical protein|multidrug efflux system subunit MdtA; PRK11556 | COG0845(5) | PF00529(1) | | |
| 4161 |
|
| conserved hypothetical protein|yafU; identified by similarity to GB:CAH22064.1 | | | | |
| 4168 |
|
| hypothetical protein,, | | | | |
| 4171 |
|
| putative glycoprotein|Alpha-galactosidase [Carbohydrate transport and metabolism]; COG3345|Melibiase; pfam02065 | COG3345(7) | PF02065(7) | | |
| 4172 |
|
| hemolysin F|NAD dependent epimerase/dehydratase family. This family of proteins utilise NAD as a cofactor. The proteins in this family use nucleotide-sugar substrates for a variety of chemical reactions; pfam01370|Male sterility protein. This family represents the C-terminal region of the male sterility protein in a number of arabidopsis and drosophila. A sequence-related jojoba acyl CoA reductase is also included; pfam07993 | | PF07993(7), PF01370(1)|PF07993(1) | | |
| 4180 |
|
| putative phage inhibition, colicin resistance and tellurite resistance protein|Uncharacterized proteins involved in stress response, homologs of TerZ and putative cAMP-binding protein CABP1 [Signal transduction mechanisms]; COG2310 | COG2310(9) | | | |
| 4181 |
|
| putative phage inhibition, colicin resistance and tellurite resistance protein|Uncharacterized proteins involved in stress response, homologs of TerZ and putative cAMP-binding protein CABP1 [Signal transduction mechanisms]; COG2310 | COG2310(9) | | | |
| 4182 |
|
| putative phage inhibition, colicin resistance and tellurite resistance protein|Tellurite resistance protein TerB. This family contains the TerB tellurite resistance proteins from a a number of bacteria; pfam05099 | COG3793(6) | PF05099(3) | | |
| 4183 |
|
| putative phage inhibition, colicin resistance and tellurite resistance protein|Uncharacterized proteins involved in stress response, homologs of TerZ and putative cAMP-binding protein CABP1 [Signal transduction mechanisms]; COG2310|Residues 45 to 385 of 385 are 99.70 pct identical to residues 1 to 341 of 341 from GenPept 118 : gi|950679|gb|AAA86847.1| (U59239) putative TerA [Serratia marcescens] | COG2310(9)|COG4110(9) | | | |
| 4184 |
|
| putative phage inhibition, colicin resistance and tellurite resistance protein|Uncharacterized proteins involved in stress response, homologs of TerZ and putative cAMP-binding protein CABP1 [Signal transduction mechanisms]; COG2310 | COG2310(9) | | | |
| 4185 |
|
| putative carbamoyl phosphate synthase large subunit; PRK12767|Residues 180 to 352 of 352 are 99.42 pct identical to residues 1 to 173 of 173 from GenPept 118 : gi|1695870|gb|AAB37124.1| (U59239) unknown [Serratia marcescens] | | PF08443(1) | | |
| 4186 |
|
| Residues 1 to 197 of 380 are 99.49 pct identical to residues 1 to 197 of 197 from GenPept 118 : gi|1695869|gb|AAB37123.1| (U59239) unknown [Serratia marcescens] | | | | |
| 4187 |
|
| mannosyl-3-phosphoglycerate phosphatase; PRK00192|Residues 1 to 167 of 331 are 100.00 pct identical to residues 72 to 238 of 238 from GenPept 118 : gi|1695868|gb|AAB37122.1| (U59239) unknown [Serratia marcescens] | | | | |
| 4188 |
|
| Residues 22 to 354 of 371 are 37.06 pct identical to residues 467 to 810 of 839 from GenPept 118 : gi|8246803|emb|CAB92838.1| (AL356892) hypothetical protein [Streptomyces coelicolor A3(2)] | | | | |
| 4189 |
|
| Citrate lyase beta subunit [Carbohydrate transport and metabolism]; COG2301|Residues 5 to 309 of 318 are 42.39 pct identical to residues 9 to 308 of 310 from GenPept 118 : gi|6460023|gb|AAF11768.1|AE002054_13 (AE002054) hypothetical protein [Deinococcus radiodurans] | COG2301(9) | | | |
| 4190 |
|
| unknown associated with putative tellurite resistance|Predicted transcriptional regulator [Transcription]; COG2378|Residues 1 to 155 of 155 are 99.35 pct identical to residues 1 to 155 of 155 from GenPept 118 : gi|1354147|gb|AAC44736.1| (U49054) terW [Plasmid R478] | COG2378(3) | | | |
| 4226 |
|
| conserved hypothetical protein|CRISPR-associated protein (Cas_Csy3). CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) is a widespread family of prokaryotic direct repeats with spacers of unique sequence between consecutive repeats; pfam09615 | | PF09615(7) | | |
| 4227 |
|
| conserved hypothetical protein|CRISPR-associated protein (Cas_Csy2). CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) is a widespread family of prokaryotic direct repeats with spacers of unique sequence between consecutive repeats; pfam09614 | | PF09614(7) | | |
| 4228 |
|
| conserved hypothetical protein|CRISPR-associated protein (Cas_Csy1). CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) is a widespread family of prokaryotic direct repeats with spacers of unique sequence between consecutive repeats; pfam09611 | | PF09611(7) | | |
| 4229 |
|
| conserved hypothetical protein|CRISPR-associated protein Cas1 [Defense mechanisms]; COG1518 | COG1518(7) | | | |
| 4238 |
|
| F17 fimbrial protein precursor|Fimbrial protein; pfam00419 | COG3539(6) | PF00419(3) | | |
| 4239 |
|
| putative regulator|Transcriptional regulators [Transcription]; COG1737|Helix-turn-helix domain, rpiR family. This domain contains a helix-turn-helix motif. The best characterised member of this family is RpiR, a regulator of the expression of rpiB gene; pfam01418 | COG1737(7) | PF01418(7)|PF01380(7) | | |
| 4240 |
|
| putative lysophospholipase|Esterase/lipase [General function prediction only]; COG1647 | COG2267(5)|COG1647(5), COG0657(1)|COG1647(1), COG1647(1) | | | |
| 4241 |
|
| putative oxidoreductase|Predicted dehydrogenases and related proteins [General function prediction only]; COG0673|Oxidoreductase family, NAD-binding Rossmann fold. This family of enzymes utilise NADP or NAD. This family is called the GFO/IDH/MOCA family in swiss-prot; pfam01408 | COG0673(8) | PF01408(8) | | |
| 4242 |
|
| putative ABC transporter, permease protein|Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components [Carbohydrate transport and metabolism]; COG1172 | COG1172(8) | | | |
| 4243 |
|
| putative periplasmic binding protein/LacI transcriptional regulator|ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; COG1879 | COG1879(8) | | | |
| 4244 |
|
| hypothetical protein|Uncharacterized conserved protein [Function unknown]; COG5276 | COG5276(8) | | | |
| 4250 |
|
| flagellar biosynthetic protein FlhB|Flagellar biosynthesis pathway, component FlhB [Cell motility and secretion / Intracellular trafficking and secretion]; cl00975|FlhB HrpN YscU SpaS Family. This family includes the following members: FlhB, HrpN, YscU, SpaS, HrcU SsaU and YopU. All of these proteins export peptides using the type III secretion system. The peptides exported are quite diverse; pfam01312 | | PF01312(6) | | |
| 4251 |
|
| Flagellar biosynthesis/type III secretory pathway protein|Bacterial export proteins, family 3. This family includes the following members; FliQ, MopD, HrcS, Hrp, YopS and SpaQ All of these members export proteins, that do not possess signal peptides, through the membrane. Although the proteins that these...; cl00867 | | | | |
| 4252 |
|
| flagellar biosynthetic protein FliP | | | | |
| 4253 |
|
| flagellar switch protein|Surface presentation of antigens (SPOA) protein; cl00819|highly similar to Yersinia pestis CO92 fliN and Yersinia pestis KIM y3468. Contains Flagellar motor switch FliN protein (Interpro|IPR001172, (GO:0001539), (GO:0003774), (GO:0009425)). Contains Surface presentation of antigens (SPOA) protein (Interpro|IPR001543). Contains Type III secretion system outer membrane O protein (Interpro|IPR003283, (GO:0009306), (GO:0015448)) | | | | |
| 4254 |
|
| sigma-54 transcriptional regulatory protein|phage shock protein operon transcriptional activator; PRK11608|ABC (ATP-binding cassette) transporter nucleotide-binding domain; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The...; cl09099|Bacterial regulatory protein, Fis family; cl01091|highly similar to Yersinia pestis CO92 YPO0712 and Yersinia pestis KIM atoC. Contains CbxX/CfqX superfamily (Interpro|IPR000641, (GO:0005524)). Contains Beta and gamma crystallin (Interpro|IPR001064). Contains Sigma-54 factor interaction domain (Interpro|IPR002078, (GO:0000160), (GO:0003677), (GO:0006355)). Contains Helix-turn-helix, Fis-type (Interpro|IPR002197, (GO:0006355)). Contains AAA ATPase (Interpro|IPR003593, (GO:0000166)) | | | | |
| 4255 |
|
| flagellar hook-basal body complex protein FliE|Flagellar hook-basal body protein [Cell motility and secretion / Intracellular trafficking and secretion]; COG1677 | COG1677(6) | | | |
| 4256 |
|
| putative flagellar M-ring protein|flagellar MS-ring protein; PRK07193|Secretory protein of YscJ/FliF family. This family includes proteins that are related to the YscJ lipoprotein, and the amino terminus of FliF, the flageller M-ring protein; pfam01514 | | PF01514(6)|PF08345(6) | | |
| 4257 |
|
| Flagellar motor switch protein|FliG C-terminal domain. FliG is a component of the flageller rotor, present in about 25 copies per flagellum. This domain functions specifically in motor rotation; cl03323|highly similar to Yersinia pestis KIM y3463. Contains Flagellar motor switch protein FliG (Interpro|IPR000090, (GO:0001539), (GO:0003774), (GO:0009288)) | COG1536(5) | | | |
| 4258 |
|
| flagellar assembly protein FliH|Flagellar biosynthesis/type III secretory pathway protein [Cell motility and secretion / Intracellular trafficking and secretion]; COG1317 | COG1317(5) | | | |
| 4259 |
|
| Membrane proteins related to metalloendopeptidases|highly similar to Yersinia pestis KIM y3460, | | | | |
| 4260 |
|
| hypothetical protein|highly similar to Yersinia pestis KIM y3459 | | | | |
| 4261 |
|
| putative flagellar protein|flagellar basal body P-ring biosynthesis protein FlgA; PRK06804|highly similar to Yersinia pestis KIM lfgA. Contains Flageller protein FlgA (Interpro|IPR004924, Cellular Component: flagellum (sensu Bacteria) (GO:0009288), (GO:0030288)) | | | | |
| 4262 |
|
| basal-body rod modification protein FlgD|flagellar basal body rod modification protein; PRK09619|highly similar to Yersinia pestis CO92 flgD and Yersinia pestis KIM lfgD. Contains Aldehyde dehydrogenase (Interpro|IPR002086, (GO:0008152), (GO:0016491)). Contains Flagellar hook capping protein (Interpro|IPR005648). Contains Flagellar hook capping protein (Interpro|IPR005648) | | | | |
| 4263 |
|
| flagellar hook protein FlgE|Flagellar basal body protein FlaE. This family consists of several bacterial FlaE flagellar proteins. These proteins are part of the flageller basal body rod complex; pfam07559 | | PF07559(6)|PF06429(6) | | |
| 4264 |
|
| hypothetical protein|highly similar to Yersinia pestis KIM y3444,, | | | | |
| 4270 |
|
| hypothetical protein | | | | |
| 4271 |
|
| putative peptidase C15, pyroglutamyl peptidase I|Pyroglutamyl peptidase (PGP) type I, also known as pyrrolidone carboxyl peptidase (pcp) type I: Enzymes responsible for cleaving pyroglutamate (pGlu) from the N-terminal end of specialized proteins; cd00501 | | | | Q667T6(1) |
| 4272 |
|
| Hypothetical protein|Residues 1 to 173 of 180 are 37.35 pct identical to residues 1 to 174 of 178 from GenPept.129 : >emb|CAC89258.1| (AJ414142) hypothetical protein [Yersinia pestis] | | | | |
| 4276 |
|
| putative ABC-type transport system, ATPase component|NrtD and SsuB are the ATP-binding subunits of the bacterial ABC-type nitrate and sulfonate transport systems, respectively. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars...; cd03293 | COG1116(5) | | | |
| 4277 |
|
| hypothetical protein|Zn-dependent hydrolases, including glyoxylases [General function prediction only]; COG0491 | COG0491(7) | | | |
| 4278 |
|
| putative transcriptional regulator (LysR family)|predicted DNA-binding transcriptional regulator, efflux system; PRK10632|Bacterial regulatory helix-turn-helix protein, lysR family; pfam00126|LysR substrate binding domain. The structure of this domain is known and is similar to the periplasmic binding proteins; pfam03466 | | PF00126(8)|PF03466(8) | | |
| 4279 |
|
| putative ABC-type metal ion transport system, periplasmic component/surface antigen | COG1464(8) | | | |
| 4280 |
|
| putative amino acid transport protein (ABC superfamily, membrane) | COG0765(8) | | | |
| 4281 |
|
| glutamate/aspartate transport protein (ABC superfamily, membrane)|ABC-type amino acid transport system, permease component [Amino acid transport and metabolism]; COG0765 | COG0765(8) | | | |
| 4282 |
|
| cysteine transport protein (ABC superfamily, peri_bind)|Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of substrates, such as, amino acids, peptides, sugars, vitamins and inorganic i; cd00134 | | | | |
| 4283 |
|
| high-affinity branched-chain amino acid transport protein (ABC superfamily, peri_bind) | COG0683(8) | PF01094(8) | | |
| 4284 |
|
| high-affinity branched-chain amino acid transport protein (ABC superfamily, membrane) | COG0559(2), COG1413(6)|COG0559(6) | | | |
| 4285 |
|
| high-affinity branched-chain amino acid transport | COG4177(8) | | | |
| 4286 |
|
| ATP-binding component of high-affinity branched-chain amino acid transport system|The Mj1267/LivG ABC transporter subfamily is involved in the transport of the hydrophobic amino acids leucine, isoleucine and valine. MJ1267 is a branched-chain amino acid transporter with 29% similarity to both the LivF and LivG components of the E; cd03219 | | | | |
| 4287 |
|
| ATP-binding component of leucine transport|LivF (TM1139) is part of the LIV-I bacterial ABC-type two-component transport system that imports neutral, branched-chain amino acids. The E; cd03224 | COG0410(7) | | | |
| 4295 |
|
| putative MgtE integral membrane region|MgtE intracellular domain. This domain is found in eubacterial magnesium transporters of the MgtE family pfam01769. This region of similarity is presumed to be an intracellular domain, that may be involved in magnesium binding; pfam03448|Mg/Co/Ni transporter MgtE (contains CBS domain) [Inorganic ion transport and metabolism]; COG2239|This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains in association with the ABC transporter OpuCA; cd04583 | COG2239(7) | PF03448(8)|PF01769(8) | | |
| 4297 |
|
| putative inner membrane protein|Type VI protein secretion system component VasK [Intracellular trafficking, secretion, and vesicular transport]; COG3523|ImcF-related; pfam06761|Protein of unknown function (DUF1215). This family represents a conserved region situated towards the C-terminal end of several hypothetical bacterial proteins of unknown function; pfam06744 | COG3523(9) | PF06761(9)|PF06744(9) | | |
| 4302 |
|
| ABC-type multidrug/protein/lipid transport system, ATPase component|Uncharacterized protein conserved in bacteria [Function unknown]; COG4253|highly similar to Yersinia pestis CO92 YPO0967 and Yersinia pestis KIM y3354 | COG4253(9) | | | |
| 4306 |
|
| putative ABC transport protein|ABC transporter transmembrane region. This family represents a unit of six transmembrane helices. Many members of the ABC transporter family (pfam00005) have two such regions; pfam00664|ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components [Posttranslational modification, protein turnover, chaperones]; COG5265 | COG5265(7) | PF00664(7) | | |
| 4307 |
|
| putative exported protein|Uncharacterized conserved protein [Function unknown]; COG1704|highly similar to Yersinia pestis CO92 lemA | COG1704(6) | | | |
| 4308 |
|
| putative aminotransferase|aspartate aminotransferase; PRK08443|Aspartate/tyrosine/aromatic aminotransferase [Amino acid transport and metabolism]; COG0436|highly similar to Yersinia pestis CO92 YPO0623 and Yersinia pestis KIM y3555. Contains 1-aminocyclopropane-1-carboxylate synthase (Interpro|IPR001176, (GO:0009058), (GO:0016847)). Contains Aminotransferase, class-I (Interpro|IPR004838, (GO:0009058)). Contains Aminotransferase, class I and II (Interpro|IPR004839, (GO:0009058)) | COG0436(6) | | | |
| 4309 |
|
| putative membrane protein|Predicted small integral membrane protein [Function unknown]; COG5472|highly similar to Yersinia pestis CO92 YPO0899 and Yersinia pestis KIM y3284. | COG5472(6) | | | |
| 4310 |
|
| putative membrane protein|Predicted Co/Zn/Cd cation transporters [Inorganic ion transport and metabolism]; COG3965 | COG3965(6) | | | |
| 4311 |
|
| putative lipoprotein|Patatin-like phospholipase. This family consists of various patatin glycoproteins from plants. The patatin protein accounts for up to 40% of the total soluble protein in potato tubers; pfam01734|highly similar to Yersinia pestis CO92 YPO1689 and Yersinia pestis KIM y1852. Contains Patatin (Interpro|IPR002641, (GO:0045735)) | | PF01734(6) | | |
| 4312 |
|
| putative Filamentous haemagglutinin|haemagglutination activity domain. This domain is suggested to be a carbohydrate- dependent haemagglutination activity site. It is found in a range of haemagglutinins and haemolysins; pfam05860 | | PF05860(8) | | |
| 4313 |
|
| putative ABC transporter periplasmic binding protein|ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; COG1653|Bacterial extracellular solute-binding protein. This family also includes the bacterial extracellular solute-binding protein family POTD/POTF; pfam01547 | COG1653(7) | PF01547(7) | | |
| 4314 |
|
| putative inner membrane permease of oligogalacturonide ABC transporter|ABC-type sugar transport systems, permease components [Carbohydrate transport and metabolism]; COG1175 | COG1175(8) | | | |
| 4315 |
|
| probable outer membrane usher protein|P pilus assembly protein, porin PapC [Cell motility and secretion / Intracellular trafficking and secretion]; COG3188 | COG3188(7) | | | |
| 4316 |
|
| putative membrane protein|Uncharacterized secreted protein [Function unknown]; COG5430 | COG5430(7) | | | |
| 4317 |
|
| putative inner membrane permease of ABC transporter|ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism]; COG1177 | COG1177(5), COG1177(1)|COG1178(1), COG1178(1) | | | |
| 4318 |
|
| hypothetical protein|Uncharacterized conserved protein [Function unknown]; COG4628 | COG4628(8) | | | |
| 4319 |
|
| putative acyltransferase|Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins; pfam00583 | | PF00583(8) | | |
| 4321 |
|
| putative periplasmic binding protein|ABC-type Fe3+-hydroxamate transport system, periplasmic component [Inorganic ion transport and metabolism]; COG0614|Periplasmic binding protein TroA_f. These proteins are predicted to function as initial receptors in the ABC metal ion uptake in eubacteria and archaea; cd01139 | COG0614(8) | | | |
| 4323 |
|
| conserved hypothetical protein|Type VI protein secretion system component Hcp (secreted cytotoxin) [Intracellular trafficking, secretion, and vesicular transport]; COG3157 | COG3157(8) | PF05638(1) | | |
| 4327 |
|
| hypothetical protein|Uncharacterized conserved protein [Function unknown]; COG5460 | COG5460(8) | | | |
| 4329 |
|
| conserved exported protein | | | | |
| 4395 |
|
| hypothetical protein|CRISPR-associated helicase Cas3 [Defense mechanisms]; COG1203,, | COG1203(7) | | | |
| 4412 |
|
| hypothetical protein|Uncharacterized conserved protein, contains double-stranded beta-helix domain [Function unknown]; COG1917 | COG1917(6) | | | |
| 4416 |
|
| putative C4-dicarboxylate transporter, small subunit|TRAP-type C4-dicarboxylate transport system, small permease component [Carbohydrate transport and metabolism]; COG3090 | COG3090(7) | | | |
| 4418 |
|
| putative carboxymuconolactone decarboxylase|Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit [Function unknown]; COG0599 | COG0599(8) | | | |
| 4420 |
|
| Flagellar motor switch protein|highly similar to Yersinia pestis KIM y3467. Contains Flagellar motor switch FliN protein (Interpro|IPR001172, (GO:0001539), (GO:0003774), (GO:0009425)) | | | | |
| 4421 |
|
| flagellar basal-body rod protein FlgG|Domain of unknown function (DUF1078). This family consists of a number of C-terminal domains of unknown function. This domain seems to be specific to flagellar basal-body rod and flagellar hook proteins in which pfam00460 is often present at the...; pfam06429 | | PF00460(6)|PF06429(6) | | |
| 4422 |
|
| flagellar protein FlgJ|peptidoglycan hydrolase; PRK12708|highly similar to Yersinia pestis CO92 flgJ and Yersinia pestis KIM y3447. Contains Flagellar protein FlgJ (Interpro|IPR000423, (GO:0001539), (GO:0009288)). Contains Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase (Interpro|IPR002901, (GO:0009253)) | | | | |
| 4423 |
|
| putative flagellar hook-associated protein|Domain of unknown function (DUF1078). This family consists of a number of C-terminal domains of unknown function; pfam06429 | | PF06429(6) | | |
| 4425 |
|
| conserved hypothetical protein|Predicted Zn-dependent hydrolases of the beta-lactamase fold [General function prediction only]; COG2220 | COG2220(7) | | | |
| 4426 |
|
| putative membrane protein | COG3819(7) | | | |
| 4427 |
|
| putative membrane protein | COG3817(7) | | | |
| 4429 |
|
| Na+-translocating NADH-quinone reductase subunit C|Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrC [Energy production and conversion]; COG2869 | COG2869(7) | | | |
| 4430 |
|
| putative membrane protein|ABC-type antimicrobial peptide transport system, permease component [Defense mechanisms]; COG0577|Predicted permease. This is a family of predicted permeases and hypothetical transmembrane proteins; pfam02687 | COG0577(6) | PF02687(6) | | |
| 4435 |
|
| acetyltransferase|Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis]; COG1670 | COG1670(7) | | | |
| 4438 |
|
| conserved hypothetical protein | | | | |
| 4449 |
|
| D-arabinitol dehydrogenase|Mannitol dehydrogenase Rossmann domain; pfam01232|Mannitol-1-phosphate/altronate dehydrogenases [Carbohydrate transport and metabolism]; COG0246 | COG0246(7) | PF01232(7)|PF08125(7) | | |
| 4450 |
|
| putative transcriptional regulator, sorC family|Transcriptional regulator, contains sigma factor-related N-terminal domain [Transcription]; COG2390|Putative sugar-binding domain. This probable domain is found in bacterial transcriptional regulators such as DeoR and SorC. These proteins have an amino-terminal helix-turn-helix pfam00325 that binds to DNA; pfam04198 | COG2390(7) | PF04198(7) | | |
| 4452 |
|
| orf, conserved hypothetical protein|Flp pilus assembly protein, protease CpaA [Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; COG4960 | COG4960(8) | | | |
| 4454 |
|
| putative exported protein|Enterobacterial putative membrane protein (DUF943). This family consists of several hypothetical putative membrane proteins from Escherichia coli, Yersinia pestis and Salmonella typhi; pfam06092 | | PF06092(8) | | |
| 4455 |
|
| hypothetical protein|similar to Salmonella typhi CT18 hypothetical protein | | | | |
| 4457 |
|
| putative AraC-family regulatory protein|Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain [Transcription]; COG4977|Bacterial regulatory helix-turn-helix proteins, AraC family; pfam00165 | COG4977(7) | PF00165(7) | | |
| 4461 |
|
| putative membrane protein|Integral membrane protein DUF6. This family includes many hypothetical membrane proteins of unknown function. Many of the proteins contain two copies of the aligned region; pfam00892 | | PF00892(7) | | |
| 4463 |
|
| putative chitin binding protein|Uncharacterized protein conserved in bacteria [Function unknown]; COG3397|Similar to Vibrio cholerae putative chitinase VCA0811 SWALL:Q9KLD5 (EMBL:AE004409) (485 aa) fasta scores: E(): 6.4e-53, 36.94 38d in 498 aa. N-terminus is similar to the N-terminal region of Serratia marcescens chitinase precursor SWALL:Q59930 (EMBL:L38484) (227 aa) fasta scores: E(): 6.4e-14, 34.87 38d in 195 aa | COG3397(7) | PF03067(7) | SM00089(6) | |
| 4464 |
|
| putative dicarboxylic acid hydrolase|Predicted metal-dependent hydrolase of the TIM-barrel fold [General function prediction only]; COG3618|2-pyrone-4,6-dicarboxylic acid (PDC) hydrolase hydrolyzes PDC to yield 4-oxalomesaconic acid (OMA) or its tautomer, 4-carboxy-2-hydroxymuconic acid (CHM). This reaction is part of the protocatechuate (PCA) 4,5-cleavage pathway; cd01311|highly similar to Yersinia pestis CO92 YPO1933 and Yersinia pestis KIM y2378. Contains Amidohydrolase 2 (Interpro|IPR006992) | COG3618(5) | | | |
| 4467 |
|
| putative regulator for leucine (or lrp) regulon and high-affinity branched-chain amino acid transport system|Transcriptional regulators [Transcription]; COG1522|helix_turn_helix ASNC type; AsnC: an autogenously regulated activator of asparagine synthetase A transcription in Escherichia coli); smart00344 | COG1522(7) | | SM00344(8) | |
| 4468 |
|
| hypothetical protein|Uncharacterised ACR, YfiH family COG1496; cl00650 | COG1496(8) | | | |
| 4469 |
|
| putative 4-oxalocrotonate tautomerase|4-Oxalocrotonate Tautomerase: Catalyzes the isomerization of unsaturated ketones. The structure is a homohexamer that is arranged as a trimer of dimers. The hexamer contains six active sites, each formed by residues from three monomers, two from one...; cl00235 | | | | |
| 4470 |
|
| putative polysaccharide deacetylase|Predicted xylanase/chitin deacetylase [Carbohydrate transport and metabolism]; COG0726|Polysaccharide deacetylase. This domain is found in polysaccharide deacetylase. This family of polysaccharide deacetylases includes NodB (nodulation protein B from Rhizobium) which is a chitooligosaccharide deacetylase; pfam01522 | COG0726(5) | PF01522(5) | | |
| 4471 |
|
| hypothetical protein|Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; COG0697 | COG0697(8) | PF00892(8) | | |
| 4472 |
|
| deoxyribose-phosphate aldolase|2-deoxyribose-5-phosphate aldolase (DERA) of the DeoC family. DERA belongs to the class I aldolases and catalyzes a reversible aldol reaction between acetaldehyde and glyceraldehyde 3-phosphate to generate 2-deoxyribose 5-phosphate; cd00959 | | | | Q66CP8(1) |
| 4473 |
|
| putative 2OG-Fe(II) oxygenase|Isopenicillin N synthase and related dioxygenases [General function prediction only]; COG3491|2OG-Fe(II) oxygenase superfamily. This family contains members of the 2-oxoglutarate (2OG) and Fe(II)-dependent oxygenase superfamily. This family includes the C-terminal of prolyl 4-hydroxylase alpha subunit. The holoenzyme has the activity EC:1.14.11; pfam03171 | COG3491(8) | PF03171(8) | | |
| 4474 |
|
| D- and L-methionine transport protein (ABC superfamily, atp_bind)|ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; COG1126|MetN (also known as YusC) is an ABC-type transporter encoded by metN of the metNPQ operon in Bacillus subtilis that is involved in methionine transport. Other members of this system include the MetP permease and the MetQ substrate binding protein; cd03258 | COG1135(7), COG1126(1) | PF09383(7) | | |
| 4475 |
|
| putative binding-protein-dependent transport systems inner membrane componen|ABC-type metal ion transport system, permease component [Inorganic ion transport and metabolism]; COG2011 | COG2011(8) | | | |
| 4476 |
|
| hypothetical protein|conserved inner membrane protein; PRK10847 | COG0586(5) | | | |
| 4477 |
|
| anaerobic C4-dicarboxylate transporter|Protein tyrosine/serine phosphatase [Signal transduction mechanisms]; COG2365 | COG2365(8) | | | |
| 4478 |
|
| D-ribose periplasmic binding protein|ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; COG1879 | COG1879(5)|COG4213(5), COG4213(3)|COG1879(3) | | | |
| 4479 |
|
| hypothetical protein|Predicted periplasmic lipoprotein [General function prediction only]; COG5618 | COG5618(8) | | | |
| 4480 |
|
| putative bacterial inner-membrane translocator|Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components [Carbohydrate transport and metabolism]; COG1172 | COG1172(8) | | | |
| 4481 |
|
| putative sugar-binding region|Transcriptional regulator, contains sigma factor-related N-terminal domain [Transcription]; COG2390|MarR family. The Mar proteins are involved in the multiple antibiotic resistance, a non-specific resistance system. The expression of the mar operon is controlled by a repressor, MarR. A large number of compounds induce transcription of the mar operon; pfam01047|Putative sugar-binding domain. This probable domain is found in bacterial transcriptional regulators such as DeoR and SorC. These proteins have an amino-terminal helix-turn-helix pfam00325 that binds to DNA; pfam04198 | COG2390(8) | PF01047(8)|PF04198(8) | | |
| 4482 |
|
| putative L-fucose isomerase, C-terminal|L-fucose isomerase and related proteins [Carbohydrate transport and metabolism]; COG2407|L-fucose isomerase (FucIase) and L-arabinose isomerase (AI) family; composed of FucIase, AI and similar proteins; cd00578 | COG2407(6) | | | |
| 4483 |
|
| maltose transport protein (ABC superfamily, membrane)|ABC-type sugar transport systems, permease components [Carbohydrate transport and metabolism]; COG1175 | COG1175(1) | | | |
| 4484 |
|
| periplasmic maltose-binding protein|Maltose-binding periplasmic proteins/domains [Carbohydrate transport and metabolism]; COG2182 | COG2182(7) | PF01547(6) | | |
| 4485 |
|
| membrane channel protein component of Pn transporter|ABC-type phosphate/phosphonate transport system, permease component [Inorganic ion transport and metabolism]; COG3639 | COG3639(8) | | | |
| 4486 |
|
| hypothetical protein|Glycerophosphoryl diester phosphodiesterase [Energy production and conversion]; COG0584|Glycerophosphoryl diester phosphodiesterase family. E. coli has two sequence related isozymes of glycerophosphoryl diester phosphodiesterase (GDPD) - periplasmic and cytosolic; pfam03009 | COG0584(8) | PF03009(8) | | |
| 4487 |
|
| Na-translocating NADH ubiquinone oxidoreductase, beta chain|Na(+)-translocating NADH-quinone reductase subunit F; PRK05464|Oxidoreductase FAD-binding domain; pfam00970|Oxidoreductase NAD-binding domain. Xanthine dehydrogenases, that also bind FAD/NAD, have essentially no similarity; pfam00175 | | PF00970(8)|PF00175(8) | | |
| 4488 |
|
| Na(+)-translocating NADH-quinone reductase subunit E | | | | |
| 4489 |
|
| Na(+)-translocating NADH-quinone reductase, chain D | | | | |
| 4490 |
|
| Na(+)-translocating NADH-quinone reductase, chain B | | | | |
| 4491 |
|
| NADH-ubiquinone oxidoreductase subunit A|Na(+)-translocating NADH-quinone reductase subunit A; PRK05352 | | | | |
| 4492 |
|
| conserved hypothetical protein|RIO kinase family; RIO1, RIO3 and similar proteins, catalytic domain; cd05145 | | | | |
| 4493 |
|
| 8-amino-7-oxononanoate synthase|Glutamate decarboxylase and related PLP-dependent proteins [Amino acid transport and metabolism]; COG0076|Pyridoxal-dependent decarboxylase conserved domain; pfam00282 | COG0076(7) | PF00282(7) | | |
| 4494 |
|
| putative membrane protein|Predicted O-acyltransferase [General function prediction only]; COG3274 | COG3274(7) | | | |
| 4495 |
|
| putative chaperone protein|P pilus assembly protein, chaperone PapD [Cell motility and secretion / Intracellular trafficking and secretion]; COG3121|Gram-negative pili assembly chaperone, N-terminal domain. C2 domain-like beta-sandwich fold; pfam00345 | COG3121(6) | PF00345(6) | | |
| 4496 |
|
| putative exported protein|Uncharacterized conserved protein, contains double-stranded beta-helix domain [Function unknown]; COG1917|No significant database matches to the full length CDS. N-terminus is similar to the N-terminal region of Yersinia pestis putative exported protein YPO1998 SWALL:Q8ZEZ8 (EMBL:AJ414151) (156 aa) fasta scores: E(): 4.8e-10, 41.59 38d in 113 aa. C-terminus is similar to an internal region of Brucella melitensis transcriptional regulator BMEII0800 SWALL:Q8YBT6 (EMBL:AE009714) (159 aa) fasta scores: E(): 5.3e-13, 55.55 38d in 81 aa | COG1917(7) | | | |
| 4497 |
|
| conserved hypothetical protein | COG1359(7) | | | |
| 4498 |
|
| putative membrane protein|PAP2_like_6 proteins. PAP2 is a super-family of phosphatases and haloperoxidases. This subgroup, which mainly contains bacterial proteins, lacks functional characterization and may act as a membrane-associated lipid phosphatase; cd03396 | | | | |
| 4499 |
|
| putative amino acid transporter|ABC-type branched-chain amino acid transport systems, ATPase component [Amino acid transport and metabolism]; COG0410|LivF (TM1139) is part of the LIV-I bacterial ABC-type two-component transport system that imports neutral, branched-chain amino acids. The E; cd03224 | COG0410(1) | | | |
| 4500 |
|
| putative transcriptional regulators|Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; cd00093 | | | | |
| 4503 |
|
| putative surface-exposed protein|Hemolysin activation/secretion protein [Intracellular trafficking and secretion]; COG2831|POTRA domain, ShlB-type. The POTRA domain (for polypeptide-transport-associated domain) is found towards the N-terminus of ShlB family proteins (pfam03865). ShlB is important in the secretion and activation of the haemolysin ShlA; pfam08479 | COG2831(7) | PF08479(7) | | |
| 4504 |
|
| putative accessory processing protein|Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones]; COG3914 | COG3914(7) | | | |
| 4507 |
|
| hypothetical urea transporter|Urea transporter [Amino acid transport and metabolism]; COG4413 | COG4413(8) | | | |
| 4516 |
|
| putative secretion protein|Bacterial chaperone lipoprotein (PulS_OutS); pfam09691|Similar to Erwinia chrysanthemi OutS protein precursor SWALL:OUTS_ERWCH (SWALL:Q01567) (133 aa) fasta scores: E(): 2.7e-07, 34.16 38d in 120 aa, and to Klebsiella pneumoniae pullulanase secretion protein PulS SWALL:PULS_KLEPN (SWALL:P20440) (125 aa) fasta scores: E(): 1e-07, 31.09 38d in 119 aa | | PF09691(7) | | |
| 4528 |
|
| unknown protein encoded by prophage CP-933N|CAAX amino terminal protease family. Members of this family are probably proteases (after a prenyl group is attached to the Cys residue in the C-terminal CAAX motif of a protein, the AAX tripeptide is removed by one of the CAAX prenyl proteases); pfam02517|Residues 129 to 256 of 274 are 30.34 pct identical to residues 17 to 154 of 189 from GenPept 118 : gi|1146201|gb|AAC83948.1| (L47648) putative [Bacillus subtilis] | | PF02517(8) | | |
| 4529 |
|
| Residues 7 to 444 of 444 are 34.58 pct identical to residues 25 to 449 of 449 from GenPept 118 : gi|4106627|emb|CAA21382.1| (AL031866) ORF59, len=449 aa, some similarity with pilin, Haemophilus influenzae hifA, (213 aa), 27.8% identity in 187 aa overlap | | | | |
| 4559 |
|
| e14 prophage; predicted protein|Caudovirales tail fibre assembly protein. This family contains bacterial and phage tail fibre assembly proteins. E.coli contains several members of this family although the function of these proteins is uncertain; pfam02413 | | PF02413(9) | | |
| 4595 |
|
| hypothetical protein|orf, | | | | |
| 4596 |
|
| putative sugar isomerase|Transcriptional regulators [Transcription]; COG1737|Helix-turn-helix domain, rpiR family. This domain contains a helix-turn-helix motif. The best characterised member of this family is RpiR, a regulator of the expression of rpiB gene; pfam01418 | COG1737(7) | PF01418(7)|PF01380(7) | | |
| 4612 |
|
| putative exported protein|Uncharacterized protein probably involved in high-affinity Fe2+ transport [Inorganic ion transport and metabolism]; COG3470 | COG3470(6) | | | |
| 4613 |
|
| putative membrane protein | COG4393(6)|COG3350(6) | | | |
| 4614 |
|
| ABC transporter, ATP-binding protein|ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; COG1136|This family is comprised of MJ0796 ATP-binding cassette, macrolide-specific ABC-type efflux carrier (MacAB), and proteins involved in cell division (FtsE), and release of liporoteins from the cytoplasmic membrane (LolCDE); cd03255 | COG1136(6) | | | |
| 4615 |
|
| putative thioredoxin|TlpA-like family; composed of TlpA, ResA, DsbE and similar proteins. TlpA, ResA and DsbE are bacterial protein disulfide reductases with important roles in cytochrome maturation; cd02966 | | | | |
| 4618 |
|
| putative bacteriophage protein | | | | |
| 4625 |
|
| ribulokinase|Ribulose kinase [Energy production and conversion]; COG1069|FGGY family of carbohydrate kinases, N-terminal domain. This domain adopts a ribonuclease H-like fold and is structurally related to the C-terminal domain; pfam00370 | COG1069(7) | PF00370(7)|PF02782(7) | | |
| 4629 |
|
| putative bacteriophage protein|Mu-like prophage DNA circulation protein [General function prediction only]; COG4228|highly similar to Yersinia pestis CO92 YPO1246 and Yersinia pestis KIM y2941 | COG4228(6) | | | |
| 4630 |
|
| putative exported protein|highly similar to Yersinia pestis CO92 YPO1886 and Yersinia pestis KIM y2423, | | | | |
| 4631 |
|
| hypothetical protein|highly similar to Yersinia pestis CO92 YPO1887 and Yersinia pestis KIM y2422,,, | | | | |
| 4632 |
|
| putative insecticial toxin|Salmonella virulence plasmid 28.1kDa A protein; pfam03538|highly similar to Yersinia pestis CO92 YPO3681 and Yersinia pestis KIM tcaA1. Contains ATP/GTP-binding site motif A (P-loop) (Interpro|IPR001687, (GO:0005524)) | | PF03538(6) | | |
| 4633 |
|
| conserved hypothetical protein|Uncharacterized paraquat-inducible protein B [Function unknown]; COG3007 | COG3007(7) | | | Q663S5(1) |
| 4634 |
|
| pyridoxal-phosphate dependent enzyme|hypothetical protein; PRK06815 | | | | |
| 4635 |
|
| conserved hypothetical protein|Predicted transcriptional regulator [Transcription]; COG2345 | COG2345(7) | | | |
| 4636 |
|
| putative exported protein|F5/8 type C domain. This domain is also known as the discoidin (DS) domain family; pfam00754 | | PF00754(7) | | |
| 4637 |
|
| metalloprotease|Zinc-dependent metalloprotease, serralysin_like subfamily. Serralysins and related proteases are important virulence factors in pathogenic bacteria; cd04277|Peptidase M10 serralysin C terminal. Serralysins are peptidases related to mammalian matrix metallopeptidases (MMPs); pfam08548 | | PF08548(7) | | |
| 4638 |
|
| conserved hypothetical protein|Tfp pilus assembly protein, ATPase PilM [Cell motility and secretion / Intracellular trafficking and secretion]; COG4972 | COG4972(7) | | | |
| 4639 |
|
| Putative membrane protein|Tfp pilus assembly protein PilN [Cell motility and secretion / Intracellular trafficking and secretion]; COG3166|Similar to Yersinia pestis putative membrane protein ypo0147 SWALL:Q8ZJG1 (EMBL:AJ414141) (201 aa) fasta scores: E(): 2.4e-32, 59.88 38d in 177 aa, and to Yersinia pestis KIM hypothetical y3927 SWALL:AAM87471 (EMBL:AE013997) (177 aa) fasta scores: E(): 6.5e-25,57.89 38d in 152 aa | COG3166(7) | | | |
| 4640 |
|
| putative membrane protein | | | | |
| 4641 |
|
| outer membrane lipoprotein | COG3133(7) | | | |
| 4642 |
|
| putative ribonuclease|Barnase, a member of the family of homologous microbial ribonucleases, catalyses the cleavage of single-stranded RNA via a two-step mechanism thought to be similar to that of pancreatic ribonuclease; cd00933 | | | | |
| 4643 |
|
| putative exported protein | | | | |
| 4644 |
|
| putative lipoprotein | | | | |
| 4645 |
|
| putative tight adherance operon protein | | | | |
| 4646 |
|
| putative tight adherance operon protein,, | | | | |
| 4647 |
|
| putative tight adherance operon protein|Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking and secretion]; COG5010 | COG5010(7) | | | |
| 4648 |
|
| putative tight adherance operon protein|Flp pilus assembly protein TadC [Cell motility and secretion / Intracellular trafficking and secretion]; COG2064 | COG2064(7) | | | |
| 4649 |
|
| putative tight adherance operon protein|Flp pilus assembly protein TadB [Intracellular trafficking and secretion]; COG4965 | COG4965(7) | | | |
| 4650 |
|
| conserved hypothetical protein|Flp pilus assembly protein, ATPase CpaE [Intracellular trafficking and secretion]; COG4963 | COG4963(7) | | | |
| 4651 |
|
| putative tight adherance operon protein,, | | | | |
| 4652 |
|
| putative membrane transport protein|Sugar phosphate permease [Carbohydrate transport and metabolism]; COG2271|Major Facilitator Superfamily; pfam07690 | COG2271(7) | PF07690(7) | | |
| 4653 |
|
| putative iron transport protein|ABC-type enterochelin transport system, periplasmic component [Inorganic ion transport and metabolism]; COG4607|Siderophore binding protein FatB. These proteins have been shown to function as ABC-type initial receptors in the siderophore-mediated iron uptake in some eubacterial species; cd01140 | COG4607(7) | | | |
| 4654 |
|
| putative iron transport permease|ABC-type enterochelin transport system, permease component [Inorganic ion transport and metabolism]; COG4606 | COG4606(7) | | | |
| 4655 |
|
| putative iron transport permease|ABC-type enterochelin transport system, permease component [Inorganic ion transport and metabolism]; COG4605 | COG4605(7) | | | |
| 4656 |
|
| putative iron ABC transporter, ATP-binding protein|ABC transporters, involved in the uptake of siderophores, heme, and vitamin B12, are widely conserved in bacteria and archaea. Only very few species lack representatives of the siderophore family transporters. The E; cd03214|The pleiotropic drug resistance-like (PDR) family of ATP-binding cassette (ABC) transporters. PDR is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes; cd03232 | COG4604(6) | | | |
| 4657 |
|
| putative exported protein | | | | |
| 4658 |
|
| putative membrane protein|Outer membrane efflux protein. The OEP family (Outer membrane efflux protein) form trimeric channels that allow export of a variety of substrates in Gram negative bacteria. Each member of this family is composed of two repeats; pfam02321 | | PF02321(7) | | |
| 4659 |
|
| conserved hypothetical protein,, | | | | |
| 4660 |
|
| conserved hypothetical protein|Fic family protein [Function unknown]; COG3177|Fic protein family. This family consists of the Fic (filamentation induced by cAMP) protein and its relatives; pfam02661 | COG3177(7) | PF02661(7) | | |
| 4661 |
|
| general secretion pathway protein C | COG3031(6) | | | |
| 4662 |
|
| general secretion pathway protein K|Type II secretory pathway, component PulK [Intracellular trafficking and secretion]; COG3156 | COG3156(7) | | | |
| 4663 |
|
| conserved hypothetical protein|DsbA family, FrnE-like subfamily; composed of uncharacterized proteins containing a CXXC motif with similarity to DsbA and FrnE; cd03025 | | | | |
| 4664 |
|
| putative membrane protein | | | | |
| 4665 |
|
| conserved hypothetical protein|Tfp pilus assembly protein PilV [Cell motility and secretion / Intracellular trafficking and secretion]; COG4967 | COG4967(7) | | | |
| 4666 |
|
| putative cytochrome|Cytochrome c553 [Energy production and conversion]; COG2863 | COG2863(7) | | | |
| 4667 |
|
| putative membrane protein | | | | |
| 4668 |
|
| putative methyltransferase|Phospholipid N-methyltransferase [Lipid metabolism]; COG3963 | COG3963(7) | | | |
| 4669 |
|
| conserved hypothetical protein|ABC-type Fe3+-hydroxamate transport system, periplasmic component [Inorganic ion transport and metabolism]; COG0614|Periplasmic binding protein TroA_f. These proteins are predicted to function as initial receptors in the ABC metal ion uptake in eubacteria and archaea; cd01139 | COG0614(3) | PF01497(1) | | |
| 4670 |
|
| probable short-chain dehydrogenase|short chain dehydrogenase; PRK08177 | | | | |
| 4671 |
|
| hypothetical protein|No significant database matches to the full length CDS. C-terminal region is highly similar to Yersinia pestis hypothetical protein YPO2821 SWALL:Q8ZCY4 (EMBL:AJ414153) (115 aa) fasta scores: E(): 7.3e-41,97.39 38d in 115 aa | | | | |
| 4672 |
|
| putative LuxR-family regulatory proteins|DNA-binding response regulator in two-component regulatory system with NarX (or NarQ); PRK10651|helix_turn_helix, Lux Regulon; lux regulon (activates the bioluminescence operon; smart00421 | | | SM00421(7) | |
| 4673 |
|
| putative membrane protein | COG2510(7) | | | |
| 4674 |
|
| conserved hypothetical protein | | | | |
| 4675 |
|
| putative chemotactic transducer|FOG: PAS/PAC domain [Signal transduction mechanisms]; COG2202|PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels; cd00130|Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). Thought to undergo reversible methylation in response to attractants or repellants during bacterial chemotaxis; smart00283 | COG2202(7) | | SM00283(7) | |
| 4676 |
|
| conserved hypothetical protein|Sortase and related acyltransferases [Cell envelope biogenesis, outer membrane]; COG1247 | COG1247(7) | | | |
| 4677 |
|
| putative heme-binding protein|Arylsulfatase regulator (Fe-S oxidoreductase) [General function prediction only]; COG0641|Radical SAM superfamily; pfam04055 | COG0641(6) | PF04055(6) | | |
| 4678 |
|
| ABC transporter ATP-binding protein|ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; COG1136|This family is comprised of MJ0796 ATP-binding cassette, macrolide-specific ABC-type efflux carrier (MacAB), and proteins involved in cell division (FtsE), and release of liporoteins from the cytoplasmic membrane (LolCDE); cd03255 | COG1136(7) | | | |
| 4679 |
|
| putative exported protein|Membrane-fusion protein [Cell envelope biogenesis, outer membrane]; COG0845|multidrug efflux system subunit MdtA; PRK11556 | COG0845(7) | | | |
| 4680 |
|
| putative membrane protein, | | PF02687(1) | | |
| 4681 |
|
| putative luxR-family regulatory protein|helix_turn_helix, Lux Regulon; lux regulon (activates the bioluminescence operon; smart00421 | | | SM00421(7) | |
| 4682 |
|
| conserved hypothetical protein | COG5435(7) | | | |
| 4683 |
|
| putative membrane protein|OmpA family. The Pfam entry also includes MotB and related proteins which are not included in the Prosite family; pfam00691 | | PF00691(7) | | |
| 4684 |
|
| putative membrane protein | | | | |
| 4685 |
|
| putative fimbrial protein | | PF00419(6) | | |
| 4686 |
|
| frimbrial protein|Fimbrial protein; pfam00419 | COG3539(6) | PF00419(1) | | |
| 4687 |
|
| fimbrial protein|P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; COG3539 | COG3539(7) | | | |
| 4688 |
|
| putative exported protein|Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and vesicular transport]; COG3521 | COG3521(7) | | | |
| 4689 |
|
| conserved hypothetical protein | | | | |
| 4690 |
|
| putative glycosidase|endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; cd00056 | | | | |
| 4691 |
|
| putative AraC-family transcriptional regulatory protein|helix_turn_helix, arabinose operon control protein; smart00342|Bacterial regulatory helix-turn-helix proteins, AraC family; pfam00165 | | PF00165(7) | SM00342(7) | |
| 4692 |
|
| putative N-formylglutamate amidohydrolase|N-formylglutamate amidohydrolase [Amino acid transport and metabolism]; COG3741 | COG3741(7) | | | |
| 4693 |
|
| putative chlorohydrolase|Cytosine deaminase and related metal-dependent hydrolases [Nucleotide transport and metabolism / General function prediction only]; COG0402|Metallo-dependent hydrolases, subgroup D is part of the superfamily of metallo-dependent hydrolases, a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site; cd01313 | COG0402(7) | | | |
| 4694 |
|
| putative exported protein|Glycerophosphoryl diester phosphodiesterase [Energy production and conversion]; COG0584|Glycerophosphoryl diester phosphodiesterase family. E. coli has two sequence related isozymes of glycerophosphoryl diester phosphodiesterase (GDPD) - periplasmic and cytosolic; pfam03009 | COG0584(7) | PF03009(7) | | |
| 4695 |
|
| hypothetical phage protein | | | | |
| 4696 |
|
| putative exported protein | | | | |
| 4697 |
|
| conserved hypothetical protein | COG5654(7) | | | |
| 4698 |
|
| conserved hypothetical protein | COG5642(7) | | | |
| 4699 |
|
| putative acid shock protein | | | | |
| 4700 |
|
| conserved hypothetical protein | | | | |
| 4701 |
|
| putative exported protein|Uncharacterized protein conserved in bacteria [Function unknown]; COG4222 | COG4222(7) | | | |
| 4702 |
|
| conserved hypothetical protein|Uncharacterized small protein [Function unknown]; COG2879|Similar to Yersinia pestis hypothetical protein Ypo2233 SWALL:Q8ZEE0 (EMBL:AJ414151) (101 aa) fasta scores: E(): 4.2e-29, 70.9 38d in 110 aa and to Yersinia pestis KIM hypothetical Y2075 SWALL:AAM85639 (EMBL:AE013810) (109 aa) fasta scores: E(): 4.4e-29, 70 id in 110 aa | COG2879(6) | | | |
| 4703 |
|
| putative exported protein|Uncharacterized secreted protein [Function unknown]; COG5430|Also similar to YE1861 35.795 38dentity in 176 aa overlap and YE1859 34.831 38dentity in 178 aa overlap | COG5430(7) | | | |
| 4704 |
|
| conserved hypothetical protein | | | | |
| 4705 |
|
| putative membrane protein | | | | |
| 4706 |
|
| attachment invasion locus protein|outer membrane protein X; PRK09408 | | | | Q56957(1) |
| 4707 |
|
| conserved hypothetical protein | | | | |
| 4708 |
|
| conserved hypothetical protein | | | | |
| 4709 |
|
| conserved hypothetical protein | | | | |
| 4710 |
|
| putative ABC transporter (ATP-binding protein)|ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; COG1132|ABC transporter transmembrane region. This family represents a unit of six transmembrane helices. Many members of the ABC transporter family (pfam00005) have two such regions; pfam00664|MsbA is an essential ABC transporter, closely related to eukaryotic MDR proteins; cd03251 | COG1132(7) | PF00664(7) | | |
| 4711 |
|
| conserved hypothetical protein | | | | |
| 4712 |
|
| putative lipoprotein | | | | |
| 4713 |
|
| putative LuxR-family regulatory protein|Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; COG2197|Sigma-70, region 4. Region 4 of sigma-70 like sigma-factors are involved in binding to the -35 promoter element via a helix-turn-helix motif. Due to the way Pfam works, the threshold has been set artificially high to prevent overlaps with other helix...; cl01055 | COG2197(6) | | SM00421(1) | |
| 4714 |
|
| N-acylhomoserine lactone synthase|Autoinducer synthetase; pfam00765 | | PF00765(7) | | |
| 4715 |
|
| quorum-sensing transcriptional activator|Autoinducer binding domain. This domain is found a a large family of transcriptional regulators. This domain specifically binds to autoinducer molecules; pfam03472|Sigma-70, region 4. Region 4 of sigma-70 like sigma-factors are involved in binding to the -35 promoter element via a helix-turn-helix motif. Due to the way Pfam works, the threshold has been set artificially high to prevent overlaps with other helix...; cl01055 | | PF03472(7) | | |
| 4716 |
|
| cold shock-like protein cspE3|Cold shock proteins [Transcription]; COG1278 | COG1278(7) | | | |
| 4717 |
|
| pH 6 antigen precursor (antigen 4) (adhesin) | | | | Q56982(1) |
| 4718 |
|
| putative membrane protein | | | | Q56981(1) |
| 4719 |
|
| putative regulatory protein|DNA-binding winged-HTH domains [Transcription]; COG3710 | COG3710(1) | | | P68589(1) |
| 4720 |
|
| putative Mut family protein|Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X; cd04678 | | | | |
| 4721 |
|
| conserved hypothetical protein | | | | |
| 4722 |
|
| conserved hypothetical protein | | | | |
| 4723 |
|
| putative exported protein|Esterase/lipase [Lipid metabolism]; COG0657|Esterases and lipases (includes fungal lipases, cholinesterases, etc.) These enzymes act on carboxylic esters (EC: 3.1.1.-). The catalytic apparatus involves three residues (catalytic triad): a serine, a glutamate or aspartate and a histidine; cd00312 | COG0657(7) | | | |
| 4724 |
|
| putative regulatory protein|Helix-turn-helix (HTH) MerR-like transcription regulator, N-terminal domain; cd00592|Helix-turn-helix (HTH) transcription regulator MerR2 and related proteins. MerR2 in Bacillus cereus RC607 regulates resistance to organomercurials; cd04769 | | | | |
| 4725 |
|
| iron(III)-binding periplasmic protein|Bacterial extracellular solute-binding protein. This family also includes the bacterial extracellular solute-binding protein family POTD/POTF; pfam01547|ABC-type Fe3+ transport system, periplasmic component [Inorganic ion transport and metabolism]; COG1840 | COG1840(6) | PF01547(1) | | |
| 4726 |
|
| iron(III)-transport system permease|ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism]; COG1178 | COG1178(5)|COG1177(5), COG1178(1)|COG1176(1)|COG0555(1), COG1178(1)|COG1177(1)|COG0555(1) | | | |
| 4727 |
|
| iron(III)-transport ATP-binding protein|ABC-type spermidine/putrescine transport systems, ATPase components [Amino acid transport and metabolism]; COG3842|ABC Carbohydrate and Solute Transporters-like subgroup. This family is comprised of proteins involved in the transport of apparently unrelated solutes and proteins specific for di- and oligosaccharides and polyols; cd03259 | COG3842(1) | | | Q668Q3(1) |
| 4728 |
|
| putative membrane protein | COG4331(6) | | | |
| 4729 |
|
| putative lipoprotein|Uncharacterized protein conserved in bacteria [Function unknown]; COG4380 | COG4380(7) | | | |
| 4730 |
|
| putative lipoprotein|Uncharacterized protein conserved in bacteria [Function unknown]; COG4259 | COG4259(7) | | | |
| 4731 |
|
| putative lipoprotein|Uncharacterized protein involved in formation of curli polymers [Cell envelope biogenesis, outer membrane]; COG1462 | COG1462(7) | | | |
| 4732 |
|
| conserved hypothetical protein|Uncharacterized protein conserved in bacteria [Function unknown]; COG3575 | COG3575(7) | | | |
| 4733 |
|
| putative two-component system response regulator|Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; COG0745|Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; contains; cd00156 | COG0745(7) | | | |
| 4734 |
|
| conserved hypothetical protein|Uncharacterized protein conserved in bacteria [Function unknown]; COG4519 | COG4519(7) | | | |
| 4735 |
|
| conserved hypothetical protein|Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi, pl; cd00189 | | | | |
| 4736 |
|
| putative carboxypeptidase|D-alanyl-D-alanine carboxypeptidase [Cell envelope biogenesis, outer membrane]; COG1876 | COG1876(7) | | | |
| 4737 |
|
| putative exported protein|Inhibitor of vertebrate lysozyme (Ivy). This bacterial family is a strong inhibitor of vertebrate lysozyme; pfam08816 | | PF08816(7) | | |
| 4738 |
|
| putative membrane protein|Predicted permeases [General function prediction only]; COG0679 | COG0679(7) | | | |
| 4739 |
|
| putative exported protein|Similar in part to Yersinia pestis hypothetical protein Ypo2919 SWALL:Q8ZCQ3 (EMBL:AJ414154) (192 aa) fasta scores: E(): 6.9e-10, 30.66 38d in 150 aa | | | | |
| 4740 |
|
| putative phospholipase A accessory protein|ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example); cd00204 | | | | |
| 4741 |
|
| phospholipase A|Previously sequenced as: Yersinia enterocolitica phospholipase A YplA SWALL:O85477 (EMBL:AF067849) (324 aa) fasta scores: E(): 9.3e-114, 100 38d in 324 aa. Also highly similar to Yersinia pestis phospholipase A YplA or Ypo2706 SWALL:Q8ZD83 (EMBL:AJ414153) (320 aa) fasta scores: E(): 9.1e-75, 69.01 38d in 326 aa | | | | |
| 4742 |
|
| putative membrane protein|Integral membrane protein possibly involved in chromosome condensation [Cell division and chromosome partitioning]; COG0239 | COG0239(7) | | | Q667R0(1) |
| 4743 |
|
| putative membrane protein|camphor resistance protein CrcB; PRK01636 | | | | Q667Q9(1) |
| 4744 |
|
| urease accessory protein|Urease accessory protein UreF [Posttranslational modification, protein turnover, chaperones]; COG0830 | COG0830(7) | | | P52318(1) |
| 4745 |
|
| urease accessory protein|Urease accessory protein UreE [Posttranslational modification, protein turnover, chaperones]; COG2371|UreE urease accessory protein. UreE is a metallochaperone assisting the insertion of a Ni2+ ion in the active site of urease, an important step in the in vivo assembly of urease, an enzyme that hydrolyses urea into ammonia and carbamic acid; cd00571 | COG2371(7) | | | P52317(1) |
| 4746 |
|
| putative membrane protein|putative MFS family transporter protein; PRK03633|Major Facilitator Superfamily; pfam07690 | | PF07690(1) | | |
| 4747 |
|
| conserved hypothetical protein|Predicted nuclease of the RNAse H fold, HicB family [General function prediction only]; COG1598|nickel responsive regulator; PRK00630 | COG1598(7) | PF0150(1) | | |
| 4748 |
|
| conserved hypothetical protein|Uncharacterized protein conserved in bacteria [Function unknown]; COG4701 | COG4701(7) | | | |
| 4749 |
|
| putative membrane protein|Weakly similar to Yersinia pestis hypothetical protein Ypo2963 SWALL:Q8ZCL9 (EMBL:AJ414154) (282 aa) fasta scores: E(): 3.7e-12, 27.02 38d in 259 aa | | | | |
| 4750 |
|
| putative pectinesterase|Pectin methylesterase [Carbohydrate transport and metabolism]; COG4677 | COG4677(7) | | | |
| 4751 |
|
| conserved hypothetical protein,, | | | | |
| 4752 |
|
| sugar transport system, permease protein | COG0395(7) | | | |
| 4753 |
|
| sugar transport system, permease protein | COG1175(7) | | | |
| 4754 |
|
| putative sugar binding protein|ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; COG1653|Bacterial extracellular solute-binding protein. This family also includes the bacterial extracellular solute-binding protein family POTD/POTF; pfam01547 | COG1653(7) | PF01547(7) | | |
| 4755 |
|
| putative exported protein|Hydroxymethylbilane synthase (HMBS), also known as porphobilinogen deaminase (PBGD), is an intermediate enzyme in the biosynthetic pathway of tetrapyrrolic ring systems, such as heme, chlorophylls, and vitamin B12; cd00494 | | | | |
| 4756 |
|
| conserved hypothetical protein|Heparinase II/III-like protein. This family features sequences that are similar to a region of the Flavobacterium heparinum proteins heparinase II and heparinase III; pfam07940 | | PF07940(7) | | |
| 4757 |
|
| putative exported protein | | | | |
| 4758 |
|
| putative membrane protein|Predicted permeases [General function prediction only]; COG0679 | COG0679(7) | | | |
| 4759 |
|
| putative exported protein,, | | | | |
| 4760 |
|
| putative exported protein|Fimbrial Usher protein. This protein is involved in biogenesis of gram negative bacterial pili; pfam00577 | COG3188(6) | PF00577(1) | | |
| 4761 |
|
| putative exported protein | COG3121(6) | | | |
| 4762 |
|
| putative exported protein|P pilus assembly protein, chaperone PapD [Cell motility and secretion / Intracellular trafficking and secretion]; COG3121 | COG3121(1) | | | |
| 4763 |
|
| putative exported protein | | | | |
| 4764 |
|
| conserved hypothetical protein|TIM-barrel signal transduction protein. This domain is likely to have a TIM barrel fold related to IGPS; pfam09370 | | PF09370(7) | | |
| 4765 |
|
| conserved hypothetical protein|Uncharacterised protein family (UPF0261); pfam06792 | | PF06792(7) | | |
| 4766 |
|
| putative TetR-family regulatory protein|Transcriptional regulator [Transcription]; COG1309 | COG1309(1) | | | |
| 4767 |
|
| putative peroxiredoxin/glutaredoxin family protein|Peroxiredoxin (PRX) family, PRX5-like subfamily; members are similar to the human protein, PRX5, a homodimeric TRX peroxidase, widely expressed in tissues and found cellularly in mitochondria, peroxisomes and the cytosol; cd03013|Glutaredoxin (GRX) family, PRX5 hybrid subfamily; composed of hybrid proteins containing peroxiredoxin (PRX) and GRX domains, which is found in some pathogenic bacteria and cyanobacteria; cd03029 | | | | |
| 4768 |
|
| putative pyridine nucleotide-disulphide oxidoreductase|dihydrolipoamide dehydrogenase; PRK06292|Pyridine nucleotide-disulphide oxidoreductase. This family includes both class I and class II oxidoreductases and also NADH oxidases and peroxidases. This domain is actually a small NADH binding domain within a larger FAD binding domain; pfam00070 | | PF00070(7)|PF02852(7) | | |
| 4769 |
|
| HlyD family secretion protein|predicted membrane fusion protein of efflux pump; PRK10476 | | PF00529(7) | | |
| 4770 |
|
| ABC transporter protein|ABC-type protease/lipase transport system, ATPase and permease components [General function prediction only]; COG4618|ABC transporter transmembrane region. This family represents a unit of six transmembrane helices. Many members of the ABC transporter family (pfam00005) have two such regions; pfam00664 | COG4618(7) | PF00664(1) | | |
| 4771 |
|
| hemophore HasA|Heme-binding protein A (HasA). Free iron is limited in vertebrate hosts, thus an alternative to siderophores has been developed by pathogenic bacteria to access host iron bound in protein complexes; pfam06438 | | PF06438(6) | | |
| 4774 |
|
| putative periplasmic protein,,, | | | | |
| 4775 |
|
| putative exported protein|Lyase, N terminal. Members of this family are predominantly found in chondroitin ABC lyase I, and adopt a jelly-roll fold topology consisting of a two-layered bent beta-sheet sandwich with one short alpha-helix; pfam09092|Glycosaminoglycan (GAG) polysaccharide lyase family; cd01083|highly similar to Yersinia pestis CO92 YPO0824 and Yersinia pestis KIM y3211. Contains Polysaccharide lyase family 8, N-terminal (Interpro|IPR003159, Cellular Component: extracellular (GO:0005576), (GO:0016829)) | | PF09092(6) | | |
| 4776 |
|
| putative exported protein|Autotransporter beta-domain. Secretion of protein products occurs by a number of different pathways in bacteria. One of these pathways known as the type V pathway was first described for the IgA1 protease; pfam03797|highly similar to Yersinia pestis CO92 YPO0823 and Yersinia pestis KIM y3210. Contains Autotransporter beta-domain (Interpro|IPR005546). Contains Outer membrane autotransporter barrel (Interpro|IPR006315) | | PF03797(6) | | |
| 4777 |
|
| putative exported protein|highly similar to Yersinia pestis CO92 YPO0822 and Yersinia pestis KIM y3209, | | | | |
| 4779 |
|
| putative LacI-family transcriptional regulatory protein|helix_turn _helix lactose operon repressor; smart00354|Transcriptional regulators [Transcription]; COG1609 | COG1609(5) | | SM00354(4) | |
| 4780 |
|
| hypothetical protein|Uncharacterized protein conserved in bacteria [Function unknown]; COG4289|highly similar to Yersinia pestis CO92 YPO0843 and Yersinia pestis KIM y3228 | COG4289(6) | | | |
| 4781 |
|
| conserved hypothetical protein|Predicted unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins [General function prediction only]; COG4225|highly similar to Yersinia pestis CO92 YPO0840 and Yersinia pestis KIM y3225 | COG4225(6) | | | |
| 4782 |
|
| putative sulfatase|Arylsulfatase A and related enzymes [Inorganic ion transport and metabolism]; COG3119|Sulfatase; pfam00884|highly similar to Yersinia pestis CO92 YPO0829 and Yersinia pestis KIM y3215. Contains Sulfatase (Interpro|IPR000917, (GO:0008152), (GO:0008484)). Contains Twin-arginine translocation pathway signal (Interpro|IPR006311) | COG3119(6) | PF00884(6) | | |
| 4783 |
|
| probable N-acetylmuramoyl-L-alanine amidase|N-acetyl-anhydromuranmyl-L-alanine amidase; PRK11789|Putative peptidoglycan binding domain. This domain is composed of three alpha helices. This domain is found at the N or C terminus of a variety of enzymes involved in bacterial cell wall degradation; pfam01471|highly similar to Yersinia pestis CO92 YPO1683 and Yersinia pestis KIM y1845. Contains N-acetylmuramoyl-L-alanine amidase, family 2 (Interpro|IPR002502, (GO:0009253)) | | PF01471(6) | | |
| 4784 |
|
| insecticidal toxin complex|Salmonella virulence plasmid 65kDa B protein; pfam03534 | | PF03534(6) | | |
| 4785 |
|
| putative acyltransferase|1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid metabolism]; COG0204|highly similar to Yersinia pestis CO92 YPO2815 and Yersinia pestis KIM y1117. Contains Phospholipid/glycerol acyltransferase (Interpro|IPR002123, (GO:0008152), (GO:0008415)) | COG0204(6) | | | |
| 4786 |
|
| conserved hypothetical protein|Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and vesicular transport]; COG3516|highly similar to Yersinia pestis CO92 YPO0500 and Yersinia pestis KIM y3675 | COG3516(6) | | | |
| 4788 |
|
| enhancing factor (viral)|Viral enhancin protein; pfam03272|highly similar to Yersinia pestis CO92 YPO0339 and Yersinia pestis KIM y0597. Contains Viral enhancin protein (Interpro|IPR004954). Contains Neutral zinc metallopeptidases, zinc-binding region (Interpro|IPR006025, (GO:0008237), (GO:0008270)) | | PF03272(6) | | |
| 4789 |
|
| putative adhesin|haemagglutination activity domain. This domain is suggested to be a carbohydrate- dependent haemagglutination activity site. It is found in a range of haemagglutinins and haemolysins; pfam05860, | | PF05860(4) | | |
| 4799 |
|
| putative ABC transporter permease protein|ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism]; COG1177 | COG1177(7) | | | |
| 4800 |
|
| spermidine/putrescine ABC transporter membrane component|Binding-protein-dependent transport system inner membrane component. The alignments cover the most conserved region of the proteins, which is thought to be located in a cytoplasmic loop between two transmembrane domains. The members of this family have...; cl00427 | COG1176(6) | | | |
| 4801 |
|
| putative transcriptional regulator (LysR familiy)|Bacterial regulatory helix-turn-helix protein, lysR family; pfam00126|Transcriptional regulator [Transcription]; COG0583|LysR substrate binding domain. The structure of this domain is known and is similar to the periplasmic binding proteins; pfam03466 | COG0583(7) | PF00126(7)|PF03466(7) | | |
| 4802 |
|
| hypothetical protein|Uncharacterized proteins, LmbE homologs [Function unknown]; COG2120 | COG2120(7) | | | |
| 4803 |
|
| hypothetical protein|Protein of unknown function, DUF583. This family contains several uncharacterised hypothetical proteins; pfam04519 | COG1664(6) | PF04519(1) | | |
| 4805 |
|
| molybdate transport protein (ABC superfamily, peri_bind)|ABC-type molybdate transport system, periplasmic component [Inorganic ion transport and metabolism]; COG0725 | COG0725(7) | | | |
| 4807 |
|
| putative ABC transporter periplasmic binding protein|ABC-type Fe3+ transport system, periplasmic component [Inorganic ion transport and metabolism]; COG1840 | COG1840(7) | PF01547(6) | | |
| 4808 |
|
| putative ABC transporter|ABC-type spermidine/putrescine transport systems, ATPase components [Amino acid transport and metabolism]; COG3842|PotA is an ABC-type transporter and the ATPase component of the spermidine/putrescine-preferential uptake system consisting of PotA, -B, -C, and -D; cd03300 | COG3842(7) | | | |
| 4809 |
|
| hypothetical transcriptional regulator|Transcriptional regulators [Transcription]; COG2186|Bacterial regulatory proteins, gntR family. This family of regulatory proteins consists of the N-terminal HTH region of GntR-like bacterial transcription factors. At the C-terminus there is usually an effector-binding/oligomerisation domain. The GntR...; cl02580 | COG2186(1), COG1802(6) | PF07729(6) | | |
| 4810 |
|
| hypothetical protein | | | | |
| 4811 |
|
| hypothetical protein | | | | |
| 4812 |
|
| cysteine transport protein (ABC superfamily, peri_bind)|Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of substrates, such as, amino acids, peptides, sugars, vitamins and inorganic i; cd00134 | | | | |
| 4813 |
|
| glutamine ABC transporter permease component|ABC-type amino acid transport system, permease component [Amino acid transport and metabolism]; COG0765 | COG0765(7) | | | |
| 4814 |
|
| putative amino acid transport protein (ABC superfamily, membrane) | COG0765(7) | | | |
| 4815 |
|
| putative 4-carboxymuconolactone decarboxylase|Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit [Function unknown]; COG0599 | COG0599(7) | | | |
| 4817 |
|
| putative endoribonuclease|YjgH belong to a large family of proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase however there is no sequence similarity and no functional connection; cd02198 | | | | |
| 4818 |
|
| hypothetical protein | | | | |
| 4819 |
|
| hypothetical protein | | | | |
| 4820 |
|
| hypothetical protein | COG4104(6) | | | |
| 4821 |
|
| hypothetical protein,, | | | | |
| 4822 |
|
| putative transcriptional regulator, sorC family|Transcriptional regulator, contains sigma factor-related N-terminal domain [Transcription]; COG2390|Sigma-70, region 4. Region 4 of sigma-70 like sigma-factors are involved in binding to the -35 promoter element via a helix-turn-helix motif; pfam04545|Putative sugar-binding domain. This probable domain is found in bacterial transcriptional regulators such as DeoR and SorC. These proteins have an amino-terminal helix-turn-helix pfam00325 that binds to DNA; pfam04198 | COG2390(7) | PF04545(1)|PF04198(1), PF04198(6) | | |
| 4823 |
|
| maltoporin precursor|The Maltoporin-like channels (LamB porin) form a trimeric structure which facilitate the diffusion of maltodextrins and other sugars across the outer membrane of Gram-negative bacteria; cd01346 | | | | Q666Z8(1) |
| 4824 |
|
| putative galactosidase|Arabinogalactan endo-1,4-beta-galactosidase [Carbohydrate transport and metabolism]; COG3867 | COG3867(7) | | | |
| 4825 |
|
| putative binding-protein-dependent transport systems inner membrane component|ABC-type maltose transport systems, permease component [Carbohydrate transport and metabolism]; COG3833 | COG3833(7) | | | |
| 4828 |
|
| hypothetical protein|Uncharacterized protein conserved in bacteria [Function unknown]; COG2991 | COG2991(7) | | | |
| 4829 |
|
| putative aminotransferase|Aspartate/tyrosine/aromatic aminotransferase [Amino acid transport and metabolism]; COG0436 | COG0436(6) | | | |
| 4830 |
|
| putative mannosyltransferase|Glycosyl transferases group 1. Mutations in this domain of phosphatidylinositol N-acetylglucosaminyltransferase subunit A lead to disease (Paroxysmal Nocturnal haemoglobinuria); pfam00534|highly similar to Yersinia pestis CO92 wbyK and Yersinia pestis KIM y1078. Contains Glycosyl transferase, family 1 (Interpro|IPR001296, (GO:0009058)) | | PF00534(6) | | |
| 4831 |
|
| putative secretion protein HlyD|multidrug efflux system subunit MdtA; PRK11556 | | PF00529(8) | | |
| 4835 |
|
| Hypothetical protein|Residues 13 to 409 of 537 are 50.72 pct identical to residues 1970 to 2381 of 2535 from GenPept.129 : >emb|CAC91295.1| (AJ414152) putative hemolysin [Yersinia pestis], | | | | |
| 4839 |
|
| putative tellurium resistance protein|VWA subfamily: Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF); cd01464|highly similar to Yersinia pestis CO92 terY and Yersinia pestis KIM y3581. Contains Von Willebrand factor, type A (Interpro|IPR002035) | | | | |
| 4840 |
|
| putative tellurium resistance protein|Uncharacterized proteins involved in stress response, homologs of TerZ and putative cAMP-binding protein CABP1 [Signal transduction mechanisms]; COG2310|highly similar to Yersinia pestis CO92 terX and Yersinia pestis KIM y3583. Contains Bacterial stress protein (Interpro|IPR003325, (GO:0006950)) | COG2310(6) | | | |
| 4841 |
|
| conserved hypothetical protein|VWA subfamily: Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF); cd01464|highly similar to Yersinia pestis CO92 YPO0595 and Yersinia pestis KIM y3584. Contains Von Willebrand factor, type A (Interpro|IPR002035) | | | | |
| 4842 |
|
| hypothetical protein|highly similar to Yersinia pestis CO92 YPO0593 and Yersinia pestis KIM y3586 | | | | |
| 4844 |
|
| conserved hypothetical protein|Uncharacterized protein conserved in bacteria [Function unknown]; COG3501|Protein of unknown function, DUF586. This family contains a conserved region in several bacterial proteins of unknown function; pfam04524|highly similar to Yersinia pestis CO92 YPO0507 and Yersinia pestis KIM y3668. Contains Pollen allergen Poa pIX/Phl pVI, C-terminal (Interpro|IPR001778). Contains Rhs element Vgr protein (Interpro|IPR006533) | COG3501(6) | PF04524(6) | | |
| 4868 |
|
| Member of the Rhodanese Homology Domain superfamily. This CD includes the putative rhodanese-like protein, Psp2, of Yersinia pestis biovar Medievalis and other similar uncharacterized proteins; cd01521|No significant matches | | | | |
| 4869 |
|
| unknown protein encoded by prophage CP-933O|No significant matches, | | | | |
| 4870 |
|
| putative chaperone|P pilus assembly protein, chaperone PapD [Cell motility and secretion / Intracellular trafficking and secretion]; COG3121|Gram-negative pili assembly chaperone, N-terminal domain. C2 domain-like beta-sandwich fold; pfam00345|Residues 4 to 224 of 229 are 44.68 pct identical to residues 3 to 237 of 246 from GenPept 118 : gi|3818597|gb|AAC69580.1| (AF091251) unknown [Yersinia pestis] | COG3121(7) | PF00345(2)|PF02753(2), PF00345(6) | | |
| 4934 |
|
| putative chaperone protein|P pilus assembly protein, chaperone PapD [Cell motility and secretion / Intracellular trafficking and secretion]; COG3121|Gram-negative pili assembly chaperone, N-terminal domain. C2 domain-like beta-sandwich fold; pfam00345|highly similar to Yersinia pestis CO92 YPO1711 and Yersinia pestis KIM y1873. Contains Flavin-containing monooxygenase FMO (Interpro|IPR000960, (GO:0006118)). Contains Bacterial pili assembly chaperone (Interpro|IPR001829, (GO:0030288)) | COG3121(6) | PF00345(6)|PF02753(6) | | |
| 4938 |
|
| putative sugar-binding periplasmic protein|ABC-type xylose transport system, periplasmic component [Carbohydrate transport and metabolism]; COG4213|highly similar to Yersinia pestis CO92 YPO2581. Contains Periplasmic binding protein/LacI transcriptional regulator (Interpro|IPR001761) | COG4213(6)|COG1879(6) | | | |
| 4939 |
|
| sugar transport system permease protein|Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components [Carbohydrate transport and metabolism]; COG1172|highly similar to Yersinia pestis CO92 YPO2583 and Yersinia pestis KIM. Contains Bacterial inner-membrane translocator (Interpro|IPR001851, (GO:0016020)) | COG1172(6) | | | |
| 4952 |
|
| putative LysR-family transcriptional regulator|Transcriptional regulator [Transcription]; COG0583|Bacterial regulatory helix-turn-helix protein, lysR family; pfam00126|LysR substrate binding domain. The structure of this domain is known and is similar to the periplasmic binding proteins; pfam03466 | COG0583(6) | PF00126(6)|PF03466(6) | | |
| 4962 |
|
| hypothetical protein|highly similar to Yersinia pestis KIM y3443,, | | | | |
| 4963 |
|
| putative regulatory protein|Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment; cd00383|highly similar to Yersinia pestis CO92 YPO0736 and Yersinia pestis KIM y3442. Contains Transcriptional regulatory protein, C terminal (Interpro|IPR001867, (GO:0006355)) | | | | |
| 4972 |
|
| putative membrane receptor protein|TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; cd01347|Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; COG1629 | COG1629(6) | | | |
| 4975 |
|
| putative membrane protein|High-affinity Fe2+/Pb2+ permease [Inorganic ion transport and metabolism]; COG0672 | COG0672(6) | | | |
| 4976 |
|
| putative membrane protein|ABC-type transport system, involved in lipoprotein release, permease component [Cell envelope biogenesis, outer membrane]; COG4591|Predicted permease. This is a family of predicted permeases and hypothetical transmembrane proteins; pfam02687 | COG4591(6) | PF02687(6) | | |
| 4994 |
|
| | | | | |
| 4996 |
|
| anthranilate synthase component II|Type 1 glutamine amidotransferase (GATase1) domain found in Anthranilate synthase (ASase). This group contains proteins similar to para-aminobenzoate (PABA) synthase and ASase; cd01743 | | | | |
| 4997 |
|
| hypothetical protein|highly similar to Yersinia pestis CO92 YPO0100 and Yersinia pestis KIM y0288.,,, | | | | |
| 4998 |
|
| putative exported protein|highly similar to Yersinia pestis CO92 YPO0102., | | | | |
| 4999 |
|
| putative exported protein|Glutamine cyclotransferase [Posttranslational modification, protein turnover, chaperones]; COG3823|highly similar to Yersinia pestis CO92 YPO3874 and Yersinia pestis KIM y0354 | COG3823(6) | | | |
| 5000 |
|
| hypothetical protein|highly similar to Yersinia pestis CO92 YPO3803 and Yersinia pestis KIM y0427,,, | | | | |
| 5001 |
|
| putative type III secretion apparatus|highly similar to Yersinia pestis CO92 YPO0259 and Yersinia pestis KIM y0516 | | | | |
| 5002 |
|
| putative type III secretion apparatus|Bacterial type III secretion system protein (yscI_hrpB_dom). This entry consists of bacterial type III secretion system proteins which share a conserved C-terminal domain; pfam09525|highly similar to Yersinia pestis CO92 YPO0262 | | PF09525(6) | | |
| 5003 |
|
| hypothetical protein|highly similar to Yersinia pestis KIM y0523, | | | | |
| 5004 |
|
| putative type III secretion system component|highly similar to Yersinia pestis KIM y0524 | | | | |
| 5005 |
|
| type III secretion system apparatus protein|ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only]; COG0488|highly similar to Yersinia pestis CO92 YPO0268 and Yersinia pestis KIM y0527. | COG0488(6) | | | |
| 5006 |
|
| hypothetical protein|highly similar to Yersinia pestis KIM y0528, | | | | |
| 5007 |
|
| putative methylenetetrahydrofolate reductase|Methylenetetrahydrofolate reductase (MTHFR). 5,10-Methylenetetrahydrofolate is reduced to 5-methyltetrahydrofolate by methylenetetrahydrofolate reductase, a cytoplasmic, NAD(P)-dependent enzyme; cd00537|highly similar to Yersinia pestis CO92 YPO0287 and Yersinia pestis KIM y0548. Contains Methylenetetrahydrofolate reductase (Interpro|IPR003171, (GO:0006555)) | | | | |
| 5008 |
|
| putative exported protein|highly similar to Yersinia pestis CO92 YPO0301 and Yersinia pestis KIM y0561, | | | | |
| 5009 |
|
| hypothetical protein|highly similar to Yersinia pestis CO92 YPO0306 and Yersinia pestis KIM y0565. Contains Cytochrome c heme-binding site (Interpro|IPR000345, (GO:0006118)). Contains Zn-finger, C2H2 type (Interpro|IPR007087),,, | | | | |
| 5010 |
|
| putative oxidoreductase|FAD/FMN-containing dehydrogenases [Energy production and conversion]; COG0277|FAD binding domain. This family consists of various enzymes that use FAD as a co-factor, most of the enzymes are similar to oxygen oxidoreductase; pfam01565|Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands; cd00063 | COG0277(6) | PF01565(5)|PF08031(5), PF08031(1) | | |
| 5011 |
|
| putative transcriptional regulatory protein|Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; cd00093|highly similar to Yersinia pestis CO92 YPO3485 and Yersinia pestis KIM y0699. Contains Helix-turn-helix motif, Cro repressor (Interpro|IPR000655, (GO:0006355)). Contains Helix-turn-helix motif (Interpro|IPR001387, (GO:0003677)) | | | | |
| 5012 |
|
| M48 peptidase family protein|Peptidase family M48; pfam01435|highly similar to Yersinia pestis CO92 YPO0398 and Yersinia pestis KIM y3784. Contains Peptidase family M48 (Interpro|IPR001915, (GO:0016020)), | | PF01435(6) | | |
| 5013 |
|
| putative exported protein|highly similar to Yersinia pestis CO92 YPO0419 and Yersinia pestis KIM y3761., | | | | |
| 5014 |
|
| putative exported protein|highly similar to Yersinia pestis CO92 YPO0489 and Yersinia pestis KIM y3686, | | | | |
| 5015 |
|
| hypothetical protein|Uncharacterized conserved protein [Function unknown]; COG5419|highly similar to Yersinia pestis CO92 YPO0498 and Yersinia pestis KIM y3677 | COG5419(6) | | | |
| 5016 |
|
| hypothetical protein|Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and vesicular transport]; COG3515|highly similar to Yersinia pestis CO92 YPO0499 and Yersinia pestis KIM y3676. | COG3515(6) | | | |
| 5017 |
|
| conserved hypothetical protein|Type VI protein secretion system component Hcp (secreted cytotoxin) [Intracellular trafficking, secretion, and vesicular transport]; COG3157|highly similar to Yersinia pestis CO92 YPO0502 and Yersinia pestis KIM y3673 | COG3157(6) | | | |
| 5018 |
|
| conserved hypothetical protein|Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and vesicular transport]; COG3518|highly similar to Yersinia pestis CO92 YPO0503 and Yersinia pestis KIM y3672 | COG3518(6) | | | |
| 5019 |
|
| conserved hypothetical protein|Type VI protein secretion system component VasA [Intracellular trafficking, secretion, and vesicular transport]; COG3519|highly similar to Yersinia pestis CO92 YPO0504 and Yersinia pestis KIM y3671 | COG3519(6) | | | |
| 5020 |
|
| conserved hypothetical protein|Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and vesicular transport]; COG3520|highly similar to Yersinia pestis CO92 YPO0505 and Yersinia pestis KIM y3670. | COG3520(6) | | | |
| 5021 |
|
| Uncharacterized low-complexity proteins|Uncharacterized protein conserved in bacteria [Function unknown]; COG5351|highly similar to Yersinia pestis KIM y3665. Contains Pentapeptide repeat (Interpro|IPR001646), | COG1357(2), COG5351(4)|COG1357(4) | | | |
| 5022 |
|
| hypothetical protein|highly similar to Yersinia pestis CO92 YPO0511 and Yersinia pestis KIM y3663,,, | | | | |
| 5023 |
|
| putative lipoprotein|Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and vesicular transport]; COG3521|highly similar to Yersinia pestis CO92 YPO0512 | COG3521(6) | | | |
| 5024 |
|
| conserved hypothetical protein|Type VI protein secretion system component VasF [Intracellular trafficking, secretion, and vesicular transport]; COG3455|OmpA family. The Pfam entry also includes MotB and related proteins which are not included in the Prosite family; pfam00691|highly similar to Yersinia pestis KIM y3659. Contains OmpA/MotB domain (Interpro|IPR006665) | COG3455(6) | PF00691(6) | | |
| 5025 |
|
| hypothetical protein|highly similar to Yersinia pestis KIM y3657,,, | | | | |
| 5026 |
|
| putative dehydrogenase|short chain dehydrogenase; PRK06841|3-ketoacyl-(acyl-carrier-protein) reductase; PRK05557|highly similar to Yersinia pestis CO92 YPO3351 and Yersinia pestis KIM y0839. Contains Short-chain dehydrogenase/reductase SDR (Interpro|IPR002198, (GO:0008152), (GO:0016491)). Contains Glucose/ribitol dehydrogenase (Interpro|IPR002347, (GO:0008152), (GO:0016491)) | | | | |
| 5027 |
|
| hypothetical protein|highly similar to Yersinia pestis CO92 YPO3344 and Yersinia pestis KIM y0846., | | | | |
| 5028 |
|
| hypothetical protein|ShET2 enterotoxin, N-terminal region. The members of this family are are sequences that are similar to the N-terminal half of the ShET2 enterotoxin produced by Shigella flexneri and Escherichia coli; pfam07906 | | PF07906(6) | | |
| 5029 |
|
| putative sugar ABC transporter, permease protein|Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components [Carbohydrate transport and metabolism]; COG1172|highly similar to Yersinia pestis CO92 YPO3331 and Yersinia pestis KIM y0858. Contains Bacterial inner-membrane translocator (Interpro|IPR001851, (GO:0016020)). Contains Sodium:dicarboxylate symporter (Interpro|IPR001991, (GO:0016020)) | COG1172(6) | | | |
| 5030 |
|
| putative sugar ABC transporter, periplasmic protein|ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; COG1879|D-xylose transporter subunit XylF; PRK10355|highly similar to Yersinia pestis CO92 YPO3328 and Yersinia pestis KIM y0861. Contains Periplasmic binding protein/LacI transcriptional regulator (Interpro|IPR001761) | COG1879(6) | | | |
| 5031 |
|
| putative cytochrome B562|Soluble cytochrome b562 [Energy production and conversion]; COG3783|highly similar to Yersinia pestis CO92 cybC | COG3783(6) | | | |
| 5032 |
|
| hypothetical protein|Adhesin biosynthesis transcription regulatory protein. This family includes PapB, DaaA, FanA, FanB, and AfaA; pfam03333|highly similar to Yersinia pestis CO92 YPO3245 and Yersinia pestis KIM y0945 | | PF03333(6) | | |
| 5033 |
|
| phosphate binding protein|ABC-type phosphate transport system, periplasmic component [Inorganic ion transport and metabolism]; COG0226|highly similar to Yersinia pestis CO92 pstS and Yersinia pestis KIM y0980. Contains Antifreeze protein, type I (Interpro|IPR000104). Contains Bacterial extracellular solute-binding protein, family 1 (Interpro|IPR006059, (GO:0006810)) | COG0226(6) | | | |
| 5034 |
|
| probable glycosyltransferase|Glycosyl transferase family 2. Diverse family, transferring sugar from UDP-glucose, UDP-N-acetyl- galactosamine, GDP-mannose or CDP-abequose, to a range of substrates including cellulose, dolichol phosphate and teichoic acids; cl01111 | | | | |
| 5035 |
|
| hypothetical protein|highly similar to Yersinia pestis CO92 YPO3089 and Yersinia pestis KIM y1089.,,, | | | | |
| 5036 |
|
| Predicted Zn-dependent hydrolases of the beta-lactamase fold|highly similar to Yersinia pestis KIM y1120, | | | | |
| 5037 |
|
| hypothetical protein|highly similar to Yersinia pestis CO92 YPO2804 and Yersinia pestis KIM y1127,,, | | | | |
| 5038 |
|
| putative membrane protein|Uncharacterized membrane-anchored protein [Function unknown]; COG4929|highly similar to Yersinia pestis CO92 YPO2802 and Yersinia pestis KIM y1129 | COG4929(6) | | | |
| 5039 |
|
| hypothetical protein|highly similar to Yersinia pestis CO92 YPO2794 and Yersinia pestis KIM y1135,,, | | | | |
| 5040 |
|
| conserved hypothetical protein|Prolyl 4-hydroxylase alpha subunit homologues. Mammalian enzymes catalyse hydroxylation of collagen, for example. Prokaryotic enzymes might catalyse hydroxylation of antibiotic peptides; smart00702|highly similar to Yersinia pestis CO92 YPO1192 and Yersinia pestis KIM y2997. | | | SM00702(5) | |
| 5041 |
|
| putative pyridoxal-dependent decarboxylase|Glutamate decarboxylase and related PLP-dependent proteins [Amino acid transport and metabolism]; COG0076|Pyridoxal-dependent decarboxylase conserved domain; pfam00282|highly similar to Yersinia pestis CO92 YPO1193 and Yersinia pestis KIM dcd. Contains Alkaline phosphatase (Interpro|IPR001952, (GO:0008152), (GO:0016302)). Contains Pyridoxal-dependent decarboxylase (Interpro|IPR002129, (GO:0006520), (GO:0016831)). Contains DeoxyUTP pyrophosphatase (Interpro|IPR001428, (GO:0006399)). Contains dCTP Deaminase (Interpro|IPR003232) | COG0076(6) | PF00282(6) | | |
| 5042 |
|
| putative transcriptional regulatory protein|Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; COG1349|helix_turn_helix, Deoxyribose operon repressor; smart00420|Bacterial regulatory proteins, deoR family; pfam00455 | COG1349(6) | PF00455(6) | SM00420(6) | |
| 5043 |
|
| hypothetical protein|highly similar to Yersinia pestis KIM y2947. Contains ATP/GTP-binding site motif A (P-loop) (Interpro|IPR001687, (GO:0005524)) | | | | |
| 5044 |
|
| hypothetical protein|highly similar to Yersinia pestis CO92 YPO1244 and Yersinia pestis KIM y2943,,, | | | | |
| 5045 |
|
| putative bacteriophage coat protein|highly similar to Yersinia pestis CO92 YPO1245 and Yersinia pestis KIM y2942, | | | | |
| 5046 |
|
| putative short chain oxidoreductase|3-ketoacyl-(acyl-carrier-protein) reductase; PRK12825 | | | | |
| 5047 |
|
| putative D-isomer specific 2-hydroxyacid dehydrogenase family protein | | PF00389(6)|PF02826(6) | | |
| 5048 |
|
| 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)|Fumarylacetoacetate (FAA) hydrolase family protein [General function prediction only]; COG3970|highly similar to Yersinia pestis CO92 YPO1289 and Yersinia pestis KIM y2895 | COG3970(6) | | | |
| 5049 |
|
| putative carbohydrate kinase|Sugar (pentulose and hexulose) kinases [Carbohydrate transport and metabolism]; COG1070|FGGY family of carbohydrate kinases, N-terminal domain. This domain adopts a ribonuclease H-like fold and is structurally related to the C-terminal domain; pfam00370|highly similar to Yersinia pestis CO92 YPO1291 and Yersinia pestis KIM y2893. Contains Carbohydrate kinase, FGGY (Interpro|IPR000577, (GO:0005975)). Contains Xylulokinase (Interpro|IPR006000, (GO:0005997)) | COG1070(6) | PF00370(6)|PF02782(6) | | |
| 5050 |
|
| putative ribose 5-phosphate isomerase|RPI_A: Ribose 5-phosphate isomerase type A (RPI_A) subfamily; RPI catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate, the first step of the non-oxidative branch of the pentose phosphate pathway; cd01398 | | | | Q66CS8(1) |
| 5051 |
|
| putative periplasmic carbohydrate-binding transport protein|ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; COG1879|highly similar to Yersinia pestis CO92 YPO1293 and Yersinia pestis KIM y2891. Contains ATP/GTP-binding site motif A (P-loop) (Interpro|IPR001687, (GO:0005524)). Contains Twin-arginine translocation pathway signal (Interpro|IPR006311) | COG1879(6)|COG4213(6) | | | |
| 5052 |
|
| putative ABC transport ATP-binding subunit|This family represents the domain I of the carbohydrate uptake proteins that transport only monosaccharides (Monos); cd03216|The pleiotropic drug resistance (PDR) family of ATP-binding cassette (ABC) transporters. PDR is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes; cd03233|highly similar to Yersinia pestis CO92 YPO1294 and Yersinia pestis KIM y2890. Contains ATP/GTP-binding site motif A (P-loop) (Interpro|IPR001687, (GO:0005524)). Contains ABC transporter (Interpro|IPR003439, (GO:0016020)). Contains AAA ATPase (Interpro|IPR003593, (GO:0000166)) | | | | |
| 5053 |
|
| putative ABC transport integral membrane subunit|Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components [Carbohydrate transport and metabolism]; COG1172|highly similar to Yersinia pestis CO92 YPO1295 and Yersinia pestis KIM y2889. Contains Bacterial inner-membrane translocator (Interpro|IPR001851, (GO:0016020)) | COG1172(6) | | | |
| 5054 |
|
| putative transport ATP-binding protein|ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components [Inorganic ion transport and metabolism / Coenzyme metabolism]; COG1120|ABC transporters, involved in the uptake of siderophores, heme, and vitamin B12, are widely conserved in bacteria and archaea. Only very few species lack representatives of the siderophore family transporters. The E; cd03214|highly similar to Yersinia pestis CO92 YPO1345 and Yersinia pestis KIM y2837. Contains ATP/GTP-binding site motif A (P-loop) (Interpro|IPR001687, (GO:0005524)). Contains ABC transporter (Interpro|IPR003439, (GO:0016020)). Contains AAA ATPase (Interpro|IPR003593, (GO:0000166)) | COG1120(6) | | | |
| 5055 |
|
| putative ABC transport protein|Protein-L-isoaspartate carboxylmethyltransferase [Posttranslational modification, protein turnover, chaperones]; COG2518|highly similar to Yersinia pestis KIM y2836 | COG2518(6) | | | |
| 5056 |
|
| hypothetical protein|Uncharacterized protein conserved in bacteria [Function unknown]; COG4408|highly similar to Yersinia pestis KIM y2835 | COG4408(6) | | | |
| 5057 |
|
| Permeases of the drug/metabolite transporter (DMT) superfamily|Integral membrane protein DUF6. This family includes many hypothetical membrane proteins of unknown function. Many of the proteins contain two copies of the aligned region; pfam00892|highly similar to Yersinia pestis KIM y2834. Contains Protein of unknown function DUF6 (Interpro|IPR000620). Contains Blood group Rhesus C/E and D polypeptide (Interpro|IPR002229) | COG0697(2) | PF00892(6) | | |
| 5058 |
|
| hypothetical protein|Glycosyltransferase involved in LPS biosynthesis [Cell envelope biogenesis, outer membrane]; COG3306|highly similar to Yersinia pestis CO92 YPO1382 and Yersinia pestis KIM y2791. Contains Glycosyl transferase, family 25 (Interpro|IPR002654, (GO:0009103)) | COG3306(6) | | | |
| 5059 |
|
| putative exported protein|YadA-like C-terminal region. This region represents the C-terminal 120 amino acids of a family of surface-exposed bacterial proteins. YadA, an adhesin from Yersinia, was the first member of this family to be characterised. UspA2 from Moraxella was second; pfam03895|highly similar to Yersinia pestis CO92 YPO1387 and Yersinia pestis KIM y2786 | | PF03895(6) | | |
| 5060 |
|
| putative exported protein|highly similar to Yersinia pestis CO92 YPO1388 and Yersinia pestis KIM y2785, | | | | |
| 5061 |
|
| putative short chain dehydrogenase|3-ketoacyl-(acyl-carrier-protein) reductase; PRK05653 | | | | |
| 5062 |
|
| hypothetical protein|highly similar to Yersinia pestis CO92 YPO1453 and Yersinia pestis KIM y2716, | | | | |
| 5063 |
|
| putative beta-ketoacyl-[acyl-carrier-protein] synthase|3-oxoacyl-(acyl-carrier-protein) synthase [Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism]; COG0304|Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible for the elongation steps in fatty acid biosynthesis; cd00834 | COG0304(6) | | | |
| 5064 |
|
| putative beta-ketoacyl-[acyl-carrier-protein] reductase|3-ketoacyl-(acyl-carrier-protein) reductase; PRK05653, | | | | |
| 5065 |
|
| putative hydroxymethylglutaryl-coenzyme A synthase|3-hydroxy-3-methylglutaryl CoA synthase [Lipid metabolism]; COG3425|'initiating' condensing enzymes are a subclass of decarboxylating condensing enzymes, including beta-ketoacyl [ACP] synthase, type III and polyketide synthases, type III, which include chalcone synthase and related enzymes; cd00827|highly similar to Yersinia pestis CO92 YPO1457 and Yersinia pestis KIM pksG. Contains Hydroxymethylglutaryl-coenzyme A synthase (Interpro|IPR000590, (GO:0006084)). Contains ATP/GTP-binding site motif A (P-loop) (Interpro|IPR001687, (GO:0005524)) | COG3425(6) | | | |
| 5066 |
|
| putative enoyl-CoA hydratase|Enoyl-CoA hydratase/isomerase family. This family contains a diverse set of enzymes including: Enoyl-CoA hydratase. Napthoate synthase. Carnitate racemase. 3-hydoxybutyryl-CoA dehydratase. Dodecanoyl-CoA delta-isomerase; pfam00378|highly similar to Yersinia pestis CO92 YPO1458 and Yersinia pestis KIM y2711. Contains Enoyl-CoA hydratase/isomerase (Interpro|IPR001753, (GO:0008152)) | | PF00378(6) | | |
| 5067 |
|
| putative polyketide biosynthesis enoyl-coa hydratase|Enoyl-CoA hydratase/isomerase family. This family contains a diverse set of enzymes including: Enoyl-CoA hydratase. Napthoate synthase. Carnitate racemase. 3-hydoxybutyryl-CoA dehydratase. Dodecanoyl-CoA delta-isomerase; pfam00378|highly similar to Yersinia pestis KIM y2710. Contains Enoyl-CoA hydratase/isomerase (Interpro|IPR001753, (GO:0008152)) | | PF00378(6) | | |
| 5068 |
|
| putative short chain dehydrogenase|3-ketoacyl-(acyl-carrier-protein) reductase; PRK12825|highly similar to Yersinia pestis CO92 YPO1460 and Yersinia pestis KIM y2709. Contains Short-chain dehydrogenase/reductase SDR (Interpro|IPR002198, (GO:0008152), (GO:0016491)). Contains Glucose/ribitol dehydrogenase (Interpro|IPR002347, (GO:0008152), (GO:0016491)) | | | | |
| 5069 |
|
| hypothetical protein|highly similar to Yersinia pestis CO92 YPO1461 and Yersinia pestis KIM y2708,,, | | | | |
| 5070 |
|
| putative acyl transferase|(acyl-carrier-protein) S-malonyltransferase [Lipid metabolism]; COG0331|highly similar to Yersinia pestis CO92 YPO1463 and Yersinia pestis KIM y2707. Contains Acyl transferase domain (Interpro|IPR001227, (GO:0008152), (GO:0016740)) | COG0331(6) | | | |
| 5071 |
|
| hypothetical protein|highly similar to Yersinia pestis CO92 YPO1490 and Yersinia pestis KIM y2678,,, | | | | |
| 5072 |
|
| hypothetical protein|highly similar to Yersinia pestis CO92 YPO1492 and Yersinia pestis KIM y2676.,,, | | | | |
| 5073 |
|
| putative siderophore biosynthetic enzyme|Lysine/ornithine N-monooxygenase [Secondary metabolites biosynthesis, transport, and catabolism]; COG3486|highly similar to Yersinia pestis CO92 alcA and Yersinia pestis KIM ysuI | COG3486(6) | | | |
| 5074 |
|
| putative iron-siderophore transport system, periplasmic binding protein|Fe3+-siderophore binding domain FhuD. These proteins have been shown to function as initial receptors in ABC transport of Fe3+-siderophores in many eubacterial species; cd01146 | COG0614(6) | | | |
| 5075 |
|
| putative membrane protein|Predicted thiol-disulfide oxidoreductase [General function prediction only]; COG3011|highly similar to Yersinia pestis CO92 YPO1564 and Yersinia pestis KIM y2601. | COG3011(6) | | | |
| 5076 |
|
| putative sugar transporter|putative sialic acid transporter; PRK03893|Major Facilitator Superfamily; pfam07690|Sugar (and other) transporter; pfam00083 | | PF07690(6)|PF00083(6) | | |
| 5077 |
|
| putative exported protein|highly similar to Yersinia pestis CO92 YPO1574 and Yersinia pestis KIM y2590 | | | | |
| 5078 |
|
| Predicted transcriptional regulators|highly similar to Yersinia pestis CO92 YPO1849 and Yersinia pestis KIM y2457., | COG4190(6) | | | |
| 5079 |
|
| hypothetical protein|highly similar to Yersinia pestis CO92 YPO1850 and Yersinia pestis KIM y2456,,, | | | | |
| 5080 |
|
| phage-related protein|Phage P2 baseplate assembly protein gpV [General function prediction only]; COG4540|highly similar to Yersinia pestis CO92 YPO1881 and Yersinia pestis KIM y2429. Contains Phage-related baseplate assembly protein (Interpro|IPR006807) | COG4540(6) | | | |
| 5081 |
|
| conserved hypothetical protein|Uncharacterized protein conserved in bacteria [Function unknown]; COG3514|highly similar to Yersinia pestis CO92 YPO1882 and Yersinia pestis KIM y2427 | COG3514(6) | | | |
| 5082 |
|
| putative exported solute-binding protein|ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; COG1653|highly similar to Yersinia pestis CO92 YPO1893 and Yersinia pestis KIM y2417. Contains Bacterial extracellular solute-binding protein, family 1 (Interpro|IPR006059, (GO:0006810)) | COG1653(6) | | | |
| 5083 |
|
| Anthranilate/para-aminobenzoate synthases component I|chorismate binding enzyme. This family includes the catalytic regions of the chorismate binding enzymes anthranilate synthase, isochorismate synthase, aminodeoxychorismate synthase and para-aminobenzoate synthase; pfam00425 | | PF00425(6) | | |
| 5084 |
|
| hypothetical protein|highly similar to Yersinia pestis CO92 YPO1984 and Yersinia pestis KIM y2327,,, | | | | |
| 5085 |
|
| hypothetical protein|highly similar to Yersinia pestis CO92 YPO1994 and Yersinia pestis KIM y2316,,, | | | | |
| 5086 |
|
| hypothetical protein|highly similar to Yersinia pestis CO92 YPO1995 and Yersinia pestis KIM y2315,,, | | | | |
| 5087 |
|
| hypothetical protein|highly similar to Yersinia pestis CO92 YPO1996 and Yersinia pestis KIM y2313,,, | | | | |
| 5088 |
|
| putative exported protein|highly similar to Yersinia pestis CO92 YPO1997 and Yersinia pestis KIM y2312., | | | | |
| 5089 |
|
| putative exported protein|flavodoxin; PRK06934|highly similar to Yersinia pestis CO92 YPO2003 and Yersinia pestis KIM y2305.,,, | | | | |
| 5090 |
|
| putative ABC transporter periplasmic binding protein|ABC-type uncharacterized transport system, periplasmic component [General function prediction only]; COG4134|highly similar to Yersinia pestis KIM y2281. Contains Bacterial extracellular solute-binding protein, family 1 (Interpro|IPR006059, (GO:0006810)) | COG4134(6) | | | |
| 5091 |
|
| hypothetical phage protein|highly similar to Yersinia pestis CO92 YPO2139 and Yersinia pestis KIM y2181., | | | | |
| 5092 |
|
| attachment invasion locus protein precursor|outer membrane protein X; PRK09408 | | | | |
| 5093 |
|
| hypothetical protein|highly similar to Yersinia pestis CO92 YPO2220 and Yersinia pestis KIM y2062,,, | | | | |
| 5094 |
|
| putative lipoprotein|predicted lipoproteinC; PRK10215|highly similar to Yersinia pestis CO92 YPO1674 and Yersinia pestis KIM y1836., | | | | |
| 5095 |
|
| putative LysR-family transcriptional regulator|DNA-binding transcriptional activator GcvA; PRK11139|Bacterial regulatory helix-turn-helix protein, lysR family; pfam00126|LysR substrate binding domain. The structure of this domain is known and is similar to the periplasmic binding proteins; pfam03466 | | PF00126(6)|PF03466(6) | | |
| 5096 |
|
| conserved hypothetical protein|Formaldehyde-activating enzyme nesessary for methanogenesis [Energy production and conversion]; COG1795|highly similar to Yersinia pestis CO92 YPO2460 and Yersinia pestis KIM y1729 | COG1795(6) | | | |
| 5097 |
|
| putative exported protein|highly similar to Yersinia pestis CO92 YPO2471 and Yersinia pestis KIM y1718, | | | | |
| 5098 |
|
| putative exported protein|highly similar to Yersinia pestis CO92 YPO2472 and Yersinia pestis KIM y1717., | | | | |
| 5099 |
|
| hypothetical protein|Protein of unknown function (DUF1861). This hypothetical protein, found in bacteria and in the eukaryote Leishmania, has no known function; pfam08950|highly similar to Yersinia pestis CO92 YPO2473 and Yersinia pestis KIM y1716 | | PF08950(6) | | |
| 5100 |
|
| Predicted glycosylase|Predicted glycosylase [Carbohydrate transport and metabolism]; COG2152|highly similar to Yersinia pestis CO92 YPO2474 and Yersinia pestis KIM y1715, | COG2152(6) | | | |
| 5101 |
|
| sugar ABC transporter, permease protein|ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; COG0395|highly similar to Yersinia pestis CO92 YPO2475 and Yersinia pestis KIM y1714. Contains Binding-protein-dependent transport systems inner membrane component (Interpro|IPR000515, (GO:0016020)) | COG0395(6) | | | |
| 5102 |
|
| sugar ABC transporter, permease protein|ABC-type sugar transport systems, permease components [Carbohydrate transport and metabolism]; COG1175|highly similar to Yersinia pestis CO92 YPO2476 and Yersinia pestis KIM y1713. Contains Binding-protein-dependent transport systems inner membrane component (Interpro|IPR000515, (GO:0016020)) | COG1175(6) | | | |
| 5103 |
|
| LacI-family transcriptional regulatory protein|Transcriptional regulators [Transcription]; COG1609|helix_turn _helix lactose operon repressor; smart00354|highly similar to Yersinia pestis CO92 YPO2478 and Yersinia pestis KIM y1711. Contains Bacterial regulatory protein LacI, HTH motif (Interpro|IPR000843, (GO:0006355)). Contains Periplasmic binding protein/LacI transcriptional regulator (Interpro|IPR001761) | COG1609(6) | | SM00354(6) | |
| 5104 |
|
| putative exported protein|highly similar to Yersinia pestis CO92 YPO2481 and Yersinia pestis KIM y1705., | | | | |
| 5105 |
|
| putative LacI-family transcriptional regulatoryprotein|Transcriptional regulators [Transcription]; COG1609|helix_turn _helix lactose operon repressor; smart00354|highly similar to Yersinia pestis CO92 YPO2498 and Yersinia pestis KIM y1690. Contains Bacterial regulatory protein LacI, HTH motif (Interpro|IPR000843, (GO:0006355)). Contains Periplasmic binding protein/LacI transcriptional regulator (Interpro|IPR001761) | COG1609(6) | | SM00354(6) | |
| 5106 |
|
| putative exported protein|Cytochrome c biogenesis factor [Posttranslational modification, protein turnover, chaperones]; COG4235|Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi, pl; cd00189|Uncharacterized conserved protein [Function unknown]; COG1434|highly similar to Yersinia pestis CO92 YPO2511 and Yersinia pestis KIM y1676. Contains TPR repeat (Interpro|IPR001440) | COG4235(6)|COG1434(6) | | | |
| 5107 |
|
| conserved hypothetical protein|highly similar to Yersinia pestis CO92 YPO2530 and Yersinia pestis KIM y1658, | | | | |
| 5108 |
|
| putative exported protein, | | | | |
| 5109 |
|
| hypothetical protein|highly similar to Yersinia pestis CO92 YPO2963 and Yersinia pestis KIM y1521,,, | | | | |
| 5110 |
|
| putative iron-sulphur protein|ferredoxin-type protein; PRK10194|highly similar to Yersinia pestis CO92 YPO2969 and Yersinia pestis KIM y1515., | | | | |
| 5111 |
|
| putative pyridine nucleotide-disulphide oxidoreductase|coenzyme A disulfide reductase; PRK09564|Pyridine nucleotide-disulphide oxidoreductase. This family includes both class I and class II oxidoreductases and also NADH oxidases and peroxidases. This domain is actually a small NADH binding domain within a larger FAD binding domain; pfam00070|Member of the Rhodanese Homology Domain superfamily; cd01524 | | PF00070(6)|PF02852(6) | | |
| 5112 |
|
| putative permease|Na+/proline symporter [Amino acid transport and metabolism / General function prediction only]; COG0591|highly similar to Yersinia pestis CO92 YPO3002 and Yersinia pestis KIM y1478. Contains Na+/solute symporter (Interpro|IPR001734, (GO:0016020)) | COG0591(6)|COG4147(6) | | | |
| 5113 |
|
| putative membrane protein|Uncharacterized protein containing a von Willebrand factor type A (vWA) domain [General function prediction only]; COG2304|highly similar to Yersinia pestis CO92 YPO3007 and Yersinia pestis KIM y1474. Contains Von Willebrand factor, type A (Interpro|IPR002035) | COG2304(6) | | | |
| 5114 |
|
| putative response regulator|Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; COG0745|Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; contains; cd00156|highly similar to Yersinia pestis KIM y1472. Contains Response regulator receiver (Interpro|IPR001789, (GO:0006355)). Contains Transcriptional regulatory protein, C terminal (Interpro|IPR001867, (GO:0006355)) | COG0745(6) | | | |
| 5115 |
|
| putative autotransporter|Type V secretory pathway, adhesin AidA [Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion]; COG3468|Pertactin-like passenger domains (virulence factors), C-terminal, subgroup 1, of autotransporter proteins of the type V secretion system of Gram-negative bacteria; cd01343|Autotransporter beta-domain. Secretion of protein products occurs by a number of different pathways in bacteria. One of these pathways known as the type V pathway was first described for the IgA1 protease; pfam03797|highly similar to Yersinia pestis CO92 YPO3028 and Yersinia pestis KIM y1454. Contains Pertactin virulence factor, C-terminal (Interpro|IPR003991, (GO:0007155)). Contains Pertactin domain (Interpro|IPR004899). Contains Autotransporter beta-domain (Interpro|IPR005546). Contains Outer membrane autotransporter barrel (Interpro|IPR006315) | COG3468(6) | PF03797(6) | | |
| 5116 |
|
| hypothetical protein|highly similar to Yersinia pestis CO92 YPO3044 and Yersinia pestis KIM y1438,,, | | | | |
| 5117 |
|
| putative phosphate transport ATP-binding protein|ABC-type phosphate transport system, ATPase component [Inorganic ion transport and metabolism]; COG1117|Phosphate uptake is of fundamental importance in the cell physiology of bacteria because phosphate is required as a nutrient. The Pst system of E. coli comprises four distinct subunits encoded by the pstS, pstA, pstB, and pstC genes; cd03260|highly similar to Yersinia pestis CO92 pstb and Yersinia pestis KIM pstB. Contains ATP/GTP-binding site motif A (P-loop) (Interpro|IPR001687, (GO:0005524)). Contains ABC transporter (Interpro|IPR003439, (GO:0016020)). Contains AAA ATPase (Interpro|IPR003593, (GO:0000166)) | COG1117(6) | | | Q668E1(1) |
| 5118 |
|
| putative phosphate transport system permease|ABC-type phosphate transport system, auxiliary component [Inorganic ion transport and metabolism]; COG4985 | COG4985(6)|COG0581(6) | | | |
| 5119 |
|
| putative ABC transporter permease|Binding-protein-dependent transport system inner membrane component. The alignments cover the most conserved region of the proteins, which is thought to be located in a cytoplasmic loop between two transmembrane domains. The members of this family have...; cl00427 | | | | |
| 5120 |
|
| putative ABC transporter permease|ABC-type spermidine/putrescine transport system, permease component I [Amino acid transport and metabolism]; COG1176|highly similar to Yersinia pestis CO92 YPO2842 and Yersinia pestis KIM y1392. Contains Binding-protein-dependent transport systems inner membrane component (Interpro|IPR000515, (GO:0016020)) | COG1176(6) | | | |
| 5121 |
|
| putative transport system periplasmic protein|Bacterial extracellular solute-binding protein. This family also includes the bacterial extracellular solute-binding protein family POTD/POTF; pfam01547|highly similar to Yersinia pestis CO92 YPO2843 and Yersinia pestis KIM y1391. Contains Bacterial periplasmic spermidine/putrescine-binding protein (Interpro|IPR001188, (GO:0030288)) | COG0687(6) | PF01547(6) | | |
| 5122 |
|
| putative membrane protein|Enterobacterial putative membrane protein (DUF943). This family consists of several hypothetical putative membrane proteins from Escherichia coli, Yersinia pestis and Salmonella typhi; pfam06092 | | PF06092(6) | | |
| 5123 |
|
| putative exported protein|highly similar to Yersinia pestis CO92 YPO2918 and Yersinia pestis KIM y1311., | | | | |
| 5124 |
|
| putative membrane protein|highly similar to Yersinia pestis CO92 YPO0807 and Yersinia pestis KIM y3196, | | | | |
| 5125 |
|
| sugar transport system permease|ribose ABC transporter permease protein; PRK09512 | | | | |
| 5126 |
|
| sugar-binding periplasmic protein|ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; COG1879|highly similar to Yersinia pestis CO92 YPO0860 and Yersinia pestis KIM y3245. Contains Periplasmic binding protein/LacI transcriptional regulator (Interpro|IPR001761) | COG1879(6)|COG4213(6) | | | |
| 5127 |
|
| conserved hypothetical protein|highly similar to Yersinia pestis CO92 YPO0870 and Yersinia pestis KIM y3254. Contains Beta and gamma crystallin (Interpro|IPR001064), | | | | |
| 5128 |
|
| hypothetical protein|Pyocin large subunit [General function prediction only]; COG5529|highly similar to Yersinia pestis CO92 YPO0873 and Yersinia pestis KIM y3255 | COG5529(6) | | | |
| 5129 |
|
| hypothetical protein|highly similar to Yersinia pestis CO92 YPO0875 and Yersinia pestis KIM y3257.,,, | | | | |
| 5130 |
|
| putative virulence determinant|Peptidase M10 serralysin C terminal. Serralysins are peptidases related to mammalian matrix metallopeptidases (MMPs); pfam08548|highly similar to Yersinia pestis CO92 YPO0947 and Yersinia pestis KIM y3333. Contains Integrins alpha chain (Interpro|IPR000413, (GO:0008305)). Contains Hemolysin-type calcium-binding region (Interpro|IPR001343, (GO:0005509)). Contains Bacterial RTX cytolytic toxin, protein A (Interpro|IPR003995, Cellular Component: extracellular (GO:0005576), (GO:0009405), (GO:0015484)). Contains RTX (repeat in structural toxin) (Interpro|IPR006661) | | PF08548(6) | | |
| 5131 |
|
| putative sugar transport system permeaseprotein|Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components [Carbohydrate transport and metabolism]; COG1172|highly similar to Yersinia pestis CO92 YPO0957 and Yersinia pestis KIM y3344. Contains Bacterial extracellular solute-binding protein, family 3 (Interpro|IPR001638, (GO:0030288)). Contains Bacterial inner-membrane translocator (Interpro|IPR001851, (GO:0016020)) | COG1172(6) | | | |
| 5132 |
|
| putative sugar ABC transporter periplasmicbinding protein|ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; COG1879|highly similar to Yersinia pestis CO92 YPO0959 and Yersinia pestis KIM y3346. Contains Periplasmic binding protein/LacI transcriptional regulator (Interpro|IPR001761) | COG1879(6)|COG4213(6) | | | |
| 5133 |
|
| putative lipoprotein|highly similar to Yersinia pestis CO92 YPO0982 and Yersinia pestis KIM y3371,,, | | | | |
| 5134 |
|
| N-acylhomoserine lactone synthase YspI|Autoinducer synthetase; pfam00765|highly similar to Yersinia pestis CO92 yspI and Yersinia pestis KIM ytbI. Contains Autoinducer synthesis protein (Interpro|IPR001690, (GO:0007165)) | | PF00765(6) | | |
| 5135 |
|
| quorum-sensing transcriptional regulator|Autoinducer binding domain. This domain is found a a large family of transcriptional regulators. This domain specifically binds to autoinducer molecules; pfam03472|helix_turn_helix, Lux Regulon; lux regulon (activates the bioluminescence operon; smart00421|highly similar to Yersinia pestis CO92 yspR and Yersinia pestis KIM ytbR. Contains Bacterial regulatory protein, LuxR family (Interpro|IPR000792, (GO:0006355)). Contains Autoinducer binding domain (Interpro|IPR005143) | | PF03472(6) | SM00421(6) | |
| 5136 |
|
| putative exported protein|Predicted peptidase [General function prediction only]; COG4099|highly similar to Yersinia pestis CO92 YPO0986 and Yersinia pestis KIM y3376. Contains Esterase/lipase/thioesterase, active site (Interpro|IPR000379, (GO:0003824)). Contains Twin-arginine translocation pathway signal (Interpro|IPR006311) | COG4099(6)|COG0400(6) | | | |
| 5137 |
|
| putative exported protein|Intradiol dioxygenase supgroup. Intradiol dioxygenases catalyze the critical ring-cleavage step in the conversion of catecholate derivatives to citric acid cycle intermediates; cd03457 | | | | |
| 5138 |
|
| hypothetical protein|highly similar to Yersinia pestis KIM y3539.,, | COG3728(1) | | | |
| 5139 |
|
| Predicted protein-disulfide isomerase|DsbA family, FrnE-like subfamily; composed of uncharacterized proteins containing a CXXC motif with similarity to DsbA and FrnE; cd03025 | | | | |
| 5140 |
|
| putative translational inhibitor protein|YjgF, YER057c, and UK114 belong to a large family of proteins present in bacteria, archaea, and eukaryotes with no definitive function; cd00448|highly similar to Yersinia pestis CO92 YPO0627 and Yersinia pestis KIM y3551. Contains YjgF-like protein (Interpro|IPR006056). Contains Endoribonuclease L-PSP (Interpro|IPR006175) | | | | |
| 5141 |
|
| hypothetical protein|highly similar to Yersinia pestis CO92 YPO0625 and Yersinia pestis KIM y3553, | | | | |
| 5142 |
|
| hypothetical protein|highly similar to Yersinia pestis CO92 YPO0621 and Yersinia pestis KIM y3556.,,, | | | | |
| 5143 |
|
| hypothetical protein|highly similar to Yersinia pestis KIM y3563, | | | | |
| 5144 |
|
| putative permease|ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; COG0395|highly similar to Yersinia pestis CO92 YPO0614 and Yersinia pestis KIM y3564. Contains Binding-protein-dependent transport systems inner membrane component (Interpro|IPR000515, (GO:0016020)) | COG0395(6) | | | |
| 5145 |
|
| putative permease protein|ABC-type sugar transport systems, permease components [Carbohydrate transport and metabolism]; COG1175|highly similar to Yersinia pestis CO92 YPO0613 and Yersinia pestis KIM y3565. Contains Binding-protein-dependent transport systems inner membrane component (Interpro|IPR000515, (GO:0016020)). Contains Neutral zinc metallopeptidases, zinc-binding region (Interpro|IPR006025, (GO:0008237), (GO:0008270)) | COG1175(6) | | | |
| 5146 |
|
| putative sugar binding protein|ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; COG1653|highly similar to Yersinia pestis CO92 YPO0612 and Yersinia pestis KIM y3566. Contains Bacterial extracellular solute-binding protein, family 1 (Interpro|IPR006059, (GO:0006810)) | COG1653(6) | | | |
| 5147 |
|
| LacI-family regulatory protein|Transcriptional regulators [Transcription]; COG1609|helix_turn _helix lactose operon repressor; smart00354|highly similar to Yersinia pestis CO92 YPO0611 and Yersinia pestis KIM y3567. Contains Bacterial regulatory protein LacI, HTH motif (Interpro|IPR000843, (GO:0006355)). Contains Periplasmic binding protein/LacI transcriptional regulator (Interpro|IPR001761) | COG1609(6) | | SM00354(6) | |
| 5148 |
|
| hypothetical protein|Cellobiose phosphorylase [Carbohydrate transport and metabolism]; COG3459|highly similar to Yersinia pestis CO92 YPO0610 and Yersinia pestis KIM y3568, | COG3459(6) | | | |
| 5149 |
|
| putative membrane protein|Uncharacterized protein conserved in bacteria [Function unknown]; COG5368|highly similar to Yersinia pestis CO92 YPO0608 and Yersinia pestis KIM y3570 | COG5368(6) | | | |
| 5150 |
|
| putative autotransporter protein|Autotransporter beta-domain. Secretion of protein products occurs by a number of different pathways in bacteria. One of these pathways known as the type V pathway was first described for the IgA1 protease; pfam03797|highly similar to Yersinia pestis CO92 yapF and Yersinia pestis KIM y3573. Contains Autotransporter beta-domain (Interpro|IPR005546). Contains Outer membrane autotransporter barrel (Interpro|IPR006315) | | PF03797(6) | | |
| 5151 |
|
| putative exported protein, | | | | |
| 5152 |
|
| putative lysR-family transcriptional regulatory protein|Bacterial regulatory helix-turn-helix protein, lysR family; pfam00126|highly similar to Yersinia pestis CO92 YPO3682 and Yersinia pestis KIM y0181. Contains Bacterial regulatory protein LysR, HTH motif (Interpro|IPR000847, (GO:0006355)) | | PF00126(6) | | |
| 5153 |
|
| putative exported protein|highly similar to Yersinia pestis CO92 YPO3675 and Yersinia pestis KIM y0188., | | | | |
| 5154 |
|
| hypothetical protein|highly similar to Yersinia pestis CO92 YPO3652 and Yersinia pestis KIM y0215, | | | | |
| 5155 |
|
| putative metabolite transport protein|shikimate transporter; PRK09952|highly similar to Yersinia pestis CO92 YPO3650 and Yersinia pestis KIM y0217. Contains Sodium:dicarboxylate symporter (Interpro|IPR001991, (GO:0016020)). Contains General substrate transporter (Interpro|IPR005828, (GO:0016020)). Contains Sugar transporter superfamily (Interpro|IPR005829, (GO:0016020)). Contains Major facilitator superfamily (MFS) (Interpro|IPR007114), | | | | |
| 5156 |
|
| Zn-dependent hydrolases, including glyoxylases|highly similar to Yersinia pestis CO92 YPO3647 and Yersinia pestis KIM y0220. Contains Beta-lactamase-like (Interpro|IPR001279) | COG0491(6) | | | |
| 5157 |
|
| putative phosphosugar isomerase/binding protein|Predicted sugar phosphate isomerase involved in capsule formation [Cell envelope biogenesis, outer membrane]; COG0794|highly similar to Yersinia pestis CO92 YPO3638 and Yersinia pestis KIM y0230. Contains Sugar isomerase (SIS) (Interpro|IPR001347, (GO:0005975)) | COG0794(6) | | | |
| 5158 |
|
| hypothetical protein|highly similar to Yersinia pestis KIM y0237. Contains TonB-dependent receptor protein (Interpro|IPR000531, (GO:0016020)), | | | | |
| 5159 |
|
| hypothetical protein|highly similar to Yersinia pestis CO92 YPO3735 and Yersinia pestis KIM y0495.,,, | | | | |
| 5160 |
|
| Permeases of the major facilitator superfamily|Protein of unknown function (DUF1240). This family consists of a number of hypothetical putative membrane proteins which seem to be specific to Yersinia pestis. The function of this family is unknown; pfam06836 | | PF06836(6) | | |
| 5161 |
|
| hypothetical protein|highly similar to Yersinia pestis CO92 YPO3951 and Yersinia pestis KIM y3878, | | | | |
| 5162 |
|
| putative membrane protein|highly similar to Yersinia pestis CO92 YPO4020 and Yersinia pestis KIM y4041. Contains Protein of unknown function DUF6 (Interpro|IPR000620). Contains Tetracycline resistance protein TetB (Interpro|IPR001411, (GO:0016021)), | | | | |
| 5163 |
|
| hypothetical protein|highly similar to Yersinia pestis KIM y4083, | | | | |
| 5164 |
|
| putative exported protein|Similar to Yersinia pestis putative membrane protein ypo0149 SWALL:Q8ZJF9 (EMBL:AJ414141) (122 aa) fasta scores: E(): 4.2e-14, 39.42 38d in 104 aa,, | | | | |
| 5165 |
|
| putative tight adherance operon protein|Flp pilus assembly protein TadG [Intracellular trafficking and secretion]; COG4961 | COG4961(7) | | | |
| 5166 |
|
| conserved hypothetical protein | | | | |
| 5167 |
|
| general secretion pathway protein J precursor|Type II secretory pathway, component PulJ [Intracellular trafficking and secretion]; COG4795 | COG4795(6) | | | |
| 5168 |
|
| general secretion pathway protein L|Type II secretory pathway, component PulL [Intracellular trafficking and secretion]; COG3297 | COG3297(7) | | | |
| 5169 |
|
| conserved hypothetical protein | | | | |
| 5170 |
|
| conserved hypothetical protein|Similar to Salmonella typhi hypothetical protein STY4108 SWALL:Q8Z2E1 (EMBL:AL627280) (68 aa) fasta scores: E(): 0.31, 34 38d in 50 aa, and to Yersinia pestis hypothetical protein YPO2590 SWALL:Q8ZDH8 (EMBL:AJ414153) (64 aa) fasta scores: E(): 2.5e-16, 82.54 38d in 63 aa, | | | | |
| 5171 |
|
| adenylate cyclase 2|Adenylate cyclase, class 2 (thermophilic) [Nucleotide transport and metabolism]; COG1437 | COG1437(7) | | | |
| 5172 |
|
| putative membrane protein|Poor database matches. C-terminal region is similar to Yersinia pestis putative membrane protein YPO1518 SWALL:Q8ZG02 (EMBL:AJ414148) (175 aa) fasta scores: E(): 7.8e-41, 63.42 38d in 175 aa | | | | |
| 5173 |
|
| conserved hypothetical protein,,, | | | | |
| 5174 |
|
| conserved hypothetical protein | | | | |
| 5175 |
|
| probable pili assembly chaperone|P pilus assembly protein, chaperone PapD [Cell motility and secretion / Intracellular trafficking and secretion]; COG3121|Gram-negative pili assembly chaperone, N-terminal domain. C2 domain-like beta-sandwich fold; pfam00345 | COG3121(1) | PF00345(6)|PF02753(6) | | |
| 5176 |
|
| fimbrial protein|Fimbrial protein; pfam00419,, | COG3539(1) | PF00419(5) | | |
| 5177 |
|
| putative membrane protein|Arabinose efflux permease [Carbohydrate transport and metabolism]; COG2814|Major Facilitator Superfamily; pfam07690 | COG2814(1) | PF07690(6) | | |
| 5178 |
|
| putative cytochrome|Cytochrome c553 [Energy production and conversion]; COG2863|Similar to Helicobacter pylori J99 cytochrome C-553 precursor jhp1148 SWALL:C553_HELPJ (SWALL:Q9ZJZ9) (96 aa) fasta scores: E(): 0.0035, 34.69 38d in 98 aa and to Yersinia pestis putative cytochrome Ypo1948 SWALL:Q8ZF20 (EMBL:AJ414150) (103 aa) fasta scores: E(): 1.7e-28, 79.8 id in 104 aa | COG2863(6) | | | |
| 5179 |
|
| haemin storage system, HmsS protein | | | | |
| 5180 |
|
| putative LysR-family transcriptional regulatory protein|Transcriptional regulator [Transcription]; COG0583|Bacterial regulatory helix-turn-helix protein, lysR family; pfam00126 | COG0583(1) | PF00126(7) | | |
| 5181 |
|
| conserved hypothetical protein | | | | |
| 5182 |
|
| putative AraC-family transcriptional regulatory protein|DNA-binding transcriptional activator MarA; PRK11511|Bacterial regulatory helix-turn-helix proteins, AraC family; pfam00165 | | PF00165(5) | SM00342(5) | |
| 5183 |
|
| putative exported protein|Uncharacterized secreted protein [Function unknown]; COG5430|Also similar to YE1860 35.795 38dentity in 176 aa overlap and YE1859 26.519 38dentity in 181 aa overlap | COG5430(7) | | | |
| 5184 |
|
| putative exported protein|Uncharacterized secreted protein [Function unknown]; COG5430|Also similar to YE1861 27.473 38dentity in 182 aa overlap and YE1860 34.463 38dentity in 177 aa overlap | COG5430(7) | | | |
| 5185 |
|
| conserved hypothetical protein|PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels; cd00130|FOG: PAS/PAC domain [Signal transduction mechanisms]; COG2202|Diguanylate-cyclase (DGC) or GGDEF domain: Originally named after a conserved residue pattern, and initially described as domain of unknown function 1 (DUF1); cd01949 | COG2202(6) | PF08448(5), PF00989(1) | | |
| 5186 |
|
| putative membrane protein, | | | | |
| 5187 |
|
| conserved hypothetical protein | COG1359(6) | | | |
| 5188 |
|
| putative hydrolase|Phosphoserine phosphatase [Amino acid transport and metabolism]; COG0560 | COG0560(7) | | | |
| 5189 |
|
| conserved hypothetical protein | | | | |
| 5190 |
|
| hypothetical protein|Similar to the N-terminus of Halomonas elongata MobD protein SWALL:Q9K589 (EMBL:AJ243735) (73 aa) fasta scores: E(): 0.053, 35.59 38d in 59 aa | | PF04899(2) | | |
| 5191 |
|
| putative exported protein | | | | |
| 5196 |
|
| hypothetical protein|similar to |16123243|ref|NP_406556.1| hypothetical protein [Yersinia pestis] | | | | |
| 5198 |
|
| putative toxin subunit|highly similar to Yersinia pestis KIM tcbA. Contains Phosphopantetheine attachment site (Interpro|IPR006162) | | | | |
| 5201 |
|
| hypothetical protein, | | | | |
| 5202 |
|
| putative transcriptional regulator (LysR family)|Transcriptional regulator [Transcription]; COG0583|Bacterial regulatory helix-turn-helix protein, lysR family; pfam00126|LysR substrate binding domain. The structure of this domain is known and is similar to the periplasmic binding proteins; pfam03466 | COG0583(6) | PF00126(6)|PF03466(6) | | |
| 5203 |
|
| ATP-binding component of histidine transport|ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; COG1126|HisP and GlnQ are the ATP-binding components of the bacterial periplasmic histidine and glutamine permeases, repectively. Histidine permease is a multisubunit complex containing the HisQ and HisM integral membrane subunits and two copies of HisP; cd03262 | COG1126(7) | | | |
| 5218 |
|
| hypothetical protein|VWA subfamily: Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF); cd01464 | | | | |
| 5219 |
|
| putative kinase protein|Serine/threonine protein kinase [General function prediction only / Signal transduction mechanisms / Transcription / DNA replication, recombination, and repair]; COG0515|Serine/Threonine protein kinases, catalytic domain. Phosphotransferases of the serine or threonine-specific kinase subfamily; cd00180|highly similar to Yersinia pestis CO92 YPO0592 and Yersinia pestis KIM y3587. Contains Protein kinase (Interpro|IPR000719, (GO:0006468)). Contains Tyrosine protein kinase (Interpro|IPR001245, (GO:0006468)) | COG0515(6) | | | |
| 5227 |
|
| probable peptidase|Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases [Amino acid transport and metabolism]; COG0624|highly similar to Yersinia pestis CO92 YPO1009 and Yersinia pestis KIM y3403. Contains Peptidase M20/M25/M40 (Interpro|IPR002933, (GO:0006508), (GO:0008237)) | COG0624(6) | | | |
| 5254 |
|
| putative phage protein|Phage-related protein [Function unknown]; COG4718 | COG4718(5) | | | |
| 5255 |
|
| putative phage protein|Phage-related protein [Function unknown]; COG4672 | COG4672(5) | | | |
| 5309 |
|
| putative fimbrial componenet|highly similar to Yersinia pestis KIM y1872. Contains Fimbrial protein (Interpro|IPR000259, (GO:0009289)) | COG3539(5) | | | |
| 5319 |
|
| hemin uptake protein|Hemin uptake protein [Inorganic ion transport and metabolism]; COG4256|Previously sequenced as: Yersinia enterocolitica hemin uptake protein HemP SWALL:HEMP_YEREN (SWALL:P31516) (81 aa) fasta scores: E(): 1.3e-31, 100 38d in 81 aa. Also similar to Salmonella typhimurium, and Salmonella typhi putative cytoplasmic protein YdiE or stm1346 or sty1764 SWALL:Q8XGW6 (EMBL:AE008758) (63 aa) fasta scores: E(): 0.019, 41.27 38d in 63 aa | COG4256(5) | | | |
| 5321 |
|
| putative membrane protein|Enterobacterial putative membrane protein (DUF943). This family consists of several hypothetical putative membrane proteins from Escherichia coli, Yersinia pestis and Salmonella typhi; pfam06092 | | PF06092(6) | | |
| 5327 |
|
| putative integral membrane protein|highly similar to Yersinia pestis CO92 YPO1673 and Yersinia pestis KIM y1835. Contains Acriflavin resistance protein (Interpro|IPR001036) | COG5373(6) | | | |
| 5360 |
|
| hypothetical protein|highly similar to Yersinia pestis CO92 YPO2200 and Yersinia pestis KIM y2043, | | | | |
| 5361 |
|
| putative dehydrogenase|Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) [Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only]; COG1028|highly similar to Yersinia pestis CO92 YPO1993 and Yersinia pestis KIM y2317. Contains Short-chain dehydrogenase/reductase SDR (Interpro|IPR002198, (GO:0008152), (GO:0016491)). Contains Glucose/ribitol dehydrogenase (Interpro|IPR002347, (GO:0008152), (GO:0016491)) | COG1028(6)|COG4221(6) | | | |
| 5362 |
|
| putative transposase|Transposase and inactivated derivatives [DNA replication, recombination, and repair]; COG2801|Integrase core domain. Integrase mediates integration of a DNA copy of the viral genome into the host chromosome. Integrase is composed of three domains. The amino-terminal domain is a zinc binding domain pfam02022; pfam00665 | COG2801(7) | PF00665(7) | | |
| 5363 |
|
| putative mannosyltransferase|highly similar to Yersinia pestis CO92 wbyJ and Yersinia pestis KIM y1076., | | | | |
| 5364 |
|
| putative exported protein|Protoporphyrinogen oxidase [Coenzyme metabolism]; COG1232|hypothetical protein; PRK07208|highly similar to Yersinia pestis CO92 wbyH and Yersinia pestis KIM y1072. Contains Adrenodoxin reductase (Interpro|IPR000759, (GO:0006118)) | COG1232(6) | | | |
| 5365 |
|
| hypothetical protein|highly similar to Yersinia pestis CO92 YPO3174 and Yersinia pestis KIM y1011, | | | | |
| 5366 |
|
| putative membrane protein|highly similar to Yersinia pestis CO92 YPO3487 and Yersinia pestis KIM y0697,,, | | | | |
| 5367 |
|
| hypothetical protein|highly similar to Yersinia pestis KIM y0402,,, | | | | |
| 5368 |
|
| hypothetical protein|highly similar to Yersinia pestis CO92 YPO0338,, | | | | |
| 5369 |
|
| hypothetical protein|highly similar to Yersinia pestis CO92 YPO0423 and Yersinia pestis KIM y3758., | | | | |
| 5370 |
|
| Uncharacterized low-complexity proteins|Pentapeptide repeats containing protein [Function unknown]; COG1357|Pentapeptide repeats (8 copies). These repeats are found in many cyanobacterial proteins. The repeats were first identified in hglK. The function of these repeats is unknown. The structure of this repeat has been predicted to be a beta-helix; pfam00805|highly similar to Yersinia pestis CO92 YPO0510 and Yersinia pestis KIM y3664. Contains Pentapeptide repeat (Interpro|IPR001646) | COG1357(6) | PF00805(6) | | |
| 5371 |
|
| hypothetical protein|highly similar to Yersinia pestis CO92 YPO0511a and Yersinia pestis KIM y3662,,, | | | | |
| 5372 |
|
| conserved hypothetical protein|Bacterial protein of unknown function (DUF876). This family consists of a series of hypothetical bacterial sequences of unknown function; pfam05936|highly similar to Yersinia pestis CO92 YPO0513 and Yersinia pestis KIM y3660. | | PF05936(6) | | |
| 5373 |
|
| conserved hypothetical protein|Type VI protein secretion system component VasK [Intracellular trafficking, secretion, and vesicular transport]; COG3523|Ras-like GTPase superfamily. The Ras-like superfamily of small GTPases consists of several families with an extremely high degree of structural and functional similarity; cd00882|ImcF-related; pfam06761|Protein of unknown function (DUF1215). This family represents a conserved region situated towards the C-terminal end of several hypothetical bacterial proteins of unknown function; pfam06744|highly similar to Yersinia pestis KIM y3658. Contains ATP/GTP-binding site motif A (P-loop) (Interpro|IPR001687, (GO:0005524)). Contains ATP-dependent serine protease, Lon family (Interpro|IPR001984, (GO:0006508)) | COG3523(6) | PF06761(6)|PF06744(6) | | |
| 5374 |
|
| putative sugar ABC transporter, permeaseprotein|Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components [Carbohydrate transport and metabolism]; COG1172|highly similar to Yersinia pestis CO92 YPO3332 and Yersinia pestis KIM y0857. Contains ATP/GTP-binding site motif A (P-loop) (Interpro|IPR001687, (GO:0005524)). Contains Bacterial inner-membrane translocator (Interpro|IPR001851, (GO:0016020)). Contains Sodium:dicarboxylate symporter (Interpro|IPR001991, (GO:0016020)) | COG1172(6) | | | |
| 5375 |
|
| putative LysR-family transcriptional regulatory protein|Transcriptional regulator [Transcription]; COG0583|Bacterial regulatory helix-turn-helix protein, lysR family; pfam00126|highly similar to Yersinia pestis CO92 YPO3228 and Yersinia pestis KIM y0961. Contains Bacterial regulatory protein LysR, HTH motif (Interpro|IPR000847, (GO:0006355)) | COG0583(6) | PF00126(6) | | |
| 5376 |
|
| putative beta-glucosidase|Beta-glucosidase-related glycosidases [Carbohydrate transport and metabolism]; COG1472|Glycosyl hydrolase family 3 C terminal domain. This domain is involved in catalysis and may be involved in binding beta-glucan. This domain is found associated with pfam00933; pfam01915|highly similar to Yersinia pestis CO92 bglB and Yersinia pestis KIM y1128. Contains Glycoside hydrolase, family 3, N-terminal (Interpro|IPR001764, (GO:0005975)). Contains Glycoside hydrolase, family 3, C-terminal (Interpro|IPR002772, (GO:0005975)) | COG1472(6) | PF01915(6) | | |
| 5377 |
|
| putative membrane protein|highly similar to Yersinia pestis CO92 YPO2801 and Yersinia pestis KIM y1130,,, | COG4984(6) | | | |
| 5378 |
|
| hypothetical protein|highly similar to Yersinia pestis CO92 YPO2788 and Yersinia pestis KIM y1139,,, | | | | |
| 5379 |
|
| conserved hypothetical protein|highly similar to Yersinia pestis CO92 YPO1174 and Yersinia pestis KIM y3016 | COG3595(6) | | | |
| 5380 |
|
| hypothetical protein|highly similar to Yersinia pestis KIM y2986. | | | | |
| 5381 |
|
| hypothetical protein|highly similar to Yersinia pestis CO92 YPO1255 and Yersinia pestis KIM y2931.,,, | | | | |
| 5382 |
|
| putative periplasmic binding protein|ABC-type Fe3+-hydroxamate transport system, periplasmic component [Inorganic ion transport and metabolism]; COG0614|Periplasmic binding protein TroA_f. These proteins are predicted to function as initial receptors in the ABC metal ion uptake in eubacteria and archaea; cd01139 | COG0614(6) | | | |
| 5383 |
|
| putative oxidoreductase|Uncharacterized protein conserved in bacteria [Function unknown]; COG3146|FAD/FMN-containing dehydrogenases [Energy production and conversion]; COG0277|FAD binding domain. This family consists of various enzymes that use FAD as a co-factor, most of the enzymes are similar to oxygen oxidoreductase; pfam01565|highly similar to Yersinia pestis KIM y2718. Contains WW/Rsp5/WWP domain (Interpro|IPR001202). Contains Oxygen oxidoreductase covalent FAD-binding site (Interpro|IPR006093, (GO:0008246)). Contains FAD linked oxidase, N-terminal (Interpro|IPR006094, (GO:0008246)) | COG3146(6)|COG0277(6) | PF01565(6) | | |
| 5384 |
|
| putative myristoyl-acyl carrier dehydratase|FabZ is a 17kD beta-hydroxyacyl-acyl carrier protein (ACP) dehydratase that primarily catalyzes the dehydration of beta-hydroxyacyl-ACP to trans-2-acyl-ACP, the third step in the elongation phase of the bacterial/ plastid, type II, fatty-acid biosynthesis; cd01288|highly similar to Yersinia pestis KIM fabZ. Contains Thioesterase superfamily (Interpro|IPR006683, (GO:0003824)). Contains Thioesterase superfamily (Interpro|IPR006683, (GO:0003824)) | | | | |
| 5385 |
|
| putative siderophore biosynthetic enzyme|Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis]; COG1670|highly similar to Yersinia pestis CO92 alcB and Yersinia pestis KIM ysuH. | COG1670(6) | | | |
| 5386 |
|
| putative oxidoreductase|short chain dehydrogenase; PRK08324|Class II Aldolase and Adducin N-terminal domain. This family includes class II aldolases and adducins which have not been ascribed any enzymatic function; pfam00596|3-ketoacyl-(acyl-carrier-protein) reductase; PRK07479|highly similar to Yersinia pestis CO92 YPO1811 and Yersinia pestis KIM y2497. Contains DNA gyrase, subunit B (Interpro|IPR000565, (GO:0006265)). Contains Basic helix-loop-helix dimerization domain bHLH (Interpro|IPR001092). Contains Short-chain dehydrogenase/reductase SDR (Interpro|IPR002198, (GO:0008152), (GO:0016491)). Contains Glucose/ribitol dehydrogenase (Interpro|IPR002347, (GO:0008152), (GO:0016491)) | | PF00596(6) | | |
| 5387 |
|
| putative sugar transport system permease protein|Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components [Carbohydrate transport and metabolism]; COG1172|highly similar to Yersinia pestis CO92 YPO1812 and Yersinia pestis KIM y2495. Contains Bacterial inner-membrane translocator (Interpro|IPR001851, (GO:0016020)) | COG1172(6) | | | |
| 5388 |
|
| putative sugar-binding periplasmic protein|ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; COG1879|highly similar to Yersinia pestis CO92 YPO1813 and Yersinia pestis KIM y2494. Contains Periplasmic binding protein/LacI transcriptional regulator (Interpro|IPR001761) | COG1879(6)|COG4213(6) | | | |
| 5389 |
|
| putative permease of ABC transporter|Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components [Carbohydrate transport and metabolism]; COG1172|highly similar to Yersinia pestis KIM y2492. Contains Tetracycline resistance protein TetB (Interpro|IPR001411, (GO:0016021)). Contains Bacterial inner-membrane translocator (Interpro|IPR001851, (GO:0016020)) | COG1172(6) | | | |
| 5390 |
|
| putative membrane protein|highly similar to Yersinia pestis CO92 YPO1852 and Yersinia pestis KIM y2454 | | | | |
| 5391 |
|
| hypothetical protein|highly similar to Yersinia pestis CO92 YPO1877 and Yersinia pestis KIM y2433,,, | | | | |
| 5392 |
|
| putative lipoprotein|highly similar to Yersinia pestis CO92 YPO1930 and Yersinia pestis KIM y2381,, | | | | |
| 5393 |
|
| hypothetical protein|highly similar to Yersinia pestis CO92 YPO1931 and Yersinia pestis KIM y2380,, | | | | |
| 5394 |
|
| putative LysR-family transcriptional regulatory protein|Transcriptional regulator [Transcription]; COG0583|Bacterial regulatory helix-turn-helix protein, lysR family; pfam00126|LysR substrate binding domain. The structure of this domain is known and is similar to the periplasmic binding proteins; pfam03466 | COG0583(4) | PF00126(4)|PF03466(4) | | |
| 5395 |
|
| putative oxidoreductase|Na(+)-translocating NADH-quinone reductase subunit E; PRK12456|highly similar to Yersinia pestis KIM y2376. Contains RnfA-Nqr electron transport subunit (Interpro|IPR003667, (GO:0016020)) | | | | |
| 5396 |
|
| putative dehydrogenase|Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; COG0451|3-beta hydroxysteroid dehydrogenase/isomerase family; pfam01073 | COG0451(5) | PF01073(5) | | |
| 5397 |
|
| Nucleoside-diphosphate-sugar epimerases|NAD dependent epimerase/dehydratase family. This family of proteins utilise NAD as a cofactor. The proteins in this family use nucleotide-sugar substrates for a variety of chemical reactions; pfam01370|3-beta hydroxysteroid dehydrogenase/isomerase family; pfam01073|Best Blastp hit = gi|16122225|ref|NP_405538.1| (NC_003143) putative glycosyl transferase [Yersinia pestis] , gi|15979996|emb|CAC90796.1| (AJ414150) putative glycosyl transferase [Yersinia pestis],(len:384 aa), | | PF01370(1)|PF01073(1) | | |
| 5398 |
|
| putative glycosyl transferase|Glycosyltransferase family 28 N-terminal domain. The glycosyltransferase family 28 includes monogalactosyldiacylglycerol synthase (EC 2.4.1.46) and UDP-N-acetylglucosamine transferase (EC 2.4.1.-); pfam03033 | | PF03033(5)|PF04101(5) | | |
| 5399 |
|
| hypothetical protein | | | | |
| 5400 |
|
| putative membrane protein|highly similar to Yersinia pestis CO92 YPO2004 and Yersinia pestis KIM y2304 | | | | |
| 5401 |
|
| hypothetical protein|highly similar to Yersinia pestis KIM y2303 | | | | |
| 5402 |
|
| Glycerophosphoryl diester phosphodiesterase|highly similar to Yersinia pestis CO92 YPO2035 and Yersinia pestis KIM y2277. Contains Glycerophosphoryl diester phosphodiesterase (Interpro|IPR004129, (GO:0006071), (GO:0008889)) | COG0584(6) | | | |
| 5403 |
|
| putative transcriptional regulatory protein|Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; COG1940|ROK family; pfam00480|highly similar to Yersinia pestis CO92 YPO2036 and Yersinia pestis KIM y2276. Contains ROK family (Interpro|IPR000600) | COG1940(6) | PF00480(6) | | |
| 5404 |
|
| conserved hypothetical phage protein|highly similar to Yersinia pestis CO92 YPO2137 and Yersinia pestis KIM y2183, | | | | |
| 5405 |
|
| putative transport system permease|ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism]; COG0600|highly similar to Yersinia pestis CO92 YPO2287 and Yersinia pestis KIM y2117. Contains Binding-protein-dependent transport systems inner membrane component (Interpro|IPR000515, (GO:0016020)) | COG0600(6) | | | |
| 5406 |
|
| hypothetical protein|highly similar to Yersinia pestis CO92 YPO1620 and Yersinia pestis KIM y1780,,, | | | | |
| 5407 |
|
| hypothetical protein|highly similar to Yersinia pestis CO92 YPO1619 and Yersinia pestis KIM y1779, | | | | |
| 5408 |
|
| putative solute-binding protein|ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; COG1653|Bacterial extracellular solute-binding protein. This family also includes the bacterial extracellular solute-binding protein family POTD/POTF; pfam01547 | COG1653(6) | PF01547(6) | | |
| 5409 |
|
| hypothetical protein|highly similar to Yersinia pestis CO92 YPO2503,, | | | | |
| 5410 |
|
| hypothetical protein|highly similar to Yersinia pestis CO92 YPO2504 and Yersinia pestis KIM y1684,, | | | | |
| 5411 |
|
| putative membrane protein | | | | |
| 5412 |
|
| putative two-component sensor histidine kinase|His Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via trans-autophosphorylat; cd00082|Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; cd00075|highly similar to Yersinia pestis CO92 YPO3008 and Yersinia pestis KIM y1473. Contains ATP-binding region, ATPase-like (Interpro|IPR003594, (GO:0005524)). Contains Histidine kinase A, N-terminal (Interpro|IPR003661, (GO:0016020)). Contains Bacterial sensor protein, C-terminal (Interpro|IPR004358, (GO:0007165)). Contains Histidine kinase (Interpro|IPR005467, (GO:0007165), (GO:0016301)) | COG3920(6) | | | |
| 5413 |
|
| putative phosphate transport system permease|ABC-type uncharacterized transport system, permease component [General function prediction only]; COG4590 | COG4590(6) | | | |
| 5414 |
|
| Hemolysin-coregulated protein (uncharacterized)|Type VI protein secretion system component Hcp (secreted cytotoxin) [Intracellular trafficking, secretion, and vesicular transport]; COG3157|highly similar to Yersinia pestis CO92 YPO2868 and Yersinia pestis KIM y1365 | COG3157(5) | | | |
| 5415 |
|
| hypothetical protein|highly similar to Yersinia pestis CO92 YPO1076 and Yersinia pestis KIM y3100., | | | | |
| 5416 |
|
| hypothetical protein|highly similar to Yersinia pestis CO92 YPO0820 and Yersinia pestis KIM y3208,,, | | | | |
| 5417 |
|
| putative exported protein|highly similar to Yersinia pestis CO92 YPO0862 and Yersinia pestis KIM y3246, | | | | |
| 5418 |
|
| hypothetical protein,, | | | | |
| 5419 |
|
| hypothetical protein|Phage-related protein [Function unknown]; COG4679 | COG4679(5) | | | |
| 5420 |
|
| putative flagellar regulatory protein|highly similar to Yersinia pestis CO92 YPO0720 and Yersinia pestis KIM y3458, | | | | |
| 5421 |
|
| Fimbrial protein|highly similar to Yersinia pestis CO92 YPO0700 and Yersinia pestis KIM y3478. Contains Fimbrial protein (Interpro|IPR000259, (GO:0009289)), | | PF00419(6) | | |
| 5422 |
|
| putative membrane protein|Na+/H+ antiporter [Energy production and conversion]; COG1757|Na+/H+ antiporter family. This family includes integral membrane proteins, some of which are NA+/H+ antiporters; pfam03553|highly similar to Yersinia pestis CO92 YPO0624 and Yersinia pestis KIM y3554. Contains Sodium:dicarboxylate symporter (Interpro|IPR001991, (GO:0016020)) | COG1757(5) | PF03553(6) | | |
| 5423 |
|
| putative exported protein|highly similar to Yersinia pestis CO92 YPO0607, | | | | |
| 5424 |
|
| putative deoxyribose-phosphate aldolase|2-deoxyribose-5-phosphate aldolase (DERA) of the DeoC family. DERA belongs to the class I aldolases and catalyzes a reversible aldol reaction between acetaldehyde and glyceraldehyde 3-phosphate to generate 2-deoxyribose 5-phosphate; cd00959|highly similar to Yersinia pestis CO92 YPO3622 and Yersinia pestis KIM y0247. Contains Deoxyribose-phosphate aldolase (Interpro|IPR002915, (GO:0016228)) | | | | |
| 5425 |
|
| probable carbohydrate kinase|Ribokinase catalyses the phosphorylation of ribose to ribose-5-phosphate using ATP. This reaction is the first step in the ribose metabolism; cd01174|highly similar to Yersinia pestis CO92 YPO3621 and Yersinia pestis KIM y0248. Contains Ribokinase (Interpro|IPR002139, (GO:0006014)). Contains Carbohydrate kinase, PfkB (Interpro|IPR002173). Contains Zinc-containing alcohol dehydrogenase (Interpro|IPR002328, (GO:0008270)) | | | | |
| 5426 |
|
| putative carbohydrate transport protein|ABC-type ribose transport system, auxiliary component [Carbohydrate transport and metabolism]; COG1869|highly similar to Yersinia pestis CO92 YPO3620 and Yersinia pestis KIM y0249 | COG1869(6) | | | |
| 5427 |
|
| putative araC-family transcriptional regulatory protein|AraC-like ligand binding domain. This family represents the arabinose-binding and dimerisation domain of the bacterial gene regulatory protein AraC. The domain is found in conjunction with the helix-turn-helix (HTH) DNA-binding motif pfam00165; pfam02311|AraC-type DNA-binding domain-containing proteins [Transcription]; COG2207|Bacterial regulatory helix-turn-helix proteins, AraC family; pfam00165|highly similar to Yersinia pestis CO92 YPO3619 and Yersinia pestis KIM y0250. Contains Helix-turn-helix, AraC type (Interpro|IPR000005, (GO:0006355)) | COG2207(6) | PF02311(6)|PF00165(6) | | |
| 5428 |
|
| putative oxidoreductase|Predicted dehydrogenases and related proteins [General function prediction only]; COG0673|Oxidoreductase family, NAD-binding Rossmann fold. This family of enzymes utilise NADP or NAD. This family is called the GFO/IDH/MOCA family in swiss-prot; pfam01408|highly similar to Yersinia pestis CO92 YPO3618 and Yersinia pestis KIM y0251. Contains Oxidoreductase, N-terminal (Interpro|IPR000683, (GO:0008152), (GO:0016491)) | COG0673(5) | PF01408(6) | | |
| 5429 |
|
| hypothetical protein|Sugar phosphate isomerases/epimerases [Carbohydrate transport and metabolism]; COG1082|AP endonuclease family 2; These endonucleases play a role in DNA repair; cd00019|highly similar to Yersinia pestis CO92 YPO3617 and Yersinia pestis KIM y0252 | COG1082(6) | | | |
| 5430 |
|
| hypothetical protein|Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains [Signal transduction mechanisms]; COG2204|highly similar to Yersinia pestis CO92 YPO3600 and Yersinia pestis KIM y0274. Contains Helix-turn-helix, Fis-type (Interpro|IPR002197, (GO:0006355)) | COG2204(6) | | | |
| 5431 |
|
| hypothetical protein|highly similar to Yersinia pestis KIM y0035,,, | | | | |
| 5432 |
|
| putative membrane protein|Enterobacterial putative membrane protein (DUF943). This family consists of several hypothetical putative membrane proteins from Escherichia coli, Yersinia pestis and Salmonella typhi; pfam06092 | | PF06092(5) | | |
| 5433 |
|
| hypothetical protein,, | | | | |
| 5434 |
|
| conserved hypothetical protein|highly similar to Yersinia pestis CO92 YPO3983 and Yersinia pestis KIM y3846 | | | | |
| 5435 |
|
| putative phosphoribosyl transferase protein|Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins [Nucleotide transport and metabolism]; COG0503 | COG0503(5) | | | |
| 5436 |
|
| putative membrane protein|highly similar to Yersinia pestis CO92 YPO4081 and Yersinia pestis KIM y4098. Contains Polycystic kidney disease type 2 protein (Interpro|IPR003915, (GO:0016020)), | | | | |
| 5437 |
|
| putative sugar transferase|ADP-heptose:LPS heptosyltransferase [Cell envelope biogenesis, outer membrane]; COG0859|lipopolysaccharide core biosynthesis protein; PRK10422 | COG0859(5) | | | |
| 5438 |
|
| conserved hypothetical protein|DNA-binding winged-HTH domains [Transcription]; COG3710 | COG3710(7) | | | |
| 5439 |
|
| conserved hypothetical protein | | | | |
| 5440 |
|
| putative phage tail protein, | | PF08400(1)|PF07484(1) | | |
| 5441 |
|
| conserved hypothetical protein | | | | |
| 5442 |
|
| conserved hypothetical protein | COG4702(5) | | | |
| 5443 |
|
| conserved hypothetical protein|YcfA-like protein. The viral, archaeal and bacterial proteins making up this family are similar to the YcfA protein expressed by E. coli. Most of these proteins are hypothetical proteins of unknown function; pfam07927|Similar to Rhizobium meliloti hypothetical protein R02039 or Smc04441 SWALL:Q92K60 (EMBL:AL591789) (62 aa) fasta scores: E(): 0.00019, 36.92 38d in 65 aa | | PF07927(5) | | |
| 5444 |
|
| putative hydrolase|Dienelactone hydrolase and related enzymes [Secondary metabolites biosynthesis, transport, and catabolism]; COG0412 | COG0412(5) | | | |
| 5452 |
|
| hypothetical phage protein|Similar to several including: Yersinia pestis hypothetical protein Y1020 or Ypmt1.32 SWALL:O68750 (EMBL:AF074611) (140 aa) fasta scores: E(): 4e-22, 49.63 id in 135 aa and to Salmonella typhi putative lipoprotein Hcm2.0080 SWALL:Q934Y7 (EMBL:AL513384) (140 aa) fasta scores: E(): 4.7e-22, 49.63 38d in 135 aa | | | | |
| 5470 |
|
| putative glycoside hydrolase|Beta-galactosidase [Carbohydrate transport and metabolism]; COG1874|Beta-galactosidase. This group of beta-galactosidase enzymes belong to the glycosyl hydrolase 42 family. The enzyme catalyses the hydrolysis of terminal, non-reducing terminal beta-D-galactosidase residues; pfam02449|A4 beta-galactosidase middle domain: a type 1 glutamine amidotransferase (GATase1)-like domain. This group includes proteins similar to beta-galactosidase from Thermus thermophilus; cd03143 | COG1874(7) | PF02449(7)|PF08533(7) | | |
| 5589 |
|
| putative exported protein|Uncharacterized protein conserved in bacteria, putative lipoprotein [Function unknown]; COG4461|highly similar to Yersinia pestis CO92 YPO0702 and Yersinia pestis KIM y3476 | COG4461(5) | | | |
| 5602 |
|
| hypothetical protein|highly similar to Yersinia pestis CO92 YPO2284 and Yersinia pestis KIM y2114. | | | | |
| 5611 |
|
| putative membrane protein,, | | | | |
| 5613 |
|
| putative transcriptional regulatory protein|Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; cd00093|highly similar to Yersinia pestis CO92 YPO3612 and Yersinia pestis KIM y0260. Contains Helix-turn-helix motif (Interpro|IPR001387, (GO:0003677)) | | | | |
| 5614 |
|
| conserved hypothetical protein|highly similar to Yersinia pestis CO92 YPO3614 and Yersinia pestis KIM y0256 | COG5435(6) | | | |
| 5615 |
|
| pyridoxal-phosphate dependent protein|Cysteine synthase [Amino acid transport and metabolism]; COG0031|Pyridoxal-phosphate dependent enzyme. Members of this family are all pyridoxal-phosphate dependent enzymes. This family includes: serine dehydratase EC:4.2.1.13 P20132, threonine dehydratase EC:4.2.1.16, tryptophan synthase beta chain EC:4.2.1; pfam00291 | COG0031(5) | PF00291(5) | | |
| 5616 |
|
| hypothetical protein|highly similar to Yersinia pestis CO92 YPO0641 and Yersinia pestis KIM y3541.,,, | | | | |
| 5617 |
|
| hypothetical protein|highly similar to Yersinia pestis KIM y3542,,, | | | | |
| 5618 |
|
| hypothetical protein|highly similar to Yersinia pestis CO92 YPO0571 and Yersinia pestis KIM y3608. | | | | |
| 5619 |
|
| putative membrane protein|highly similar to Yersinia pestis CO92 YPO2453 and Yersinia pestis KIM y1737. | | | | |
| 5620 |
|
| putative esterase|Esterase/lipase [Lipid metabolism]; COG0657|highly similar to Yersinia pestis CO92 YPO2007 and Yersinia pestis KIM y2301. Contains Esterase/lipase/thioesterase, active site (Interpro|IPR000379, (GO:0003824)),, | COG0657(5) | | | |
| 5621 |
|
| putative sugar transporter|putative sialic acid transporter; PRK03893|Major Facilitator Superfamily; pfam07690|highly similar to Yersinia pestis CO92 YPO1932 and Yersinia pestis KIM y2379. Contains General substrate transporter (Interpro|IPR005828, (GO:0016020)). Contains Sugar transporter superfamily (Interpro|IPR005829, (GO:0016020)). Contains Major facilitator superfamily (MFS) (Interpro|IPR007114) | | PF07690(4) | | |
| 5622 |
|
| conserved hypothetical protein|highly similar to Yersinia pestis CO92 YPO1874 and Yersinia pestis KIM y2435., | | | | |
| 5623 |
|
| hypothetical protein|highly similar to Yersinia pestis CO92 YPO1879 and Yersinia pestis KIM y2432.,,, | | | | |
| 5624 |
|
| hypothetical protein|highly similar to Yersinia pestis CO92 YPO2591 and Yersinia pestis KIM y1161,,, | | | | |
| 5625 |
|
| hypothetical protein|highly similar to Yersinia pestis KIM y2929,, | | | | |
| 5626 |
|
| hypothetical protein|highly similar to Yersinia pestis CO92 YPO4106 and Yersinia pestis KIM y4120,,, | | | | |
| 5627 |
|
| Transcriptional regulators|DNA-binding transcriptional repressor of ribose metabolism; PRK10423|highly similar to Yersinia pestis KIM y0009 | | | | |
| 5628 |
|
| hypothetical protein|highly similar to Yersinia pestis CO92 YPO3890,, | | | | |
| 5629 |
|
| hypothetical protein|highly similar to Yersinia pestis CO92 YPO0335 and Yersinia pestis KIM y0594,,, | | | | |
| 5630 |
|
| hypothetical protein | | | | |
| 5631 |
|
| putative membrane protein|Integral membrane protein DUF6. This family includes many hypothetical membrane proteins of unknown function. Many of the proteins contain two copies of the aligned region; pfam00892|highly similar to Yersinia pestis CO92 YPO1170. Contains Eukaryotic thiol (cysteine) protease (Interpro|IPR000169, (GO:0006508)). Contains Protein of unknown function DUF6 (Interpro|IPR000620) | | PF00892(5) | | |
| 5632 |
|
| hypothetical protein|highly similar to Yersinia pestis KIM y3014, | | | | |
| 5633 |
|
| putative acyl carrier protein|highly similar to Yersinia pestis CO92 YPO1462. Contains Phosphopantetheine-binding domain (Interpro|IPR006163) | | | | |
| 5634 |
|
| conserved hypothetical protein|Protein of unknown function (DUF497); pfam04365|highly similar to Yersinia pestis KIM y2428 | | PF04365(5) | | |
| 5635 |
|
| hypothetical protein|highly similar to Yersinia pestis KIM y2031, | | | | |
| 5636 |
|
| ABC-type nitrate/sulfonate/taurine/bicarbonate transport systems, periplasmic components|alkanesulfonate transporter substrate-binding subunit; PRK11553|highly similar to Yersinia pestis CO92 YPO2286 and Yersinia pestis KIM y2116. Contains Solute-binding protein/glutamate receptor (Interpro|IPR001311, (GO:0006810)) | COG0715(5) | | | |
| 5637 |
|
| putative alanine racemase|Alanine racemase. This CD corresponds to alanine racemases, the prototype of the alanine racemase superfamily; cd00430 | | | | |
| 5638 |
|
| hypothetical protein|Uncharacterized conserved protein [Function unknown]; COG4104|highly similar to Yersinia pestis KIM y1557,,, | COG4104(4) | | | |
| 5639 |
|
| putative membrane protein|Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations; cd00116|highly similar to Yersinia pestis KIM y1460. Contains Leucine-rich repeat (Interpro|IPR001611), | COG4886(1) | | | |
| 5640 |
|
| putative membrane protein|highly similar to Yersinia pestis CO92 YPO2906 and Yersinia pestis KIM y1323,, | | | | |
| 5641 |
|
| hypothetical protein|no significant database match found | | | | |
| 5642 |
|
| putative exported protein|Uncharacterized protein conserved in bacteria, putative lipoprotein [Function unknown]; COG4461|highly similar to Yersinia pestis CO92 YPO2684 and Yersinia pestis KIM y1256. | COG4461(6) | | | |
| 5643 |
|
| hypothetical protein|Uncharacterized protein conserved in bacteria [Function unknown]; COG3122|highly similar to Yersinia pestis KIM y3179., | COG3122(4) | | | |
| 5644 |
|
| General secretory pathway proteins G and H and related periplasmic/secreted proteins|Type II secretory pathway, pseudopilin PulG [Cell motility and secretion / Intracellular trafficking and secretion]; COG2165|highly similar to Yersinia pestis KIM y3200. Contains Cytochrome c heme-binding site (Interpro|IPR000345, (GO:0006118)). Contains Bacterial general secretion pathway protein H (Interpro|IPR002416, (GO:0015628)) | COG2165(6) | | | |
| 5645 |
|
| putative transcription repressor|helix_turn _helix lactose operon repressor; smart00354|Transcriptional regulators [Transcription]; COG1609 | COG1609(6) | | SM00354(6) | |
| 5646 |
|
| Di- and tricarboxylate transporters|Permease SLC13 (solute carrier 13). The sodium/dicarboxylate cotransporter NaDC-1 has been shown to translocate Krebs cycle intermediates such as succinate, citrate, and alpha-ketoglutarate across plasma membranes rabbit, human, and rat kidney; cd01115|highly similar to Yersinia pestis KIM y3435. Contains H+-transporting two-sector ATPase, A subunit (Interpro|IPR000568, (GO:0016020)). Contains Sodium/sulphate symporter (Interpro|IPR001898, (GO:0016020)) | COG0471(6) | | | |
| 5647 |
|
| hypothetical protein|highly similar to Yersinia pestis CO92 YPO0761 and Yersinia pestis KIM y3433,,, | | | | |
| 5648 |
|
| hypothetical protein|highly similar to Yersinia pestis CO92 YPO0763 and Yersinia pestis KIM y3431.,,, | | | | |
| 5649 |
|
| hypothetical protein|highly similar to Yersinia pestis CO92 YPO0768 and Yersinia pestis KIM y3425, | | | | |
| 5650 |
|
| putative exported protein|highly similar to Yersinia pestis CO92 YPO0769 and Yersinia pestis KIM y3424, | | | | |
| 5651 |
|
| ATP-binding protein|ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; COG1132|ABC transporter transmembrane region. This family represents a unit of six transmembrane helices. Many members of the ABC transporter family (pfam00005) have two such regions; pfam00664|MsbA is an essential ABC transporter, closely related to eukaryotic MDR proteins; cd03251|The pleiotropic drug resistance-like (PDR) family of ATP-binding cassette (ABC) transporters. PDR is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes; cd03232 | COG1132(6) | PF00664(6) | | |
| 5652 |
|
| putative membrane protein|muropeptide transporter; PRK11010|Sugar phosphate permease [Carbohydrate transport and metabolism]; COG2271|highly similar to Yersinia pestis CO92 YPO0772 and Yersinia pestis KIM y3421. Contains Cl- channel, voltage gated (Interpro|IPR001807, (GO:0016020)) | COG2271(6) | | | |
| 5653 |
|
| putative thioesterase|Predicted thioesterase involved in non-ribosomal peptide biosynthesis [Secondary metabolites biosynthesis, transport, and catabolism]; COG3208|highly similar to Yersinia pestis CO92 YPO0773 and Yersinia pestis KIM y3420. Contains Esterase/lipase/thioesterase, active site (Interpro|IPR000379, (GO:0003824)). Contains Thioesterase (Interpro|IPR001031, (GO:0009058), (GO:0016788)) | COG3208(6) | | | |
| 5654 |
|
| conserved hypothetical protein|Oxidoreductase (NAD-binding), involved in siderophore biosynthesis [Secondary metabolites biosynthesis, transport, and catabolism]; COG4693|Oxidoreductase family, NAD-binding Rossmann fold. This family of enzymes utilise NADP or NAD. This family is called the GFO/IDH/MOCA family in swiss-prot; pfam01408|highly similar to Yersinia pestis CO92 YPO0774 and Yersinia pestis KIM y3419 | COG4693(6) | PF01408(6) | | |
| 5655 |
|
| Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)|Saccharopine dehydrogenase. This family comprised of three structural domains that can not be separated in the linear sequence. In some organisms this enzyme is found as a bifunctional polypeptide with lysine ketoglutarate reductase; pfam03435|highly similar to Yersinia pestis CO92 YPO0775 and Yersinia pestis KIM y3418. Contains Glucose/ribitol dehydrogenase (Interpro|IPR002347, (GO:0008152), (GO:0016491)) | | PF03435(6) | | |
| 5656 |
|
| putative TonB-dependent outer membrane receptor|Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; COG1629|TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; cd01347|highly similar to Yersinia pestis CO92 YPO1011. Contains TonB-dependent receptor protein (Interpro|IPR000531, (GO:0016020)) | COG1629(6) | | | |
| 5657 |
|
| putative antigenic leucine-rich repeat protein|Leucine-rich repeat (LRR) protein [Function unknown]; COG4886|highly similar to Yersinia pestis CO92 YPO1006 and Yersinia pestis KIM y3399. Contains Leucine-rich repeat (Interpro|IPR001611) | COG4886(5) | | | |
| 5658 |
|
| enterotoxin-like protein|ShET2 enterotoxin, N-terminal region. The members of this family are are sequences that are similar to the N-terminal half of the ShET2 enterotoxin produced by Shigella flexneri and Escherichia coli; pfam07906, | | PF07906(5) | | |
| 5659 |
|
| conserved hypothetical protein|Uncharacterized protein conserved in bacteria [Function unknown]; COG2964|highly similar to Yersinia pestis CO92 YPO0626. | COG2964(5) | | | |
| 5660 |
|
| hypothetical protein|highly similar to Yersinia pestis CO92 YPO3946 and Yersinia pestis KIM y3882, | | | | |
| 5661 |
|
| hypothetical protein|highly similar to Yersinia pestis CO92 YPO3952 and Yersinia pestis KIM y3877 | | | | |
| 5662 |
|
| putative exported protein|Enterobacterial putative membrane protein (DUF943). This family consists of several hypothetical putative membrane proteins from Escherichia coli, Yersinia pestis and Salmonella typhi; pfam06092|highly similar to Yersinia pestis CO92 YPO3981 and Yersinia pestis KIM y3848. Contains Calcium-binding EF-hand (Interpro|IPR002048, (GO:0005509)) | | PF06092(6) | | |
| 5663 |
|
| putative membrane protein|highly similar to Yersinia pestis CO92 YPO4050 and Yersinia pestis KIM y4070., | | | | |
| 5664 |
|
| putative tight adherance operon protein|Flp pilus assembly protein, secretin CpaC [Intracellular trafficking and secretion]; COG4964|Bacterial type II and III secretion system protein; pfam00263|Similar to Actinobacillus actinomycetemcomitans rough colony protein A rcpA SWALL:Q9X6J1 (EMBL:AF139249) (460 aa) fasta scores: E(): 1e-44, 39.46 38d in 446 aa,and to Pasteurella multocida putative rough colony protein A PM0852 SWALL:Q9CMH4 (EMBL:AE006123) (470 aa) fasta scores: E(): 4.2e-38, 40.73 38d in 437 aa | COG4964(4) | PF00263(5) | | |
| 5665 |
|
| possible reguatory protein|Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment; cd00383|Similar to many proteins including: Yersinia pestis putative regulatory membrane protein Ypo0804 SWALL:Q8ZHT0 (EMBL:AJ414144) (238 aa) fasta scores: E(): 9.2e-35, 50.5 id in 200 aa and to Yersinia pestis KIM hypothetical Y3192 SWALL:AAM86742 (EMBL:AE013920) (234 aa) fasta scores: E(): 1.8e-33, 50 38d in 196 aa | | | | |
| 5666 |
|
| cold shock-like protein CspC2|Cold shock proteins [Transcription]; COG1278|Similar to Escherichia coli, Escherichia coli O157:H7, Salmonella typhimurium, and Salmonella typhi cold shock-like protein CspC cspC or msmB or b1823 or z2868 or ecs2533 or stm1837 or sty1967 SWALL:CSPC_ECOLI (SWALL:P36996) (68 aa) fasta scores: E(): 1.6e-21, 84.84 id in 66 aa, and to Yersinia pestis cold shock protein ypo1655 SWALL:Q8ZFN9 (EMBL:AJ414149) (70 aa) fasta scores: E(): 1.7e-27, 100 38d in 70 aa | COG1278(6) | | | |
| 5667 |
|
| putative chemotaxis protein|two-component sensor protein; PRK09470|c-di-GMP phosphodiesterase class II (HD-GYP domain) [Signal transduction mechanisms]; COG2206|Metal dependent phosphohydrolases with conserved 'HD' motif; cd00077|Similar to Vibrio cholerae chemotactic transducer-related protein Vca0895 SWALL:Q9KL53 (EMBL:AE004417) (981 aa) fasta scores: E(): 2.7e-81,37.07 38d in 990 aa. Similar in the N-terminus to Rhizobium meliloti adenylate cyclase 1 Cya1 or CyaA or r00259 or smc00339 SWALL:CYA1_RHIME (SWALL:P19485) (665 aa) fasta scores: E(): 2.5e-11, 22.62 38d in 411 aa,, | COG2206(2) | PF00672(1) | | |
| 5668 |
|
| conserved hypothetical protein,, | | | | |
| 5669 |
|
| conserved hypothetical protein, | | | | |
| 5670 |
|
| putative membrane protein | | | | |
| 5800 |
|
| putrescine/spermidine ABC transporter ATPase|ABC-type spermidine/putrescine transport systems, ATPase components [Amino acid transport and metabolism]; COG3842|ABC (ATP-binding cassette) transporter nucleotide-binding domain; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The...; cl09099 | COG3842(2) | | | |
| 5801 |
|
| hypothetical protein|Uncharacterized protein conserved in bacteria [Function unknown]; COG4643 | COG4643(6) | PF08273(5) | | |
| 5804 |
|
| Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase|Selenocysteine lyase/Cysteine desulfurase [Posttranslational modification, protein turnover, chaperones]; COG0520 | COG0075(1), COG0075(2)|COG0520(2), COG0520(1)|COG0075(1) | | | |
| 5810 |
|
| putataive phosphotransferase system PTS|PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes; cd00212 | | | | |
| 5988 |
|
| putative flagellar hook-length control protein|Left-Handed Parallel beta-Helix; Alignment contains 4 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X); cd00208 | COG3144(4) | | | |
| 6004 |
|
| hypothetical protein|highly similar to Yersinia pestis CO92 YPO1905 and Yersinia pestis KIM y2406. | | | | |
| 6011 |
|
| putative regulator|Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; cd00093|highly similar to Yersinia pestis CO92 YPO4028 and Yersinia pestis KIM y4049. Contains Helix-turn-helix motif (Interpro|IPR001387, (GO:0003677)) | | | | |
| 6012 |
|
| putative O-unit flippase | | | | |
| 6013 |
|
| hypothetical protein | | | | |
| 6014 |
|
| hypothetical protein|Uncharacterized protein conserved in bacteria [Function unknown]; COG4304 | COG4304(5) | | | |
| 6015 |
|
| | | | | |
| 6016 |
|
| | | | | |
| 6017 |
|
| | | | | |
| 6018 |
|
| | | | | |
| 6019 |
|
| | | | | |
| 6020 |
|
| modification methylase|DNA modification methylase [DNA replication, recombination, and repair]; COG0863|highly similar to Yersinia pestis CO92 YPO0391 and Yersinia pestis KIM y3792. Contains N6 adenine-specific DNA methyltransferase, N12 class (Interpro|IPR002296, (GO:0008170)) | COG0863(5) | | | |
| 6021 |
|
| DNA mismatch repair enzyme (predicted ATPase)|Histidine kinase-like ATPases; Histidine kinase-, DNA gyrase B-, phytochrome-like ATPases; smart00387|highly similar to Yersinia pestis CO92 YPO0392 and Yersinia pestis KIM y3791. Contains ATP-binding region, ATPase-like (Interpro|IPR003594, (GO:0005524)) | | | SM00387(5) | |
| 6022 |
|
| hypothetical protein|highly similar to Yersinia pestis CO92 YPO0393 and Yersinia pestis KIM y3790.,, | | | | |
| 6023 |
|
| ATPase involved in DNA repair|Uncharacterized protein conserved in bacteria [Function unknown]; COG4913|highly similar to Yersinia pestis KIM y3786 | COG4913(5) | | | |
| 6024 |
|
| hypothetical protein|Uncharacterized protein conserved in bacteria [Function unknown]; COG4924|highly similar to Yersinia pestis CO92 YPO0397 and Yersinia pestis KIM y3785. | COG4924(5) | | | |
| 6025 |
|
| hypothetical protein|highly similar to Yersinia pestis KIM y3711. | | | | |
| 6026 |
|
| hypothetical protein|highly similar to Yersinia pestis CO92 YPO4032 and Yersinia pestis KIM y4051.,, | | | | |
| 6027 |
|
| putative membrane protein|Protein of unknown function (DUF1240). This family consists of a number of hypothetical putative membrane proteins which seem to be specific to Yersinia pestis. The function of this family is unknown; pfam06836 | | PF06836(6) | | |
| 6028 |
|
| hypothetical protein|highly similar to Yersinia pestis KIM y1250., | | | | |
| 6029 |
|
| hypothetical protein|highly similar to Yersinia pestis KIM y1656, | | | | |
| 6030 |
|
| conserved hypothetical protein|highly similar to Yersinia pestis CO92 YPO2485 and Yersinia pestis KIM y1702,, | | | | |
| 6031 |
|
| hypothetical protein|highly similar to Yersinia pestis CO92 YPO2261 and Yersinia pestis KIM y2103,, | | | | |
| 6032 |
|
| hypothetical protein|highly similar to Yersinia pestis CO92 YPO2006 and Yersinia pestis KIM y2302.,, | | | | |
| 6033 |
|
| putative DNA-binding protein|Uncharacterized protein conserved in bacteria [Function unknown]; COG2964|highly similar to Yersinia pestis CO92 YPO1671 and Yersinia pestis KIM y1832. | COG2964(5) | | | |
| 6034 |
|
| Putative L-xylulose-5-phosphate 3-epimerase|Xylose isomerase-like TIM barrel. This TIM alpha/beta barrel structure is found in xylose isomerase and in endonuclease IV (EC:3.1.21.2). This domain is also found in the N termini of bacterial myo-inositol catabolism proteins; pfam01261|highly similar to Yersinia pestis CO92 YPO1670 and Yersinia pestis KIM y1831 | | PF01261(5) | | |
| 6035 |
|
| YjgF-family lipoprotein|YjgH belong to a large family of proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase however there is no sequence similarity and no functional connection; cd02198|highly similar to Yersinia pestis CO92 YPO1669 and Yersinia pestis KIM y1830. Contains YjgF-like protein (Interpro|IPR006056). Contains Endoribonuclease L-PSP (Interpro|IPR006175) | | | | |
| 6036 |
|
| hypothetical protein|highly similar to Yersinia pestis KIM y1808., | | | | |
| 6037 |
|
| conserved hypothetical protein|Predicted nuclease of the RNAse H fold, HicB family [General function prediction only]; COG1598|Predicted transcriptional regulators containing the CopG/Arc/MetJ DNA-binding domain and a metal-binding domain [Transcription]; COG0864|highly similar to Yersinia pestis CO92 YPO1817 and Yersinia pestis KIM y2490 | COG1598(5)|COG0864(5) | | | |
| 6038 |
|
| hypothetical protein|highly similar to Yersinia pestis KIM y2437.,,, | | | | |
| 6039 |
|
| hypothetical protein|highly similar to Yersinia pestis CO92 YPO1897 and Yersinia pestis KIM y2412. | | | | |
| 6040 |
|
| ABC-type multidrug/protein/lipid transport system, ATPase component|Uncharacterized protein conserved in bacteria [Function unknown]; COG4253|highly similar to Yersinia pestis CO92 YPO1475 and Yersinia pestis KIM y2695 | COG4253(5) | | | |
| 6041 |
|
| putative exported protein|highly similar to Yersinia pestis CO92 YPO1474 and Yersinia pestis KIM y2696,, | | | | |
| 6042 |
|
| hypothetical protein|highly similar to Yersinia pestis KIM y2815, | | | | |
| 6043 |
|
| putative phage protein|highly similar to Yersinia pestis CO92 YPO1097 and Yersinia pestis KIM y3082,, | | | | |
| 6044 |
|
| hypothetical protein|highly similar to Yersinia pestis KIM y3009 | | | | |
| 6045 |
|
| hypothetical protein|highly similar to Yersinia pestis KIM y1063. | | | | |
| 6046 |
|
| hypothetical protein|highly similar to Yersinia pestis KIM y0930 | | | | |
| 6047 |
|
| hypothetical protein|highly similar to Yersinia pestis KIM y0809. Contains Prenyl group binding site (CAAX box) (Interpro|IPR001230), | | | | |
| 6048 |
|
| putative membrane protein|highly similar to Yersinia pestis CO92 YPO0101 and Yersinia pestis KIM y0289, | | | | |
| 6049 |
|
| colicin|S-type Pyocin. This family represents a conserved region approximately 180 residues long within bacterial S-type pyocins. Pyocins are polypeptide toxins produced by, and active against, bacteria; pfam06958 | | PF06958(4) | | |
| 6050 |
|
| hypothetical protein|highly similar to Yersinia pestis CO92 YPO3885,, | | | | |
| 6051 |
|
| conserved hypothetical protein|Phage-related protein [Function unknown]; COG4679|highly similar to Yersinia pestis CO92 YPO3486 and Yersinia pestis KIM y0698, | COG4679(6) | | | |
| 6052 |
|
| conserved hypothetical protein | | | | |
| 6053 |
|
| hypothetical protein|highly similar to Yersinia pestis KIM y0849,, | | | | |
| 6054 |
|
| Acetyltransferases (the isoleucine patch superfamily)|Left-Handed Parallel beta-Helix; Alignment contains 4 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X); cd00208|similar to Yersinia pestis CO92 YPO2189. | | | | |
| 6055 |
|
| conserved hypothetical protein | | | | |
| 6056 |
|
| hypothetical protein|highly similar to Yersinia pestis CO92 YPO2795,, | | | | |
| 6057 |
|
| hypothetical protein|Protein of unknown function (DUF1240). This family consists of a number of hypothetical putative membrane proteins which seem to be specific to Yersinia pestis. The function of this family is unknown; pfam06836|highly similar to Yersinia pestis KIM y1138 | | PF06836(5) | | |
| 6058 |
|
| conserved hypothetical protein | | | | |
| 6059 |
|
| hypothetical protein|Uncharacterized protein conserved in bacteria [Function unknown]; COG3809 | COG3809(4) | | | |
| 6060 |
|
| conserved hypothetical protein | | | | |
| 6061 |
|
| putative exported protein|highly similar to Yersinia pestis CO92 YPO3065 and Yersinia pestis KIM y1416, | | | | |
| 6062 |
|
| putative membrane protein|Protein of unknown function (DUF1240). This family consists of a number of hypothetical putative membrane proteins which seem to be specific to Yersinia pestis. The function of this family is unknown; pfam06836 | | PF06836(6) | | |
| 6063 |
|
| putative membrane protein|Protein of unknown function (DUF1240). This family consists of a number of hypothetical putative membrane proteins which seem to be specific to Yersinia pestis. The function of this family is unknown; pfam06836 | | PF06836(6) | | |
| 6064 |
|
| hypothetical protein|Cellulase (glycosyl hydrolase family 5); pfam00150|highly similar to Yersinia pestis KIM y3438. Contains Glycoside hydrolase, family 5 (Interpro|IPR001547, (GO:0005975)) | | PF00150(5) | | |
| 6065 |
|
| hypothetical protein | | | | |
| 6066 |
|
| conserved hypothetical protein|Fic protein family. This family consists of the Fic (filamentation induced by cAMP) protein and its relatives; pfam02661 | | PF02661(3) | | |
| 6067 |
|
| putative methyltransferase|Site-specific DNA methylase [DNA replication, recombination, and repair]; COG0338|highly similar to Yersinia pestis CO92 YPO2088 and Yersinia pestis KIM y2224. | COG0338(4) | | | |
| 6068 |
|
| | | | | |
| 6069 |
|
| | | | | |
| 6070 |
|
| | | | | |
| 6071 |
|
| | | | | |
| 6072 |
|
| | | | | |
| 6073 |
|
| | | | | |
| 6074 |
|
| | | | | |
| 6075 |
|
| | | | | |
| 6076 |
|
| | | | | |
| 6077 |
|
| | | | | |
| 6078 |
|
| | | | | |
| 6079 |
|
| | | | | |
| 6080 |
|
| | | | | |
| 6081 |
|
| | | | | |
| 6082 |
|
| | | | | |
| 6083 |
|
| | | | | |
| 6084 |
|
| | | | | |
| 6085 |
|
| | | | | |
| 6086 |
|
| | | | | |
| 6087 |
|
| | | | | |
| 6088 |
|
| | | | | |
| 6089 |
|
| | | | | |
| 6090 |
|
| | | | | |
| 6091 |
|
| | | | | |
| 6092 |
|
| | | | | |
| 6093 |
|
| | | | | |
| 6094 |
|
| | | | | |
| 6095 |
|
| | | | | |
| 6096 |
|
| | | | | |
| 6097 |
|
| | | | | |
| 6098 |
|
| | | | | |
| 6099 |
|
| | | | | |
| 6100 |
|
| | | | | |
| 6101 |
|
| | | | | |
| 6102 |
|
| | | | | |
| 6103 |
|
| hypothetical protein|Similar to Yersinia pestis KIM hypothetical y3270 SWALL:AAM86820 (EMBL:AE013928) (93 aa) fasta scores: E(): 3.3e-33, 81.72 38d in 93 aa | | | | |
| 6104 |
|
| conserved hypothetical protein, | | | | |
| 6105 |
|
| hypothetical protein|EthD protein. This family consists of several bacterial sequences which are related to the EthD protein of Rhodococcus ruber. In Rhodococcus ruber, EthD is thought to be involved in the degradation of ethyl tert-butyl ether (ETBE); pfam07110|Similar to Yersinia pestis hypothetical protein DffD SWALL:Q93AB2 (EMBL:AF426171) (109 aa) fasta scores: E(): 8.8e-35, 78.7 38d in 108 aa, and to Bacillus halodurans hypothetical protein BH0200 SWALL:Q9KGB0 (EMBL:AP001507) (107 aa) fasta scores: E(): 0.53, 27.55 id in 98 aa | | PF07110(4) | | |
| 6106 |
|
| chitobiase precursor|Putative carbohydrate binding domain. This domain represents the N terminal domain in chitobiases and beta-hexosaminidases EC:3.2.1.52; pfam03173|N-acetyl-beta-hexosaminidase [Carbohydrate transport and metabolism]; COG3525|Glycosyl hydrolase family 20, domain 2. This domain has a zincin-like fold; pfam02838|Chitobiase C-terminus domain. Chitobiase (AKA N-acetylglucosaminidase) digests the beta, 1-4 glycosidic bonds of the N-acetylglucosamine (NAG) oligomers found in chitin, an important structural element of fungal cell wall and arthropod exoskeletons; cd02847 | COG3525(2) | PF03173(2)|PF02838(2)|PF00728(2), PF02838(2)|PF00728(2) | | |
| 6107 |
|
| hypothetical phage protein,, | | | | |
| 6108 |
|
| putative phage protein|Bacterial surface proteins containing Ig-like domains [Cell motility and secretion]; COG5492 | COG5492(5) | PF02368(1) | | |
| 6109 |
|
| hypothetical phage protein,, | | | | |
| 6110 |
|
| putative phage protein|Phage tail protein. This family of proteins include phage tail proteins. They probably include bacterial Ig-like domains related to pfam02368. Which also includes a number of phage tail invasin proteins; pfam08813 | | PF08813(5) | | |
| 6111 |
|
| hypothetical phage protein|Domain of unknown function (DUF1789). Putative uncharacterised domain found in phage-related conserved hypothetical protein from Bordetella; pfam08748 | | PF08748(5) | | |
| 6112 |
|
| putative sulfate permease|Sulfate permease and related transporters (MFS superfamily) [Inorganic ion transport and metabolism]; COG0659|Sulfate transporter family. Mutations in the diastrophic dysplasia protein (solute carrier family 26 member 2) lead to several human diseases; pfam00916|STAS domain. The STAS (after Sulphate Transporter and AntiSigma factor antagonist) domain is found in the C terminal region of Sulphate transporters and bacterial antisigma factor antagonists; pfam01740 | COG0659(2) | PF00916(2), PF00916(2)|PF01740(2) | | |
| 6114 |
|
| hypothetical protein|doubtful CDS which is similar in parts to Yersinia pestis hypothetical protein Ypo2189 SWALL:Q8ZEI1 (EMBL:AJ414151) (82 aa) fasta scores: E(): 6.7e-08, 62.5 id in 56 aa, | | | | |
| 6115 |
|
| urease accessory protein|UreD urease accessory protein. UreD is a urease accessory protein. Urease pfam00449 hydrolyses urea into ammonia and carbamic acid; pfam01774 | | PF01774(4) | | P52316(1) |