ClusterHMMLocusDescriptionCOGPfamSmartSwiss-Prot
3841
putative tail fiber protein|Prophage tail fibre N-terminal. This domain is found at the N-terminus of prophage tail fibre proteins; pfam08400PF08400(6)
3907
hypothetical protein|Predicted esterase of the alpha-beta hydrolase superfamily [General function prediction only]; COG1752COG1752(7)PF0028(2)
4222
hypothetical proteinCOG3026(4)
4599
putative phosphotransferase system (PTS), fructose-specific|PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes; cd00211
4608
transcriptional regulator, TetR family|transcriptional regulator BetI; PRK00767|Bacterial regulatory proteins, tetR family; pfam00440PF00440(6)
4923
MarR-family transcriptional regulatory protein|Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; cl00088
4931
hypothetical protein
5275
hypothetical protein YajF (ROK family protein)|Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; COG1940|fructokinase; PRK09557,COG1940(5)
5282
hypothetical membrane protein|Domain of unknown function (DUF477). The function of this presumed domain is unknown. It is found in both eukarya and eubacteria; pfam04536PF04536(5)
5534
conserved hypothetical protein|Protein of unknown function (DUF1524); pfam07510COG1479(5)|COG3586(5)PF07510(5)
5539
capsule export protein KpsC|Capsule polysaccharide export protein [Cell envelope biogenesis, outer membrane]; COG3563COG3563(4)
5541
putative transcriptional antiterminator protein|CAT RNA binding domain. This RNA binding domain is found at the amino terminus of transcriptional antitermination proteins such as BglG, SacY and LicT. These proteins control the expression of sugar metabolising operons in Gram+ and Gram- bacteria; pfam03123COG3711(1)PF03123(3)|PF00874(3), PF00874(1)
5542
putative aminotransferaseCOG1168(3)
5543
hypothetical posphosugar isomerase|Predicted sugar phosphate isomerase involved in capsule formation [Cell envelope biogenesis, outer membrane]; COG0794COG0794(4)
5549
hypothetical protein
5913
invasion protein IbeA,COG0644(1)PF01946(1)
5915
hypothetical protein|Uncharacterized protein conserved in bacteria [Function unknown]; COG3181COG3181(3)
5916
hypothetical isochorismatase family protein YcdL|Cysteine hydrolases; This family contains amidohydrolases, like CSHase (N-carbamoylsarcosine amidohydrolase), involved in creatine metabolism and nicotinamidase, converting nicotinamide to nicotinic acid and ammonia in the pyridine nucleotide cycle; cd00431
5917
hypothetical protein YahE
5918
carbamate kinase-like protein YahI|AAK_CK: Carbamate kinase (CK) catalyzes both the ATP-phosphorylation of carbamate and carbamoyl phosphate (CP) utilization with the production of ATP from ADP and CP; cd04235
5919
hypothetical protein|amidase; PRK08186
5920
putative permease|cytosine permease; PRK11017
5921
transcriptional regulator, LysR family|predicted DNA-binding transcriptional regulator; PRK11074|Bacterial regulatory helix-turn-helix protein, lysR family; pfam00126|LysR substrate binding domain. The structure of this domain is known and is similar to the periplasmic binding proteins; pfam03466PF00126(3)|PF03466(3)
5922
putative transcriptional antiterminator|HTH domain. This family includes helix-turn-helix domains in a wide variety of proteins; pfam08279|Mga helix-turn-helix domain. M regulator protein trans-acting positive regulator (Mga) is a DNA-binding protein that activates the expression of several important virulence genes in group A streptococcus in response to changing environmental conditions; pfam05043|Phosphotransferase system, galactitol-specific IIB component [Carbohydrate transport and metabolism]; COG3414COG3414(3)PF08279(3)|PF05043(3)|PF00874(3)
5923
putative fructose-bisphosphate aldolase class-II|Tagatose-1,6-bisphosphate (TBP) aldolase and related Type B Class II aldolases; cd00947
5925
polysialic acid transport protein KpsM|ABC-type polysaccharide/polyol phosphate export systems, permease component [Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane]; COG1682COG1682(3)
5926
polysialic acid transport ATP-binding protein KpsT|Domain 2 of NFT1 (New full-length MRP-type transporter 1). NFT1 belongs to the MRP (mulrtidrug resisitance-associated protein) family of ABC transporters; cd03369|ABC_KpsT_Wzt The KpsT/Wzt ABC transporter subfamily is involved in extracellular polysaccharide export; cd03220COG4555(1)
5927
capsule polysaccharide export protein KpsS|Capsule polysaccharide export protein [Cell envelope biogenesis, outer membrane]; COG3562|Capsule polysaccharide biosynthesis protein. This family includes export proteins involved in capsule polysaccharide biosynthesis, such as KpsS and LipB; pfam05159COG3562(3)PF05159(3)
5928
3-deoxy-manno-octulosonate cytidylyltransferase|Nucleotidyl transferase. This family includes a wide range of enzymes which transfer nucleotides onto phosphosugars; cl00502
5929
polysialic acid transport protein KpsD precursor|Periplasmic protein involved in polysaccharide export, contains SLBB domain of b-grasp fold [Cell wall/membrane/envelope biogenesis]; COG1596|Polysaccharide biosynthesis/export protein. This is a family of periplasmic proteins involved in polysaccharide biosynthesis and/or export; pfam02563COG1596(2)PF02563(3)
5930
polysialic acid capsule expression protein KpsF|D-arabinose 5-phosphate isomerase; Provisional; PRK10892|KpsF-like protein. KpsF is an arabinose-5-phosphate isomerase which contains SIS (Sugar ISomerase) domains. SIS domains are found in many phosphosugar isomerases and phosphosugar binding proteins. KpsF catalyzes the reversible reaction of ribulose 5...; cd05014|This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with KpsF/GutQ domains in the API [A5P (D-arabinose 5-phosphate) isomerase] protein. These APIs catalyze the conversion of the pentose pathway...; cd04604
5934
hypothetical protein
5950
hypothetical protein,,
6256
hypothetical protein
6364
putative transcriptional regulator|Transcriptional regulator [Transcription]; COG1414|IclR helix-turn-helix domain; pfam09339|Bacterial transcriptional regulator. This family of bacterial transcriptional regulators includes the glycerol operon regulatory protein and acetate operon repressor both of which are members of the iclR family; pfam01614COG1414(3)PF09339(3)|PF01614(3)
6365
2-oxo-3-deoxygalactonate kinase|2-keto-3-deoxy-galactonokinase [Carbohydrate transport and metabolism]; COG3734COG3734(3)
6366
hypothetical protein,,
6376
sialic acid synthase NeuB|Sialic acid synthase [Cell envelope biogenesis, outer membrane]; COG2089|NeuB family. NeuB is the prokaryotic N-acetylneuraminic acid (Neu5Ac) synthase. It catalyses the direct formation of Neu5Ac (the most common sialic acid) by condensation of phosphoenolpyruvate (PEP) and N-acetylmannosamine (ManNAc); pfam03102|SAF domain. This domain family includes a range of different proteins. Such as antifreeze proteins and flagellar FlgA proteins, and CpaB pilus proteins; pfam08666COG2089(1)PF03102(1)|PF08666(1)
6377
acylneuraminate cytidylyltransferase|Cytidylyltransferase. This family consists of two main Cytidylyltransferase activities: 1) 3-deoxy-manno-octulosonate cytidylyltransferase,, EC:2.7.7; pfam02348|NnaC (CMP-NeuNAc synthetase) _like subfamily of SGNH_hydrolases, a diverse family of lipases and esterases; cd01841PF02348(1)
6378
polysialic acid biosynthesis protein P7|UDP-N-acetylglucosamine 2-epimerase. This family consists of UDP-N-acetylglucosamine 2-epimerases EC:5.1.3.14 this enzyme catalyses the production of UDP-ManNAc from UDP-GlcNAc; pfam02350PF02350(1)
6389
hypothetical protein
6409
hypothetical protein
6417
hypothetical protein
6419
hypothetical protein
6423
putative bacterial regulatory protein, MerR family|Predicted transcriptional regulator [Transcription]; COG2944COG2944(3)
6424
hypothetical proteinPF06296(1)
6443
putative cobalamin synthesis protein|The function of this protein family is unkown. The amino acid sequence of YjiA protein in E. coli contains several conserved motifs that characterizes it as a P-loop GTPase; cd03112|Cobalamin synthesis protein cobW C-terminal domain; pfam07683PF07683(3)
6678
hypothetical protein YjgX (putative sulfatase)|Sulfatase; pfam00884PF00884(3)
6767
C4-dicarboxylate-binding protein|TRAP-type C4-dicarboxylate transport system, periplasmic component [Carbohydrate transport and metabolism]; COG1638COG1638(3)
6768
C4-dicarboxylate transporter small subunit|TRAP-type C4-dicarboxylate transport system, small permease component [Carbohydrate transport and metabolism]; COG3090COG3090(3)
6769
C4-dicarboxylate transporter large subunit|DctM-like transporters. This family contains a diverse range of predicted transporter proteins. Including the DctM subunit of the bacterial and archaeal TRAP C4-dicarboxylate transport (Dct) system permease; pfam06808PF06808(3)
6771
putative conserved protein|KDPG and KHG aldolase. This family belongs to the class I adolases whose reaction mechanism involves Schiff base formation between a substrate carbonyl and lysine residue in the active site; cd00452
6772
hypothetical protein,,
6777
hypothetical protein (hypothetical flavodoxin)|Multimeric flavodoxin WrbA [General function prediction only]; COG0655COG0655(3)
6778
hypothetical beta-lactamase-related protein|Metallo-beta-lactamase superfamily; pfam00753PF00753(3)
6818
Hypothetical protein
6822
Hypothetical protein|LexA DNA binding domain. This is the DNA binding domain of the LexA SOS regulon repressor which prevents expression of DNA repair proteins. The aligned region contains a variant form of the helix-turn-helix DNA binding motif; pfam01726|Residues 12 to 119 of 119 are 95.37 pct identical to residues 1 to 108 of 108 from GenPept.129 : >gb|AAL89444.1| (U82619) unknown [Shigella flexneri bacteriophage V]PF01726(3)
7129
protein PapJ precursor
7130
PapK fimbrial adapter precursor|Fimbrial protein; pfam00419,PF00419(4)
7131
PapE protein|Fimbrial protein; pfam00419,PF00419(4)
7132
PapF protein|P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; COG3539COG3539(4)
7133
PapG|PapGII-like_RBD domain; PapG class II receptor binding domain; PapG adhesin located at the tip of the P pilus mediates the attachment of uropathogenic Escherichia coli to the uroepithelium of the human kidney; PapG has a C-terminal pilin region with a ch; cd00239PF03628(4)
7161
hypothetical protein
7355
transcriptional regulator MarR family (PapX protein)|DNA-binding transcriptional repressor of microcin B17 synthesis and multidrug efflux; PRK10870
7379
hypothetical protein|Plasmid maintenance system killer protein [General function prediction only]; COG3549COG3549(2)
7765
hypothetical protein|pyruvate formate lyase II activase; PRK10076|Acetyl-CoA synthase (ACS), also known as acetyl-CoA decarbonylase, is found in acetogenic and methanogenic organisms and is responsible for the synthesis and breakdown of acetyl-CoA; cd01916PF04055(1)
7766
hypothetical protein
7767
hypothetical protein
7772
hypothetical protein
7773
hypothetical protein
7802
hypothetical protein
7973
putative carnitine transporter CniT|Choline-glycine betaine transporter [Cell envelope biogenesis, outer membrane]; COG1292COG1292(1)
7974
putative DHA kinase PgdK|dihydroxyacetone kinase, C-terminal domain; PRK10005
7975
hypothetical protein,
7982
NeuE protein|Capsule polysaccharide biosynthesis protein. This family includes export proteins involved in capsule polysaccharide biosynthesis, such as KpsS and LipB; pfam05159PF05159(1)
7983
poly-alpha-2,8 sialosyl sialyltransferase|Alpha-2,8-polysialyltransferase (POLYST). This family contains the bacterial enzyme alpha-2,8-polysialyltransferase (EC:2.4.99.-) (approximately 500 residues long); pfam07388PF07388(1)
7984
hypothetical protein|Bacterial fructose-1,6-bisphosphatase, glpX-encoded. A dimeric enzyme dependent on Mg(2+). glpX-encoded FPBase (FBPase class II) differs from other members of the inositol-phosphatase superfamily by permutation of secondary structure elements; cd01516
7986
Hypothetical protein
8008
F1C minor fimbrial subunit protein G presursor|Fimbrial protein; pfam00419PF00419(3)
8022
hypothetical protein,
8023
hypothetical protein,
8028
hypothetical protein|Uncharacterized conserved protein [Function unknown]; COG4104|Peptidase family C39 mostly contains bacteriocin-processing endopeptidases from bacteria. The cysteine peptidases in family C39 cleave the 'double-glycine' leader peptides from the precursors of various bacteriocins (mostly non-lantibiotic); cd02259,COG4104(2)